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Insider Trading: Isis Pharmaceuticals Inc

Monthly summaries of insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Isis Pharmaceuticals Inc in the last 24 months are illustrated in figures 1 and 2. Table 1 shows the monthly insider trading data of Isis Pharmaceuticals Inc since year 2005. Table 2 shows the detailed insider transactions of Isis Pharmaceuticals Inc since 2005. The reporting company's ticker symbol is ISIS. The reporting company's CIK number is 874015.

The total value of stock buying since 2005 is $90,940. The total value of stock sales is $11,517,133. The total value of stock exercises is $5,495,051.


1 year stock price chart,   1 day stock price chart
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Figure 1. Monthly insider transaction values at Isis Pharmaceuticals Inc (ISIS) in the past 24 months. The trade values of insider stock buys, sales, and option exercises are in logarithmic scale as shown on the right axis labels. The detailed monthly and daily insider transactions are listed in the 2 tables below.

  • 10

  • 11

  • 12

  • 01 2007

  • 02

  • 03

  • 04

  • 05

  • 06

  • 07

  • 08

  • 09

  • 10

  • 11

  • 12

  • 01 2008

  • 02

  • 03

  • 04

  • 05

  • 06

  • 07

  • 08

  • 09

  • $2,603k

    $260k

    $26k

    $2k

  • Buy
  • Sale
  • Option Exercise

Figure 2. Average prices of insider buys, sales, and option exercises at Isis Pharmaceuticals Inc (ISIS) in the past 24 months. See table 2 for insider transaction details.

  • 10

  • 11

  • 12

  • 01 2007

  • 02

  • 03

  • 04

  • 05

  • 06

  • 07

  • 08

  • 09

  • 10

  • 11

  • 12

  • 01 2008

  • 02

  • 03

  • 04

  • 05

  • 06

  • 07

  • 08

  • 09

  • $19.28

    $14.46

    $9.64

    $4.82



Table 1. Monthly summaries of insider stock purchases, sales, and option exercises for Isis Pharmaceuticals Inc (ISIS).
Trading Period
year-month  
Insider Buying     
Shares               Value ($)
Insider Sales     
Shares               Value ($)
Option Exercises     
Shares               Value ($)
2008-09 0 0 10,000 181,119 10,000 68,100
2008-08 0 0 84,000 1,545,771 74,000 559,022
2008-07 0 0 5,338 74,375 0 0
2008-06 0 0 0 0 4,000 53,000
2008-04 0 0 27,500 434,310 27,500 165,856
2008-01 0 0 2,406 46,387 0 0
2007-12 0 0 70,000 1,166,455 72,100 887,731
2007-11 0 0 79,851 1,438,703 79,851 444,482
2007-10 0 0 20,000 304,672 20,000 246,250
2007-09 0 0 105,466 1,521,791 105,466 888,286
2007-08 0 0 10,000 125,000 10,000 62,500
2007-07 0 0 32,669 370,420 29,799 164,414
2007-05 0 0 4,800 49,519 4,800 24,720
2007-04 0 0 19,711 199,278 16,000 77,450
2006-12 0 0 16,100 191,087 16,100 109,641
2006-11 0 0 220,688 2,603,188 160,688 933,617
2006-10 0 0 22,424 191,305 22,424 119,521
2006-08 4,000 24,520 0 0 0 0
2006-07 4,000 23,860 0 0 0 0
2006-05 0 0 8,500 72,660 8,500 49,300
2006-03 0 0 52,166 456,005 52,166 311,451
2006-02 2,000 10,960 62,059 496,620 60,559 329,710
2006-01 4,000 21,240 0 0 0 0
2005-12 2,000 10,360 0 0 0 0
2005-09 0 0 5,708 30,662 0 0
2005-06 0 0 4,446 17,806 0 0

