Insider Trading History of Mott David M

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Mott David M since 2015. This trader's CIK number is 1219871. At the time of last reporting, Mott David M was the Officer of Ardelyx, Inc.. (stock ticker symbol ARDX). Also see all insider trading activities at Ardelyx, Inc..

Note that in the past MOTT DAVID M also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Ra Pharmaceuticals, Inc. (RARX) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	RARX	338,462	$4,400,006	435	$5,655	0	$0

Yearly summary of insider trading at Aveo Pharmaceuticals, Inc. (AVEO) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	AVEO	4,347,827	$4,956,522	0	$0	0	$0
2018	AVEO	4,533,344	$9,165,584	0	$0	0	$0
2017	AVEO	6,000,000	$3,000,000	0	$0	0	$0

Yearly summary of insider trading at Rhythm Pharmaceuticals, Inc. (RYTM) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2017	RYTM	550,000	$9,350,000	0	$0	0	$0

Yearly summary of insider trading at Adaptimmune Therapeutics Plc (ADAP) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	ADAP	7,500,000	$5,002,500	0	$0	0	$0
2018	ADAP	22,839,672	$40,012,335	0	$0	0	$0
2017	ADAP	12,870,000	$9,009,000	0	$0	0	$0

Yearly summary of insider trading at Achaogen, Inc. (AKAO) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	AKAO	500,000	$6,750,000	0	$0	0	$0

Yearly summary of insider trading at Novavax Inc (NVAX) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2025	NVAX	0	$0	0	$0	10,420	$0
2024	NVAX	0	$0	0	$0	6,670	$0
2023	NVAX	0	$0	0	$0	3,100	$0
2022	NVAX	0	$0	0	$0	700	$0
2021	NVAX	0	$0	24,961	$6,326,065	0	$0

Yearly summary of insider trading at Genocea Biosciences, Inc. (GNCA) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	GNCA	12,805,411	$14,685,631	0	$0	0	$0

Yearly summary of insider trading at Enliven Therapeutics, Inc. (IMRA) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	IMRA	229,224	$313,583	0	$0	0	$0

Yearly summary of insider trading at Tracon Pharmaceuticals, Inc. (TCON) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	TCON	869,565	$4,999,998	0	$0	0	$0
2015	TCON	500,000	$5,000,000	0	$0	0	$0

Yearly summary of insider trading at Regulus Therapeutics Inc. (RGLS) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	RGLS	1,136,704	$1,227,640	0	$0	0	$0

Yearly summary of insider trading at Appian Corp (APPN) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2017	APPN	0	$0	3,390,136	$66,073,749	0	$0

Yearly summary of insider trading at Synlogic, Inc. (MIRN) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	MIRN	857,142	$5,999,994	0	$0	0	$0

Yearly summary of insider trading at Tesaro, Inc. (TSRO) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	TSRO	145,532	$8,386,945	0	$0	0	$0
2016	TSRO	1,420,858	$49,999,993	0	$0	0	$0

Yearly summary of insider trading at Oruka Therapeutics, Inc. (ABIO) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	ABIO	0	$0	1,460,209	$731,564	0	$0

Yearly summary of insider trading at Surface Oncology, Inc. (SURF) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	SURF	133,333	$1,999,995	0	$0	0	$0

Yearly summary of insider trading at Epizyme, Inc. (EPZM) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	EPZM	62,717	$497,205	0	$0	0	$0
2020	EPZM	62,019	$994,164	0	$0	0	$0
2019	EPZM	0	$0	157,417	$2,024,958	0	$0
2018	EPZM	416,667	$3,750,003	0	$0	0	$0
2017	EPZM	200,000	$3,050,000	0	$0	0	$0
2016	EPZM	1,111,111	$9,999,999	0	$0	0	$0

Yearly summary of insider trading at Ardelyx, Inc. (ARDX) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2025	ARDX	1,158,106	$4,784,370	0	$0	0	$0
2024	ARDX	215,868	$996,662	0	$0	0	$0
2022	ARDX	1,701,000	$3,002,265	0	$0	0	$0
2020	ARDX	315,644	$1,998,216	0	$0	0	$0
2016	ARDX	2,527,301	$23,333,337	0	$0	0	$0
2015	ARDX	2,803,738	$29,999,996	0	$0	0	$0

Yearly summary of insider trading at Trevi Therapeutics, Inc. (TRVI) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	TRVI	2,500,000	$25,000,000	0	$0	0	$0

Yearly summary of insider trading at Interleukin Genetics Inc (ILIU) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	ILIU	20,120,724	$1,991,951	0	$0	0	$0

Yearly summary of insider trading at Mirum Pharmaceuticals, Inc. (MIRM) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	MIRM	450,000	$6,750,000	0	$0	0	$0

Yearly summary of insider trading at Mersana Therapeutics, Inc. (MRSN) by Mott David M

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	MRSN	538,599	$3,010,768	0	$0	0	$0
2019	MRSN	3,750,000	$15,000,000	0	$0	0	$0
2017	MRSN	1,000,000	$15,000,000	0	$0	0	$0

