Insider Trading History of Sanofi

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Sanofi since 2013. This trader's CIK number is 1121404. At the time of last reporting, Sanofi was the 10% Owner of Translate Bio, Inc.. (stock ticker symbol TBIO). Also see all insider trading activities at Translate Bio, Inc..

Note that in the past Sanofi also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Icosavax, Inc. (ICVX) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	ICVX	66,667	$1,000,005	0	$0	0	$0

Yearly summary of insider trading at Fulcrum Therapeutics, Inc. (FULC) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	FULC	93,750	$1,500,000	0	$0	0	$0

Yearly summary of insider trading at Inozyme Pharma, Inc. (INZY) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	INZY	81,250	$1,300,000	0	$0	0	$0

Yearly summary of insider trading at Humanigen, Inc (KBIO) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2013	KBIO	87,500	$700,000	0	$0	0	$0

Yearly summary of insider trading at Myokardia, Inc. (MYOK) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	MYOK	0	$0	4,168,899	$157,000,736	0	$0
2018	MYOK	150,000	$7,350,000	0	$0	0	$0
2017	MYOK	350,000	$12,425,000	0	$0	0	$0
2016	MYOK	450,000	$6,750,000	0	$0	0	$0
2015	MYOK	900,000	$9,000,000	0	$0	0	$0

Yearly summary of insider trading at Regeneron Pharmaceuticals, Inc. (REGN) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	REGN	0	$0	23,070,599	$11,770,477,328	0	$0
2019	REGN	0	$0	304,019	$102,653,062	0	$0
2018	REGN	0	$0	226,153	$80,131,125	0	$0
2017	REGN	462,141	$212,021,764	0	$0	0	$0
2016	REGN	148,669	$62,482,433	0	$0	0	$0
2015	REGN	249,426	$126,235,455	0	$0	0	$0
2014	REGN	6,428,301	$2,018,253,320	0	$0	0	$0

Yearly summary of insider trading at Regulus Therapeutics Inc. (RGLS) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2014	RGLS	1,303,780	$9,999,992	0	$0	0	$0

Yearly summary of insider trading at Alnylam Pharmaceuticals, Inc. (ALNY) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2017	ALNY	297,501	$21,381,396	0	$0	0	$0
2016	ALNY	205,030	$14,300,842	0	$0	0	$0
2015	ALNY	940,817	$1,899,204,337	0	$0	0	$0
2014	ALNY	344,448	$23,036,682	0	$0	0	$0

Yearly summary of insider trading at Voyager Therapeutics, Inc. (VYGR) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	VYGR	125,000	$1,750,000	0	$0	0	$0

Yearly summary of insider trading at Translate Bio, Inc. (TBIO) by Sanofi

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	TBIO	71,983,597	$2,735,376,686	0	$0	0	$0

Insider trading activities at 10 companies by Sanofi:

1. Icosavax, Inc. (ICVX)

2. Fulcrum Therapeutics, Inc. (FULC)

3. Inozyme Pharma, Inc. (INZY)

4. Humanigen, Inc (KBIO)

5. Myokardia, Inc. (MYOK)

6. Regeneron Pharmaceuticals, Inc. (REGN)

7. Regulus Therapeutics Inc. (RGLS)

8. Alnylam Pharmaceuticals, Inc. (ALNY)

9. Voyager Therapeutics, Inc. (VYGR)

10. Translate Bio, Inc. (TBIO)

Table 1. Insider trading of Icosavax, Inc. (ICVX) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-08-02	ICVX	Buy	66,667	15.00	1,000,005

Table 2. Insider trading of Fulcrum Therapeutics, Inc. (FULC) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-07-22	FULC	Buy	93,750	16.00	1,500,000

Table 3. Insider trading of Inozyme Pharma, Inc. (INZY) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-28	INZY	Buy	81,250	16.00	1,300,000

Table 4. Insider trading of Humanigen, Inc (KBIO) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2013-01-31	KBIO	Buy	87,500	8.00	700,000

Table 5. Insider trading of Myokardia, Inc. (MYOK) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-02-13	MYOK	Sale	4,168,899	37.66	157,000,736
2018-05-25	MYOK	Buy	150,000	49.00	7,350,000
2017-08-14	MYOK	Buy	350,000	35.50	12,425,000
2016-10-03	MYOK	Buy	450,000	15.00	6,750,000
2015-11-03	MYOK	Buy	900,000	10.00	9,000,000