Table 2. Detailed insider stock purchases, sales, and option exercises for Isis Pharmaceuticals Inc (ISIS)
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2008-09-02 Ecker David J (Vice President) Sale 10,000 18.11 181,119
2008-09-02 Ecker David J (Vice President) Option Exercise 10,000 6.81 68,100
2008-08-22 Ecker David J (Vice President) Sale 10,000 18.04 180,380
2008-08-22 Ecker David J (Vice President) Option Exercise 10,000 6.81 68,100
2008-08-20 Bennett C Frank (Senior Vice President) Sale 6,000 17.97 107,820
2008-08-20 Bennett C Frank (Senior Vice President) Option Exercise 6,000 6.81 40,860
2008-08-15 Bennett C Frank (Senior Vice President) Sale 1,000 19.25 19,250
2008-08-15 Bennett C Frank (Senior Vice President) Option Exercise 1,000 6.25 6,250
2008-08-14 Bennett C Frank (Senior Vice President) Sale 7,000 19.26 134,785
2008-08-14 Bennett C Frank (Senior Vice President) Option Exercise 7,000 6.25 43,750
2008-08-11 Treble Michael J (Vice President, Pres of Ibis) Sale 20,000 18.45 369,060
2008-08-11 Treble Michael J (Vice President, Pres of Ibis) Option Exercise 20,000 5.95 119,000
2008-08-11 Klein Joseph Iii (Director) Sale 10,000 18.60 185,964
2008-08-11 Ecker David J (Vice President) Sale 15,000 18.29 274,335
2008-08-11 Ecker David J (Vice President) Option Exercise 15,000 5.80 87,000
2008-08-11 Bennett C Frank (Senior Vice President) Sale 15,000 18.28 274,177
2008-08-11 Bennett C Frank (Senior Vice President) Option Exercise 15,000 12.94 194,062
2008-07-03 Parshall B Lynne (Director, COO) Sale 1,338 13.91 18,615
2008-07-03 Wender Joseph H (Director) Sale 4,000 13.94 55,760
2008-06-30 Wender Joseph H (Director) Option Exercise 4,000 13.25 53,000
2008-04-10 Ecker David J (Vice President) Sale 5,300 16.04 85,022
2008-04-10 Ecker David J (Vice President) Option Exercise 5,300 6.84 36,252
2008-04-07 Ecker David J (Vice President) Sale 12,200 16.06 195,988
2008-04-07 Ecker David J (Vice President) Option Exercise 12,200 6.32 77,104
2008-04-01 Bennett C Frank (Senior Vice President) Sale 10,000 15.33 153,300
2008-04-01 Bennett C Frank (Senior Vice President) Option Exercise 10,000 5.25 52,500
2008-01-08 Parshall B Lynne (Director, COO) Sale 2,406 19.28 46,387
2007-12-28 Crooke Stanley T (Chairman, President, CEO) Sale 20,000 16.22 324,430
2007-12-28 Crooke Stanley T (Chairman, President, CEO) Option Exercise 20,000 12.31 246,250
2007-12-27 Crooke Stanley T (Chairman, President, CEO) Sale 6,000 16.32 97,926
2007-12-27 Crooke Stanley T (Chairman, President, CEO) Option Exercise 8,100 12.31 99,731
2007-12-26 Crooke Stanley T (Chairman, President, CEO) Sale 24,000 16.53 396,619
2007-12-26 Crooke Stanley T (Chairman, President, CEO) Option Exercise 24,000 12.31 295,500
2007-12-11 Crooke Stanley T (Chairman, President, CEO) Sale 20,000 17.37 347,480
2007-12-11 Crooke Stanley T (Chairman, President, CEO) Option Exercise 20,000 12.31 246,250
2007-11-30 Crooke Stanley T (Chairman, President, CEO) Sale 29,851 18.03 538,153
2007-11-30 Crooke Stanley T (Chairman, President, CEO) Option Exercise 29,851 5.15 153,732
2007-11-28 Parshall B Lynne (Executive Vice President) Sale 20,000 18.01 360,220
2007-11-28 Parshall B Lynne (Executive Vice President) Option Exercise 20,000 6.81 136,250