Insider trading activities at 21 companies by Mott David M:

1. Ra Pharmaceuticals, Inc. (RARX)

2. Aveo Pharmaceuticals, Inc. (AVEO)

3. Rhythm Pharmaceuticals, Inc. (RYTM)

4. Adaptimmune Therapeutics Plc (ADAP)

5. Achaogen, Inc. (AKAO)

6. Novavax Inc (NVAX)

7. Genocea Biosciences, Inc. (GNCA)

8. Enliven Therapeutics, Inc. (IMRA)

9. Tracon Pharmaceuticals, Inc. (TCON)

10. Regulus Therapeutics Inc. (RGLS)

11. Appian Corp (APPN)

12. Synlogic, Inc. (MIRN)

13. Tesaro, Inc. (TSRO)

14. Oruka Therapeutics, Inc. (ABIO)

15. Surface Oncology, Inc. (SURF)

16. Epizyme, Inc. (EPZM)

17. Ardelyx, Inc. (ARDX)

18. Trevi Therapeutics, Inc. (TRVI)

19. Interleukin Genetics Inc (ILIU)

20. Mirum Pharmaceuticals, Inc. (MIRM)

21. Mersana Therapeutics, Inc. (MRSN)

Table 1. Insider trading of Ra Pharmaceuticals, Inc. (RARX) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-10-31	RARX	Sale	435	13.00	5,655
2016-10-31	RARX	Buy	338,462	13.00	4,400,006

Table 2. Insider trading of Aveo Pharmaceuticals, Inc. (AVEO) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-04-08	AVEO	Buy	4,347,827	1.14	4,956,522
2018-12-20	AVEO	Buy	200,000	1.63	326,000
2018-12-21	AVEO	Buy	300,000	1.50	448,500
2018-12-11	AVEO	Buy	61,200	1.98	121,114
2018-12-07	AVEO	Buy	117,100	1.98	232,326
2018-12-10	AVEO	Buy	26,000	1.98	51,584
2018-12-06	AVEO	Buy	27,300	1.99	54,408
2018-11-28	AVEO	Buy	24,500	1.99	48,828
2018-11-30	AVEO	Buy	71,900	1.98	142,074
2018-11-20	AVEO	Buy	170,000	1.98	336,090
2018-11-15	AVEO	Buy	340,000	1.86	632,060
2018-11-16	AVEO	Buy	350,000	1.85	649,250
2018-11-19	AVEO	Buy	510,000	1.88	956,760
2018-08-21	AVEO	Buy	663,716	2.26	1,499,998
2018-07-18	AVEO	Buy	200,000	1.95	390,600
2018-07-19	AVEO	Buy	50,600	2.00	101,149
2018-06-27	AVEO	Buy	5,295	2.15	11,384
2018-06-28	AVEO	Buy	187,130	2.10	392,785
2018-05-30	AVEO	Buy	275	2.15	591
2018-05-21	AVEO	Buy	32,200	2.15	69,069
2018-05-18	AVEO	Buy	20,100	2.14	42,933
2018-05-17	AVEO	Buy	184,179	2.12	391,380
2018-05-08	AVEO	Buy	70,873	2.13	151,242
2018-04-06	AVEO	Buy	685,676	2.24	1,537,285
2018-04-09	AVEO	Buy	32,100	2.43	78,099
2018-04-10	AVEO	Buy	203,200	2.46	500,075
2017-03-28	AVEO	Buy	6,000,000	.50	3,000,000

Table 3. Insider trading of Rhythm Pharmaceuticals, Inc. (RYTM) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2017-10-10	RYTM	Buy	550,000	17.00	9,350,000

Table 4. Insider trading of Adaptimmune Therapeutics Plc (ADAP) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-01-24	ADAP	Buy	7,500,000	.67	5,002,500
2018-09-07	ADAP	Buy	15,000,000	1.67	25,005,000
2018-03-27	ADAP	Buy	6,000,000	1.92	11,502,000
2018-03-26	ADAP	Buy	571,164	1.90	1,087,496
2018-03-22	ADAP	Buy	869,574	1.90	1,655,668
2018-03-23	ADAP	Buy	294,090	1.95	572,299
2018-03-21	ADAP	Buy	104,844	1.81	189,872
2017-03-27	ADAP	Buy	12,870,000	.70	9,009,000

Table 5. Insider trading of Achaogen, Inc. (AKAO) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-12-19	AKAO	Buy	500,000	13.50	6,750,000

Table 6. Insider trading of Novavax Inc (NVAX) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2025-06-12	NVAX	Option Ex	10,420	.00	0
2024-06-12	NVAX	Option Ex	6,670	.00	0
2023-06-10	NVAX	Option Ex	3,100	.00	0
2022-06-17	NVAX	Option Ex	700	.00	0
2021-09-23	NVAX	Sale	24,961	253.44	6,326,065

Table 7. Insider trading of Genocea Biosciences, Inc. (GNCA) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-06-24	GNCA	Buy	2,857,142	3.50	9,999,997
2019-02-14	GNCA	Buy	9,948,269	.47	4,685,634

