Insider Trading History of Treu Jesse I

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) by Treu Jesse I since 2006. The trader's CIK number is 1013425. At the time of the last reporting, Treu Jesse I was the 10% Owner of Aldeyra Therapeutics, Inc.. (stock ticker symbol ALDX). Also see all insider trading activities at Aldeyra Therapeutics, Inc..

Note that in the past TREU JESSE I also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Esperion Therapeutics, Inc. (ESPR) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2013	ESPR	285,714	$3,999,996	0	$0	0	$0

Yearly summary of insider trading at Paratek Pharmaceuticals, Inc. (NOVC) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2009	NOVC	0	$0	250,000	$238,755	0	$0
2007	NOVC	0	$0	24,500	$275,870	0	$0
2006	NOVC	461,538	$2,999,997	0	$0	0	$0

Yearly summary of insider trading at Somaxon Pharmaceuticals, Inc. (SOMX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2009	SOMX	297,872	$312,765	1,397,266	$1,513,038	0	$0
2007	SOMX	0	$0	7,797	$111,551	0	$0
2006	SOMX	0	$0	12,918	$171,485	0	$0

Yearly summary of insider trading at Volcano Corp (VOLC) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2008	VOLC	0	$0	36,189	$498,961	0	$0
2007	VOLC	0	$0	54,433	$1,086,943	0	$0
2006	VOLC	0	$0	1,508,249	$25,263,170	0	$0

Yearly summary of insider trading at Durata Therapeutics, Inc. (DRTX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2012	DRTX	784,313	$7,058,817	0	$0	0	$0

Yearly summary of insider trading at Senorx Inc (SENO) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2008	SENO	0	$0	2,750	$23,182	0	$0

Yearly summary of insider trading at Alimera Sciences Inc (ALIM) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2011	ALIM	0	$0	6,914	$55,588	0	$0
2010	ALIM	378,028	$4,158,308	0	$0	0	$0

Yearly summary of insider trading at Clovis Oncology, Inc. (CLVS) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2011	CLVS	931,683	$12,111,879	0	$0	0	$0

Yearly summary of insider trading at Regado Biosciences Inc (RGDO) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2013	RGDO	750,000	$3,000,000	0	$0	0	$0

Yearly summary of insider trading at Cadence Pharmaceuticals Inc (CADX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2009	CADX	2,780,674	$19,826,205	0	$0	0	$0

Yearly summary of insider trading at Zogenix, Inc. (ZGNX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2011	ZGNX	3,500,000	$7,000,000	0	$0	0	$0
2010	ZGNX	2,349,999	$9,399,996	0	$0	0	$0

Yearly summary of insider trading at Reva Medical, Inc. (RVA) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2012	RVA	0	$0	1,695,717	$8,749,899	0	$0

Yearly summary of insider trading at Orexigen Therapeutics, Inc. (OREX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2011	OREX	469,147	$680,263	0	$0	0	$0
2009	OREX	2,162,910	$16,096,005	0	$0	0	$0
2008	OREX	490,301	$2,302,914	0	$0	0	$0
2007	OREX	525,000	$6,300,000	21,000	$299,670	0	$0

Yearly summary of insider trading at Aldeyra Therapeutics, Inc. (ALDX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	ALDX	0	$0	96,743	$968,397	0	$0

Yearly summary of insider trading at Vanda Pharmaceuticals Inc. (VNDA) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2006	VNDA	0	$0	12,900	$330,498	0	$0

Yearly summary of insider trading at Northstar Neuroscience, Inc. (NSTR) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2007	NSTR	0	$0	404,056	$5,309,631	0	$0
2006	NSTR	0	$0	12,530	$164,143	0	$0

Yearly summary of insider trading at Veracyte, Inc. (VCYT) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	VCYT	0	$0	1,052,151	$21,550,471	0	$0
2018	VCYT	0	$0	500,000	$5,413,600	0	$0
2017	VCYT	0	$0	2,226	$17,986	0	$0

Yearly summary of insider trading at Tranzyme Inc (OCRX) by Treu Jesse I

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2013	OCRX	1,327,491	$7,999,460	0	$0	0	$0

Insider trading activities at 18 companies by Treu Jesse I:

1. Esperion Therapeutics, Inc. (ESPR)

2. Paratek Pharmaceuticals, Inc. (NOVC)

3. Somaxon Pharmaceuticals, Inc. (SOMX)

4. Volcano Corp (VOLC)

5. Durata Therapeutics, Inc. (DRTX)

6. Senorx Inc (SENO)

7. Alimera Sciences Inc (ALIM)

8. Clovis Oncology, Inc. (CLVS)

9. Regado Biosciences Inc (RGDO)

10. Cadence Pharmaceuticals Inc (CADX)

11. Zogenix, Inc. (ZGNX)

12. Reva Medical, Inc. (RVA)

13. Orexigen Therapeutics, Inc. (OREX)

14. Aldeyra Therapeutics, Inc. (ALDX)

15. Vanda Pharmaceuticals Inc. (VNDA)

16. Northstar Neuroscience, Inc. (NSTR)

17. Veracyte, Inc. (VCYT)

18. Tranzyme Inc (OCRX)

Table 1. Insider trading of Esperion Therapeutics, Inc. (ESPR) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2013-07-01	ESPR	Buy	285,714	14.00	3,999,996

Table 2. Insider trading of Paratek Pharmaceuticals, Inc. (NOVC) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2009-01-30	NOVC	Sale	150,300	.98	147,294
2009-01-29	NOVC	Sale	63,000	.91	57,330
2009-01-28	NOVC	Sale	36,700	.93	34,131
2007-06-06	NOVC	Sale	24,500	11.26	275,870
2006-05-15	NOVC	Buy	461,538	6.50	2,999,997