2007-11-28 Crooke Stanley T (Chairman, President, CEO) Sale 30,000 18.01 540,330
2007-11-28 Crooke Stanley T (Chairman, President, CEO) Option Exercise 30,000 5.15 154,500
2007-10-01 Parshall B Lynne (Executive Vice President) Sale 20,000 15.23 304,672
2007-10-01 Parshall B Lynne (Executive Vice President) Option Exercise 20,000 12.31 246,250
2007-09-28 Parshall B Lynne (Executive Vice President) Sale 5,000 15.03 75,162
2007-09-28 Parshall B Lynne (Executive Vice President) Option Exercise 5,000 12.31 61,562
2007-09-27 Parshall B Lynne (Executive Vice President) Sale 20,000 15.27 305,496
2007-09-27 Parshall B Lynne (Executive Vice President) Option Exercise 20,000 12.31 246,250
2007-09-21 Treble Michael J (Vice President, Head of Ibis) Sale 10,000 14.95 149,500
2007-09-21 Treble Michael J (Vice President, Head of Ibis) Option Exercise 10,000 5.95 59,500
2007-09-20 Bennett C Frank (Vice President) Sale 14,000 14.76 206,570
2007-09-20 Bennett C Frank (Vice President) Option Exercise 14,000 12.31 172,375
2007-09-18 Ecker David J (Vice President) Sale 6,000 14.13 84,780
2007-09-18 Ecker David J (Vice President) Option Exercise 6,000 6.81 40,860
2007-09-14 Treble Michael J (Vice President, Head of Ibis) Sale 10,000 13.96 139,600
2007-09-14 Treble Michael J (Vice President, Head of Ibis) Option Exercise 10,000 5.95 59,500
2007-09-14 Ecker David J (Vice President) Sale 24,000 14.12 338,832
2007-09-14 Ecker David J (Vice President) Option Exercise 24,000 6.81 163,440
2007-09-14 Bennett C Frank (Vice President) Sale 10,000 13.76 137,600
2007-09-14 Bennett C Frank (Vice President) Option Exercise 10,000 5.15 51,500
2007-09-11 Parshall B Lynne (Executive Vice President) Sale 6,466 13.03 84,251
2007-09-11 Parshall B Lynne (Executive Vice President) Option Exercise 6,466 5.15 33,299
2007-08-21 Bennett C Frank (Vice President) Sale 10,000 12.50 125,000
2007-08-21 Bennett C Frank (Vice President) Option Exercise 10,000 6.25 62,500
2007-07-12 Treble Michael J (Vice President, Head of Ibis) Sale 10,000 11.95 119,500
2007-07-12 Treble Michael J (Vice President, Head of Ibis) Option Exercise 10,000 5.95 59,500
2007-07-10 Treble Michael J (Vice President, Head of Ibis) Sale 10,000 11.95 119,500
2007-07-10 Treble Michael J (Vice President, Head of Ibis) Option Exercise 10,000 5.25 52,500
2007-07-09 Bennett C Frank (Vice President) Sale 5,732 10.78 61,818
2007-07-09 Bennett C Frank (Vice President) Option Exercise 4,599 5.15 23,684
2007-07-06 Wedel Mark K (VP & Chief Medical Officer) Sale 5,200 10.12 52,626
2007-07-06 Wedel Mark K (VP & Chief Medical Officer) Option Exercise 5,200 5.52 28,730
2007-07-03 Parshall B Lynne (Executive Vice President) Sale 835 9.85 8,224
2007-07-02 Wedel Mark K (VP & Chief Medical Officer) Sale 902 9.70 8,752
2007-05-09 Wedel Mark K (VP & Chief Medical Officer) Sale 2,800 10.36 29,019
2007-05-09 Wedel Mark K (VP & Chief Medical Officer) Option Exercise 2,800 5.15 14,420
2007-05-02 Wedel Mark K (VP & Chief Medical Officer) Sale 2,000 10.25 20,500
2007-05-02 Wedel Mark K (VP & Chief Medical Officer) Option Exercise 2,000 5.15 10,300
2007-04-25 Wedel Mark K (VP & Chief Medical Officer) Sale 13,711 10.11 138,618
