1. Corporate Officers - P
2. Papadopoulos Stelios

Insider Trading History of Papadopoulos Stelios

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Papadopoulos Stelios since 2007. This trader's CIK number is 1202098. At the time of last reporting, Papadopoulos Stelios was the Director of Exelixis, Inc.. (stock ticker symbol EXEL). Also see all insider trading activities at Exelixis, Inc..

Note that in the past PAPADOPOULOS STELIOS also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Exelixis, Inc. (EXEL) by Papadopoulos Stelios

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2025	EXEL	0	$0	36,508	$1,619,129	36,508	$735,088
2024	EXEL	0	$0	11,437	$240,177	11,686	$228,695
2022	EXEL	0	$0	84,515	$1,653,113	0	$0
2021	EXEL	0	$0	20,770	$518,979	120,000	$512,399
2020	EXEL	0	$0	45,000	$1,162,800	165,791	$939,253
2019	EXEL	0	$0	26,250	$557,812	26,250	$114,581
2018	EXEL	0	$0	30,000	$693,000	30,000	$294,450
2017	EXEL	0	$0	220,000	$6,005,986	10,000	$105,300
2010	EXEL	200,000	$611,600	0	$0	0	$0
2008	EXEL	300,000	$968,700	0	$0	0	$0

Yearly summary of insider trading at Anadys Pharmaceuticals Inc (ANDS) by Papadopoulos Stelios

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2007	ANDS	164,304	$369,447	0	$0	0	$0

Yearly summary of insider trading at Bg Medicine, Inc. (BGMD) by Papadopoulos Stelios

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2013	BGMD	250,000	$500,000	0	$0	0	$0
2011	BGMD	75,000	$525,000	1,078	$4,322	336,441	$302,796

Yearly summary of insider trading at Biogen Inc. (BIIB) by Papadopoulos Stelios

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	BIIB	10,000	$3,048,780	0	$0	0	$0
2013	BIIB	0	$0	48,695	$8,494,089	46,675	$2,672,470

Yearly summary of insider trading at Regulus Therapeutics Inc. (RGLS) by Papadopoulos Stelios

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	RGLS	420,370	$454,549	0	$0	0	$0
2018	RGLS	616,401	$793,817	0	$0	0	$0
2017	RGLS	1,500,000	$1,517,900	0	$0	0	$0
2015	RGLS	0	$0	0	$0	50,677	$80,728
2014	RGLS	0	$0	0	$0	150,000	$57,000

Insider trading activities at 5 companies by Papadopoulos Stelios:

1. Exelixis, Inc. (EXEL)

2. Anadys Pharmaceuticals Inc (ANDS)

3. Bg Medicine, Inc. (BGMD)

4. Biogen Inc. (BIIB)

5. Regulus Therapeutics Inc. (RGLS)

Table 1. Insider trading of Exelixis, Inc. (EXEL) by Papadopoulos Stelios

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2025-05-15	EXEL	Sale	36,508	44.35	1,619,129
2025-05-15	EXEL	Option Ex	36,508	20.14	735,088
2024-05-20	EXEL	Option Ex	11,686	19.57	228,695
2024-05-20	EXEL	Sale	11,437	21.00	240,177
2022-02-22	EXEL	Sale	84,515	19.56	1,653,113
2021-05-11	EXEL	Sale	20,770	24.99	518,979
2021-05-11	EXEL	Option Ex	120,000	4.27	512,399
2020-05-13	EXEL	Option Ex	120,791	5.82	703,003
2020-05-08	EXEL	Option Ex	45,000	5.25	236,250
2020-05-08	EXEL	Sale	45,000	25.84	1,162,800
2019-02-21	EXEL	Sale	26,250	21.25	557,812
2019-02-21	EXEL	Option Ex	26,250	4.37	114,581
2018-05-07	EXEL	Option Ex	15,000	11.66	174,900
2018-05-07	EXEL	Sale	15,000	22.15	332,250
2018-03-02	EXEL	Option Ex	15,000	7.97	119,550
2018-03-02	EXEL	Sale	15,000	24.05	360,750
2017-09-22	EXEL	Sale	10,000	25.40	254,000
2017-09-18	EXEL	Sale	72,210	27.76	2,004,549
2017-09-19	EXEL	Sale	127,790	27.63	3,530,837
2017-03-20	EXEL	Sale	10,000	21.66	216,600
2017-03-20	EXEL	Option Ex	10,000	10.53	105,300
2010-08-24	EXEL	Buy	200,000	3.06	611,600
2008-10-30	EXEL	Buy	300,000	3.23	968,700

Table 2. Insider trading of Anadys Pharmaceuticals Inc (ANDS) by Papadopoulos Stelios

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2007-09-14	ANDS	Buy	2,869	2.30	6,598
2007-09-06	ANDS	Buy	200	2.30	459
2007-08-31	ANDS	Buy	32,913	2.22	73,099
2007-09-05	ANDS	Buy	89,333	2.30	205,465
2007-08-17	ANDS	Buy	38,989	2.15	83,826

Table 3. Insider trading of Bg Medicine, Inc. (BGMD) by Papadopoulos Stelios

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2013-01-30	BGMD	Buy	250,000	2.00	500,000
2011-11-29	BGMD	Sale	1,078	4.01	4,322
2011-11-09	BGMD	Option Ex	336,441	.90	302,796
2011-02-09	BGMD	Buy	75,000	7.00	525,000

Table 4. Insider trading of Biogen Inc. (BIIB) by Papadopoulos Stelios

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-07-27	BIIB	Buy	10,000	304.88	3,048,780
2013-06-11	BIIB	Sale	2,020	219.62	443,632
2013-03-11	BIIB	Sale	46,675	172.48	8,050,457
2013-03-11	BIIB	Option Ex	46,675	57.26	2,672,470

Table 5. Insider trading of Regulus Therapeutics Inc. (RGLS) by Papadopoulos Stelios

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-05-07	RGLS	Buy	370,370	1.08	399,999
2018-12-28	RGLS	Buy	50,000	1.09	54,550
2018-12-26	RGLS	Buy	90,000	.95	85,860
2018-12-27	RGLS	Buy	26,401	1.04	27,457
2018-11-16	RGLS	Buy	300,000	1.39	415,500
2018-11-15	RGLS	Buy	200,000	1.32	265,000
2017-07-25	RGLS	Buy	1,000,000	.91	910,000
2017-03-21	RGLS	Buy	200,000	1.20	239,800
2017-03-22	RGLS	Buy	300,000	1.23	368,100
2015-08-07	RGLS	Option Ex	50,677	1.59	80,728
2014-12-12	RGLS	Option Ex	150,000	.38	57,000

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Papadopoulos Stelios (Director of Exelixis, Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

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