Table 3. Insider trading of Somaxon Pharmaceuticals, Inc. (SOMX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2009-12-17	SOMX	Sale	816,292	1.04	848,943
2009-12-18	SOMX	Sale	80,474	1.10	88,521
2009-12-14	SOMX	Sale	35,000	1.15	40,250
2009-12-11	SOMX	Sale	408,000	1.15	469,199
2009-12-10	SOMX	Sale	57,500	1.15	66,125
2009-07-08	SOMX	Buy	297,872	1.05	312,765
2007-06-05	SOMX	Sale	3,500	14.07	49,245
2007-05-17	SOMX	Sale	4,297	14.50	62,306
2006-12-21	SOMX	Sale	6,459	13.52	87,325
2006-09-18	SOMX	Sale	6,459	13.03	84,160

Table 4. Insider trading of Volcano Corp (VOLC) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2008-07-16	VOLC	Sale	19,357	14.49	280,482
2008-04-08	VOLC	Sale	16,832	12.98	218,479
2007-06-01	VOLC	Sale	29,186	20.59	600,939
2007-05-18	VOLC	Sale	25,247	19.25	486,004
2006-12-06	VOLC	Sale	1,508,249	16.75	25,263,170

Table 5. Insider trading of Durata Therapeutics, Inc. (DRTX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2012-07-24	DRTX	Buy	784,313	9.00	7,058,817

Table 6. Insider trading of Senorx Inc (SENO) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2008-02-26	SENO	Sale	2,750	8.43	23,182

Table 7. Insider trading of Alimera Sciences Inc (ALIM) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2011-06-02	ALIM	Sale	6,914	8.04	55,588
2010-04-27	ALIM	Buy	378,028	11.00	4,158,308

Table 8. Insider trading of Clovis Oncology, Inc. (CLVS) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2011-11-21	CLVS	Buy	931,683	13.00	12,111,879

Table 9. Insider trading of Regado Biosciences Inc (RGDO) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2013-08-27	RGDO	Buy	750,000	4.00	3,000,000

Table 10. Insider trading of Cadence Pharmaceuticals Inc (CADX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2009-02-18	CADX	Buy	2,780,674	7.13	19,826,205

Table 11. Insider trading of Zogenix, Inc. (ZGNX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2011-09-16	ZGNX	Buy	3,500,000	2.00	7,000,000
2010-11-29	ZGNX	Buy	2,349,999	4.00	9,399,996

Table 12. Insider trading of Reva Medical, Inc. (RVA) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2012-03-23	RVA	Sale	1,695,717	5.16	8,749,899

Table 13. Insider trading of Orexigen Therapeutics, Inc. (OREX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2011-12-22	OREX	Buy	469,147	1.45	680,263
2009-12-17	OREX	Buy	100,000	7.55	755,000
2009-12-18	OREX	Buy	38,100	7.50	285,750
2009-11-24	OREX	Buy	50,000	6.75	337,500
2009-11-20	OREX	Buy	250,000	6.93	1,732,500
2009-11-23	OREX	Buy	150,000	6.93	1,039,500
2009-11-12	OREX	Buy	62,000	6.90	427,800
2009-11-10	OREX	Buy	84,400	6.93	584,892
2009-11-11	OREX	Buy	53,600	6.93	371,448
2009-08-18	OREX	Buy	13,784	7.73	106,550
2009-08-14	OREX	Buy	26,225	8.00	209,800
2009-08-17	OREX	Buy	63,201	7.64	482,855
2009-08-12	OREX	Buy	400,000	8.00	3,200,000
2009-08-13	OREX	Buy	13,000	7.85	102,050
2009-08-11	OREX	Buy	104,300	7.60	792,680
2009-08-11	OREX	Buy	104,300	7.60	792,680
2009-07-23	OREX	Buy	650,000	7.50	4,875,000
2008-12-08	OREX	Buy	248,411	4.47	1,110,397
2008-12-09	OREX	Buy	241,890	4.93	1,192,517
2007-11-27	OREX	Sale	21,000	14.27	299,670
2007-05-01	OREX	Buy	525,000	12.00	6,300,000

Table 14. Insider trading of Aldeyra Therapeutics, Inc. (ALDX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-03-26	ALDX	Sale	96,743	10.01	968,397

Table 15. Insider trading of Vanda Pharmaceuticals Inc. (VNDA) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2006-12-12	VNDA	Sale	12,900	25.62	330,498

Table 16. Insider trading of Northstar Neuroscience, Inc. (NSTR) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2007-05-15	NSTR	Sale	379,000	13.20	5,002,800
2007-05-04	NSTR	Sale	15,971	13.00	207,623
2007-03-05	NSTR	Sale	9,085	10.92	99,208
2006-11-06	NSTR	Sale	12,530	13.10	164,143

Table 17. Insider trading of Veracyte, Inc. (VCYT) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-02-28	VCYT	Sale	350,000	20.84	7,294,000
2019-03-01	VCYT	Sale	275,000	20.45	5,623,750
2019-03-04	VCYT	Sale	427,151	20.21	8,632,721
2018-08-01	VCYT	Sale	120,000	10.85	1,302,000
2018-07-31	VCYT	Sale	380,000	10.82	4,111,600
2017-05-16	VCYT	Sale	2,226	8.08	17,986

Table 18. Insider trading of Tranzyme Inc (OCRX) by Treu Jesse I

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2013-07-15	OCRX	Buy	1,327,491	6.03	7,999,460

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Treu Jesse I (10% Owner of Aldeyra Therapeutics, Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

▪ Real-time Insider Trading

▪ Insider Officer Cluster Trading

▪ Top Officer Buys of the Week

▪ Top Officer Buys of the Month