2007-04-25 Wedel Mark K (VP & Chief Medical Officer) Option Exercise 10,000 4.60 45,950
2007-04-25 Levin Arthur A (Vice President) Sale 6,000 10.11 60,660
2007-04-25 Levin Arthur A (Vice President) Option Exercise 6,000 5.25 31,500
2006-12-08 Ecker David J (Vice President) Sale 11,100 12.04 133,602
2006-12-08 Ecker David J (Vice President) Option Exercise 11,100 6.81 75,591
2006-12-04 Ecker David J (Vice President) Sale 5,000 11.50 57,485
2006-12-04 Ecker David J (Vice President) Option Exercise 5,000 6.81 34,050
2006-11-14 Ecker David J (Vice President) Sale 3,900 12.10 47,209
2006-11-14 Ecker David J (Vice President) Option Exercise 3,900 6.81 26,559
2006-11-13 Levin Arthur A (Vice President) Sale 30,000 13.36 400,800
2006-11-13 Levin Arthur A (Vice President) Option Exercise 30,000 6.81 204,300
2006-11-13 Ecker David J (Vice President) Sale 20,000 13.36 267,200
2006-11-13 Ecker David J (Vice President) Option Exercise 10,000 6.81 68,100
2006-11-13 Bennett C Frank (Vice President) Sale 10,000 13.36 133,600
2006-11-13 Bennett C Frank (Vice President) Option Exercise 10,000 5.15 51,500
2006-11-13 Parshall B Lynne (Executive Vice President) Sale 30,000 13.36 400,800
2006-11-13 Parshall B Lynne (Executive Vice President) Option Exercise 30,000 5.15 154,500
2006-11-13 Crooke Stanley T (Chairman, President, CEO) Sale 20,000 13.36 267,200
2006-11-10 Ecker David J (Vice President) Sale 6,788 10.40 70,629
2006-11-10 Ecker David J (Vice President) Option Exercise 6,788 5.15 34,958
2006-11-10 Crooke Stanley T (Chairman, President, CEO) Sale 10,000 10.40 104,050
2006-11-09 Levin Arthur A (Vice President) Sale 20,000 10.13 202,600
2006-11-09 Levin Arthur A (Vice President) Option Exercise 20,000 6.81 136,200
2006-11-09 Ecker David J (Vice President) Sale 20,000 10.13 202,600
2006-11-09 Ecker David J (Vice President) Option Exercise 20,000 5.15 103,000
2006-11-09 Bennett C Frank (Vice President) Sale 10,000 10.13 101,300
2006-11-09 Bennett C Frank (Vice President) Option Exercise 10,000 5.15 51,500
2006-11-09 Parshall B Lynne (Executive Vice President) Sale 20,000 10.13 202,600
2006-11-09 Parshall B Lynne (Executive Vice President) Option Exercise 20,000 5.15 103,000
2006-11-09 Crooke Stanley T (Chairman, President, CEO) Sale 20,000 10.13 202,600
2006-10-19 Levin Arthur A (Vice President) Sale 12,424 8.98 111,570
2006-10-19 Levin Arthur A (Vice President) Option Exercise 12,424 5.48 68,021
2006-10-06 Levin Arthur A (Vice President) Sale 10,000 7.97 79,735
2006-10-06 Levin Arthur A (Vice President) Option Exercise 10,000 5.15 51,500
2006-08-15 Klein Joseph Iii (Director) Purchase 2,000 6.26 12,520
2006-08-01 Klein Joseph Iii (Director) Purchase 2,000 6.00 12,000
2006-07-18 Klein Joseph Iii (Director) Purchase 2,000 5.91 11,820
2006-07-03 Klein Joseph Iii (Director) Purchase 2,000 6.02 12,040
2006-05-05 Bennett C Frank (Vice President) Sale 8,500 8.55 72,660
2006-05-05 Bennett C Frank (Vice President) Option Exercise 8,500 5.80 49,300
2006-03-21 Levin Arthur A (Vice President) Sale 500 9.04 4,517
2006-03-21 Levin Arthur A (Vice President) Option Exercise 500 6.84 3,420
2006-03-21 Ecker David J (Vice President) Sale 12,756 9.03 115,241