Table 6. Insider trading of Regeneron Pharmaceuticals, Inc. (REGN) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-06-09	REGN	Sale	120,234	597.48	71,837,410
2020-05-29	REGN	Sale	22,821,451	509.85	11,635,516,792
2020-03-09	REGN	Sale	128,914	489.65	63,123,126
2019-09-10	REGN	Sale	172,904	281.15	48,611,786
2019-03-08	REGN	Sale	131,115	412.17	54,041,276
2018-09-06	REGN	Sale	104,552	406.68	42,519,207
2018-06-08	REGN	Sale	121,601	309.31	37,611,918
2017-08-25	REGN	Buy	72,378	482.99	34,957,488
2017-08-23	REGN	Buy	60,595	478.30	28,982,467
2017-08-24	REGN	Buy	105,820	481.79	50,983,335
2017-06-02	REGN	Buy	136,050	475.63	64,709,869
2017-01-11	REGN	Buy	87,298	371.01	32,388,605
2016-06-14	REGN	Buy	64,731	364.22	23,576,583
2016-01-12	REGN	Buy	83,938	463.51	38,905,850
2015-10-06	REGN	Buy	11,040	473.60	5,228,532
2015-10-06	REGN	Buy	80,538	459.17	36,980,633
2015-09-23	REGN	Buy	147,209	532.00	78,315,924
2015-07-27	REGN	Buy	10,639	536.74	5,710,366
2014-12-23	REGN	Buy	171,457	391.47	67,119,585
2014-12-24	REGN	Buy	30,002	396.41	11,893,032
2014-10-16	REGN	Buy	122,127	334.12	40,804,828
2014-10-15	REGN	Buy	158,368	329.35	52,157,867
2014-09-16	REGN	Buy	31,717	348.94	11,067,171
2014-09-15	REGN	Buy	80,824	343.90	27,795,454
2014-09-12	REGN	Buy	59,808	346.50	20,723,172
2014-07-15	REGN	Buy	129,100	315.06	40,674,246
2014-07-11	REGN	Buy	150,000	315.10	47,264,850
2014-07-14	REGN	Buy	150,000	317.06	47,558,250
2014-07-10	REGN	Buy	175,000	310.54	54,343,800
2014-07-08	REGN	Buy	153,000	312.20	47,766,447
2014-07-09	REGN	Buy	195,000	307.80	60,021,000
2014-07-07	REGN	Buy	256,700	313.46	80,464,411
2014-07-03	REGN	Buy	100,000	311.20	31,120,000
2014-07-01	REGN	Buy	212,400	295.93	62,855,319
2014-07-02	REGN	Buy	212,400	305.58	64,905,616
2014-06-27	REGN	Buy	50,000	275.22	13,760,950
2014-06-30	REGN	Buy	212,400	280.15	59,504,921
2014-05-19	REGN	Buy	190,751	299.45	57,119,623
2014-03-28	REGN	Buy	306,945	307.76	94,466,314
2014-03-27	REGN	Buy	306,945	310.48	95,301,511
2014-03-21	REGN	Buy	305,115	322.74	98,471,899
2014-03-24	REGN	Buy	306,945	306.70	94,140,031
2014-03-20	REGN	Buy	57,957	327.72	18,993,841
2014-03-19	REGN	Buy	9,746	327.57	3,192,497
2014-03-14	REGN	Buy	55,583	327.98	18,230,223
2014-03-17	REGN	Buy	60,128	328.59	19,757,639
2014-03-12	REGN	Buy	220,995	332.33	73,444,373
2014-03-10	REGN	Buy	199,822	328.89	65,718,658
2014-03-11	REGN	Buy	180,710	332.15	60,023,368
2014-03-06	REGN	Buy	80,404	339.23	27,275,609
2014-03-07	REGN	Buy	69,873	316.13	22,088,741
2014-03-07	REGN	Buy	241,818	333.50	80,646,061
2014-03-03	REGN	Buy	251,594	334.42	84,137,310
2014-02-07	REGN	Buy	21,986	287.22	6,314,906
2014-02-06	REGN	Buy	146,525	285.61	41,849,005
2014-02-04	REGN	Buy	190,286	285.07	54,245,591
2014-02-05	REGN	Buy	206,978	281.27	58,217,322
2014-01-31	REGN	Buy	10,914	288.13	3,144,661
2014-02-03	REGN	Buy	198,058	284.15	56,278,180
2014-01-27	REGN	Buy	74,685	272.68	20,365,329
2014-01-28	REGN	Buy	83,235	276.68	23,029,709

Table 7. Insider trading of Regulus Therapeutics Inc. (RGLS) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2014-02-04	RGLS	Buy	1,303,780	7.67	9,999,992

Table 8. Insider trading of Alnylam Pharmaceuticals, Inc. (ALNY) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2017-05-31	ALNY	Buy	297,501	71.87	21,381,396
2016-02-01	ALNY	Buy	205,030	69.75	14,300,842
2015-01-29	ALNY	Buy	97,118	95.00	9,226,210
2015-01-22	ALNY	Buy	196,251	9,317.00	1,828,470,567
2015-01-26	ALNY	Buy	647,448	95.00	61,507,560
2014-03-25	ALNY	Buy	344,448	66.88	23,036,682

Table 9. Insider trading of Voyager Therapeutics, Inc. (VYGR) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-11-16	VYGR	Buy	125,000	14.00	1,750,000

Table 10. Insider trading of Translate Bio, Inc. (TBIO) by Sanofi

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-09-14	TBIO	Buy	71,983,597	38.00	2,735,376,686

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Sanofi (10% Owner of Translate Bio, Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

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