Insider Trading activities of Inspire Pharmaceuticals Inc insiders.

Monthly summaries of insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Inspire Pharmaceuticals Inc since 2005 are illustrated in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Inspire Pharmaceuticals Inc since year 2005. Table 2 shows the detailed insider transactions of Inspire Pharmaceuticals Inc since 2005. The reporting company's ticker symbol is ISPH. The reporting company's CIK number is 1040416.
The total value of stock buying since 2005 is $86,797,993.
The total value of stock sales since 2005 is $7,166,745.
The total value of stock option exercises since 2005 is $91,515.


Table 1. Monthly summaries of insider stock purchases, sales, and option exercises for Inspire Pharmaceuticals Inc (ISPH).
Trading Period Insider Buying Insider Sales Option Exercises
year-month Shares Value Shares Value Shares Value
2010-11 7,000 $48,895 7,934 $57,886 7,934 $21,897
2010-06 0 $0 0 $0 1,592 $0
2010-05 0 $0 2,000 $13,524 250,000 $0
2010-04 0 $0 2,000 $12,604 0 $0
2010-03 0 $0 2,000 $12,264 0 $0
2010-02 0 $0 2,000 $10,856 0 $0
2010-01 0 $0 2,000 $11,184 0 $0
2009-12 0 $0 7,000 $41,394 0 $0
2009-11 0 $0 2,000 $9,114 0 $0
2009-10 0 $0 2,000 $10,384 0 $0
2009-09 0 $0 2,000 $11,372 0 $0
2009-08 17,777,776 $79,999,992 12,000 $69,960 0 $0
2009-07 0 $0 2,000 $11,210 0 $0
2009-06 0 $0 6,125 $30,808 0 $0
2008-11 4,000 $14,558 0 $0 9,131 $3,835
2008-05 0 $0 0 $0 23,126 $7,284
2007-11 0 $0 5,000 $30,175 0 $0
2007-09 0 $0 5,000 $30,000 0 $0
2007-05 0 $0 5,000 $31,560 0 $0
2007-04 0 $0 403,330 $3,118,950 0 $0
2007-03 7,800 $49,522 0 $0 116,285 $58,499
2007-01 0 $0 500,000 $3,653,500 0 $0
2006-06 325,000 $1,308,125 0 $0 0 $0
2006-05 274,410 $1,330,830 0 $0 0 $0
2006-04 100,000 $484,999 0 $0 0 $0
2006-03 84,875 $419,265 0 $0 0 $0
2006-02 670,610 $3,141,807 0 $0 0 $0

Table 2. Detailed insider stock purchases, sales, and option exercises of Inspire Pharmaceuticals Inc insiders (ISPH)
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2010-11-15 Frey Kip (Director) Sale 7,934 7.30 57,886
2010-11-15 Frey Kip (Director) Option Ex 7,934 2.76 21,897
2010-11-09 Hutson Nancy J (Director) Buy 7,000 6.98 48,895
2010-06-03 Abercrombie George B (Director) Option Ex 1,592 .00 0
2010-05-19 Koven Andrew I (EVP & Chief Admin & Legal Ofc) Option Ex 250,000 .00 0
2010-05-03 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 6.76 13,524
2010-04-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 6.30 12,604
2010-03-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 6.13 12,264
2010-02-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 5.43 10,856
2010-01-04 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 5.59 11,184
2009-12-08 Shaffer Christy L (President & CEO) Sale 3,500 6.00 21,000
2009-12-07 Shaffer Christy L (President & CEO) Sale 1,500 6.00 9,000
2009-12-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 5.70 11,394
2009-11-02 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 4.56 9,114
2009-10-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 5.19 10,384
2009-09-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 5.69 11,372
2009-08-24 Shaffer Christy L (President & CEO) Sale 10,000 6.03 60,300
2009-08-10 Warburg Pincus Ix Llc (10% Owner) Buy 8,888,888 4.50 39,999,996
2009-08-10 Leff Jonathan S (Director) Buy 8,888,888 4.50 39,999,996
2009-08-03 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 4.83 9,660
2009-07-01 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 2,000 5.60 11,210
2009-06-15 Yerxa Benjamin R (EVP & Chf, Research & Develop) Sale 6,125 5.03 30,808
2008-11-10 Frey Kip (Director) Buy 2,000 3.40 6,800
2008-11-04 Lee Kenneth B Jr (Director) Buy 2,000 3.88 7,758
2008-11-04 Yerxa Benjamin R (EVP & Chf, Research & Develop) Option Ex 9,131 .42 3,835
2008-05-13 Yerxa Benjamin R (Chf Sci Off & EVP Strat Ops) Option Ex 23,126 .32 7,284
2007-11-13 Shaffer Christy L (President & CEO) Sale 5,000 6.04 30,175
2007-09-06 Shaffer Christy L (President & CEO) Sale 5,000 6.00 30,000
2007-05-16 Shaffer Christy L (President & CEO) Sale 5,000 6.31 31,560
2007-04-30 Deerfield Partners, Lp (10% Owner) Sale 403,330 7.73 3,118,950
2007-03-12 Hutson Nancy J (Director) Buy 7,800 6.35 49,522
2007-03-12 Staab Thomas R Ii (CFO & Treasurer) Option Ex 2,000 5.25 10,500
2007-03-12 Shaffer Christy L (President & CEO) Option Ex 114,285 .42 47,999
2007-01-16 Jay Jeffrey R (10% Owner) Sale 500,000 7.31 3,653,500
2006-06-28 Jay Jeffrey R (10% Owner) Buy 325,000 4.02 1,308,125
2006-05-10 Deerfield Special Situations Fund International Lt (Other) Buy 133,000 4.84 643,853
2006-05-09 Deerfield Special Situations Fund International Lt (Other) Buy 67,000 4.87 326,089
2006-05-02 Deerfield Special Situations Fund International Lt (Other) Buy 74,410 4.85 360,888
2006-04-11 Deerfield Special Situations Fund International Lt (Other) Buy 100,000 4.85 484,999
2006-03-28 Deerfield Special Situations Fund International Lt (Other) Buy 2,675 4.78 12,786
2006-03-07 Deerfield Special Situations Fund International Lt (Other) Buy 82,200 4.94 406,479
2006-02-22 Deerfield Special Situations Fund International Lt (Other) Buy 670,610 4.68 3,141,807

Insider trading activities including stock purchases, stock sales, and option exercises of ISPH listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Inspire Pharmaceuticals Inc (symbol ISPH, CIK number 1040416) see the Securities and Exchange Commission (SEC) website.