2006-03-21 Ecker David J (Vice President) Option Exercise 12,756 5.15 65,693
2006-03-20 Levin Arthur A (Vice President) Sale 9,500 9.04 85,918
2006-03-20 Levin Arthur A (Vice President) Option Exercise 9,500 6.84 64,980
2006-03-20 Ecker David J (Vice President) Sale 14,032 8.96 125,726
2006-03-20 Ecker David J (Vice President) Option Exercise 14,032 5.15 72,264
2006-03-08 Brown Richard K (Vice President) Sale 2,770 8.07 22,359
2006-03-08 Brown Richard K (Vice President) Option Exercise 2,770 6.84 18,946
2006-03-07 Brown Richard K (Vice President) Sale 2,000 7.97 15,940
2006-03-07 Brown Richard K (Vice President) Option Exercise 2,000 6.84 13,680
2006-03-03 Brown Richard K (Vice President) Sale 1,008 8.23 8,295
2006-03-03 Brown Richard K (Vice President) Option Exercise 1,008 6.84 6,894
2006-03-02 Brown Richard K (Vice President) Sale 3,600 8.19 29,495
2006-03-02 Brown Richard K (Vice President) Option Exercise 3,600 6.84 24,624
2006-03-01 Brown Richard K (Vice President) Sale 6,000 8.09 48,514
2006-03-01 Brown Richard K (Vice President) Option Exercise 6,000 6.82 40,950
2006-02-28 Brown Richard K (Vice President) Sale 2,000 8.01 16,020
2006-02-28 Brown Richard K (Vice President) Option Exercise 2,000 6.81 13,620
2006-02-27 Brown Richard K (Vice President) Sale 3,715 8.10 30,098
2006-02-27 Brown Richard K (Vice President) Option Exercise 3,715 6.81 25,299
2006-02-24 Brown Richard K (Vice President) Sale 1,000 8.02 8,020
2006-02-24 Brown Richard K (Vice President) Option Exercise 1,000 6.81 6,810
2006-02-22 Brown Richard K (Vice President) Sale 1,185 7.88 9,337
2006-02-22 Brown Richard K (Vice President) Option Exercise 1,185 5.80 6,873
2006-02-21 Brown Richard K (Vice President) Sale 3,100 8.06 24,986
2006-02-21 Brown Richard K (Vice President) Option Exercise 3,100 5.80 17,980
2006-02-17 Levin Arthur A (Vice President) Sale 7,770 8.03 62,393
2006-02-17 Levin Arthur A (Vice President) Option Exercise 7,770 5.15 40,015
2006-02-17 Brown Richard K (Vice President) Sale 12,000 8.11 97,268
2006-02-17 Brown Richard K (Vice President) Option Exercise 12,000 5.48 65,700
2006-02-17 Ecker David J (Vice President) Sale 26,789 8.02 214,898
2006-02-17 Ecker David J (Vice President) Option Exercise 26,789 5.15 137,963
2006-02-16 Levin Arthur A (Vice President) Sale 3,000 7.95 23,850
2006-02-16 Levin Arthur A (Vice President) Option Exercise 3,000 5.15 15,450
2006-02-09 Bennett C Frank (Vice President) Sale 1,500 6.50 9,750
2006-02-01 Klein Joseph Iii (Director) Purchase 2,000 5.48 10,960
2006-01-17 Klein Joseph Iii (Director) Purchase 2,000 5.46 10,920
2006-01-03 Klein Joseph Iii (Director) Purchase 2,000 5.16 10,320
2005-12-15 Klein Joseph Iii (Director) Purchase 2,000 5.18 10,360
2005-09-19 Parshall B Lynne (Executive Vice Presi) Sale 1,450 5.32 7,711
2005-09-15 Parshall B Lynne (Executive Vice Presi) Sale 1,558 5.28 8,223
2005-09-12 Parshall B Lynne (Executive Vice Presi) Sale 2,700 5.46 14,728
2005-06-24 Parshall B Lynne (Executive Vice Presi) Sale 4,446 4.00 17,806

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Isis Pharmaceuticals Inc (symbol ISIS, CIK number 874015) see the Securities and Exchange Commission (SEC) website.

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