Table 8. Insider trading of Enliven Therapeutics, Inc. (IMRA) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-02-18	IMRA	Buy	50,398	1.30	65,517
2022-02-22	IMRA	Buy	65,817	1.56	102,674
2022-02-23	IMRA	Buy	35,257	1.46	51,475
2022-02-15	IMRA	Buy	19,552	1.20	23,462
2022-02-16	IMRA	Buy	11,779	1.20	14,134
2022-02-17	IMRA	Buy	14,595	1.17	17,076
2022-02-10	IMRA	Buy	8,753	1.29	11,291
2022-02-11	IMRA	Buy	14,573	1.23	17,924
2022-02-14	IMRA	Buy	8,500	1.18	10,030

Table 9. Insider trading of Tracon Pharmaceuticals, Inc. (TCON) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-11-29	TCON	Buy	869,565	5.75	4,999,998
2015-02-04	TCON	Buy	500,000	10.00	5,000,000

Table 10. Insider trading of Regulus Therapeutics Inc. (RGLS) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-05-07	RGLS	Buy	1,136,704	1.08	1,227,640

Table 11. Insider trading of Appian Corp (APPN) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2017-11-27	APPN	Sale	569,620	19.49	11,101,893
2017-11-20	APPN	Sale	2,820,516	19.49	54,971,856

Table 12. Insider trading of Synlogic, Inc. (MIRN) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-10-06	MIRN	Buy	857,142	7.00	5,999,994

Table 13. Insider trading of Tesaro, Inc. (TSRO) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-03-02	TSRO	Buy	68,302	55.83	3,813,573
2018-03-05	TSRO	Buy	61,437	59.06	3,628,714
2018-03-06	TSRO	Buy	15,793	59.81	944,658
2016-03-18	TSRO	Buy	1,420,858	35.19	49,999,993

Table 14. Insider trading of Oruka Therapeutics, Inc. (ABIO) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-02-26	ABIO	Sale	1,460,209	.50	731,564

Table 15. Insider trading of Surface Oncology, Inc. (SURF) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-04-23	SURF	Buy	133,333	15.00	1,999,995

Table 16. Insider trading of Epizyme, Inc. (EPZM) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-03-25	EPZM	Buy	28,231	7.98	225,283
2021-03-26	EPZM	Buy	34,486	7.88	271,922
2020-06-26	EPZM	Buy	62,019	16.03	994,164
2019-06-27	EPZM	Sale	52,473	12.43	652,134
2019-06-26	EPZM	Sale	52,472	12.85	674,160
2019-06-25	EPZM	Sale	52,472	13.31	698,664
2018-10-05	EPZM	Buy	416,667	9.00	3,750,003
2017-09-18	EPZM	Buy	200,000	15.25	3,050,000
2016-01-12	EPZM	Buy	1,111,111	9.00	9,999,999

Table 17. Insider trading of Ardelyx, Inc. (ARDX) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2025-06-16	ARDX	Buy	200,000	3.63	725,800
2025-06-09	ARDX	Buy	200,000	3.69	737,200
2025-05-15	ARDX	Buy	100,000	3.29	329,100
2025-05-02	ARDX	Buy	381,377	4.22	1,610,936
2025-02-24	ARDX	Buy	77,729	5.00	388,722
2025-01-21	ARDX	Buy	199,000	4.99	992,612
2024-11-13	ARDX	Buy	215,868	4.62	996,662
2022-11-17	ARDX	Buy	567,000	1.76	1,000,755
2022-11-17	ARDX	Buy	567,000	1.76	1,000,755
2022-11-17	ARDX	Buy	567,000	1.76	1,000,755
2020-12-10	ARDX	Buy	170,000	5.89	1,000,789
2020-06-24	ARDX	Buy	72,598	6.75	489,891
2020-06-25	ARDX	Buy	68,373	6.96	476,012
2020-06-22	ARDX	Buy	4,673	6.75	31,524
2016-07-18	ARDX	Buy	1,527,301	8.73	13,333,337
2016-01-13	ARDX	Buy	1,000,000	10.00	10,000,000
2015-06-05	ARDX	Buy	2,803,738	10.70	29,999,996

Table 18. Insider trading of Trevi Therapeutics, Inc. (TRVI) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-05-09	TRVI	Buy	2,500,000	10.00	25,000,000

Table 19. Insider trading of Interleukin Genetics Inc (ILIU) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-07-29	ILIU	Buy	20,120,724	.10	1,991,951

Table 20. Insider trading of Mirum Pharmaceuticals, Inc. (MIRM) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-07-22	MIRM	Buy	450,000	15.00	6,750,000

Table 21. Insider trading of Mersana Therapeutics, Inc. (MRSN) by Mott David M

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-04-07	MRSN	Buy	538,599	5.59	3,010,768
2019-03-05	MRSN	Buy	3,750,000	4.00	15,000,000
2017-07-03	MRSN	Buy	1,000,000	15.00	15,000,000

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Mott David M (Officer of Ardelyx, Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

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