Stock Trading History of Antinori Paul Michael

The following table details the trading activities (stock purchases, stock sales, and stock option exercises) reported to the Securities and Exchange Commission (SEC) by insider Antinori Paul Michael since year 2005. The trader's CIK number is 1318459. At the time of this reporting, Antinori Paul Michael is the SVP and General Counsel of Medicines Co /de (stock ticker symbol MDCO).

Stock purchases, sales, and option exercises reported by *Antinori Paul Michael* since 2005.
Trade Date	Symbol	Company Name (Issuer)	Trade Type	Shares	Price ($)	Value ($)
2007-08-03	MDCO	Medicines Co /de	Purchase	1,000	15.90	15,900
2006-10-26	MDCO	Medicines Co /de	Sale	5,000	25.00	125,000
2006-10-26	MDCO	Medicines Co /de	Option Exercise	5,000	9.13	45,650
2006-10-23	MDCO	Medicines Co /de	Sale	5,000	24.00	120,000
2006-10-23	MDCO	Medicines Co /de	Option Exercise	5,000	9.13	45,650
2006-08-21	MDCO	Medicines Co /de	Sale	5,000	22.00	110,000
2006-08-21	MDCO	Medicines Co /de	Option Exercise	5,000	9.13	45,650
2006-02-27	MDCO	Medicines Co /de	Sale	5,964	20.00	119,280
2006-02-27	MDCO	Medicines Co /de	Option Exercise	5,000	9.13	45,650

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Antinori Paul Michael (SVP and General Counsel of Medicines Co /de at the time of this reporting) see the Securities and Exchange Commission (SEC) website.