Insider Trading History of Akkaraju Srinivas

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Akkaraju Srinivas since 2007. This trader's CIK number is 1253170. At the time of last reporting, Akkaraju Srinivas was the Officer of Alumis Inc.. (stock ticker symbol ALMS). Also see all insider trading activities at Alumis Inc..

Note that in the past AKKARAJU SRINIVAS also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Syros Pharmaceuticals, Inc. (SYRS) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2024	SYRS	0	$0	0	$0	4,000	$0
2023	SYRS	904,977	$3,999,998	0	$0	2,666	$0
2020	SYRS	0	$0	318,654	$3,855,993	0	$0
2019	SYRS	533,332	$3,999,990	0	$0	0	$0
2018	SYRS	209,424	$1,999,999	0	$0	0	$0
2017	SYRS	109,774	$991,557	0	$0	0	$0

Yearly summary of insider trading at Neurogene Inc. (NGNE) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2024	NGNE	48,770	$1,282,065	0	$0	0	$0

Yearly summary of insider trading at Paratek Pharmaceuticals, Inc. (TSPT) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2011	TSPT	0	$0	455,015	$2,142,570	0	$0

Yearly summary of insider trading at Lenz Therapeutics, Inc. (GRPH) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	GRPH	645,134	$3,718,843	0	$0	0	$0
2021	GRPH	420,310	$4,911,270	0	$0	0	$0

Yearly summary of insider trading at World Heart Corp (WHRT) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2010	WHRT	2,730,270	$7,000,001	0	$0	0	$0

Yearly summary of insider trading at Chinook Therapeutics, Inc. (KDNY) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2023	KDNY	0	$0	0	$0	3,300	$0
2021	KDNY	1,423,500	$19,507,830	0	$0	0	$0

Yearly summary of insider trading at Durata Therapeutics, Inc. (DRTX) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2012	DRTX	784,313	$7,058,817	0	$0	0	$0

Yearly summary of insider trading at Scholar Rock Holding Corp (SRRK) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2024	SRRK	0	$0	1,175,713	$35,271,390	0	$0
2023	SRRK	2,189,781	$14,999,999	0	$0	0	$0

Yearly summary of insider trading at Seagen Inc. (SGEN) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	SGEN	0	$0	8,500	$1,421,710	8,500	$170,510
2019	SGEN	0	$0	17,500	$2,099,737	17,500	$332,850
2018	SGEN	0	$0	0	$0	5,000	$41,900
2013	SGEN	0	$0	22,500	$814,172	22,500	$265,200
2010	SGEN	0	$0	0	$0	50,000	$368,300
2009	SGEN	10,405	$106,898	0	$0	0	$0
2008	SGEN	0	$0	654,585	$7,010,014	0	$0
2007	SGEN	0	$0	2,035,960	$17,533,274	0	$0

Yearly summary of insider trading at Cargo Therapeutics, Inc. (CRGX) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2024	CRGX	294,000	$4,998,000	0	$0	0	$0
2023	CRGX	666,666	$9,999,990	0	$0	0	$0

Yearly summary of insider trading at Mei Pharma, Inc. (MEIP) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2013	MEIP	0	$0	497,225	$3,341,685	0	$0

Yearly summary of insider trading at Atyr Pharma Inc (LIFE) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	LIFE	320,000	$4,480,000	0	$0	0	$0

Yearly summary of insider trading at Intercept Pharmaceuticals, Inc. (ICPT) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	ICPT	237,000	$5,036,730	0	$0	0	$0
2019	ICPT	5,207	$314,086	23,438	$3,018,345	3,500	$93,450
2016	ICPT	0	$0	0	$0	1,500	$32,250
2015	ICPT	0	$0	0	$0	2,250	$48,375
2014	ICPT	2,000	$330,072	3,250	$870,805	6,298	$84,118
2013	ICPT	0	$0	260	$14,436	1,298	$0
2012	ICPT	700,000	$10,500,000	0	$0	0	$0

Yearly summary of insider trading at Mineralys Therapeutics, Inc. (MLYS) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2025	MLYS	600,000	$8,100,000	0	$0	0	$0

Yearly summary of insider trading at Alumis Inc. (ALMS) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2025	ALMS	320,290	$1,517,458	0	$0	0	$0

Yearly summary of insider trading at Trimeris Inc (GEVA) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2012	GEVA	0	$0	684,556	$24,742,815	0	$0

Yearly summary of insider trading at Aravive, Inc. (ARAV) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	ARAV	133,333	$999,997	0	$0	0	$0
2018	ARAV	1,108,503	$2,027,636	0	$0	0	$0
2017	ARAV	1,547,896	$9,115,413	0	$0	0	$0
2016	ARAV	571,429	$7,000,005	0	$0	0	$0

Yearly summary of insider trading at Principia Biopharma Inc. (PRNB) by Akkaraju Srinivas

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	PRNB	175,000	$2,975,000	0	$0	0	$0

Insider trading activities at 18 companies by Akkaraju Srinivas:

1. Syros Pharmaceuticals, Inc. (SYRS)

2. Neurogene Inc. (NGNE)

3. Paratek Pharmaceuticals, Inc. (TSPT)

4. Lenz Therapeutics, Inc. (GRPH)

5. World Heart Corp (WHRT)

6. Chinook Therapeutics, Inc. (KDNY)

7. Durata Therapeutics, Inc. (DRTX)

8. Scholar Rock Holding Corp (SRRK)

9. Seagen Inc. (SGEN)

10. Cargo Therapeutics, Inc. (CRGX)

11. Mei Pharma, Inc. (MEIP)

12. Atyr Pharma Inc (LIFE)

13. Intercept Pharmaceuticals, Inc. (ICPT)

14. Mineralys Therapeutics, Inc. (MLYS)

15. Alumis Inc. (ALMS)

16. Trimeris Inc (GEVA)

17. Aravive, Inc. (ARAV)

18. Principia Biopharma Inc. (PRNB)

Table 1. Insider trading of Syros Pharmaceuticals, Inc. (SYRS) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2024-06-01	SYRS	Option Ex	4,000	.00	0
2023-12-21	SYRS	Buy	904,977	4.42	3,999,998
2023-09-16	SYRS	Option Ex	2,666	.00	0
2020-08-17	SYRS	Sale	744	13.00	9,672
2020-08-18	SYRS	Sale	158,583	13.10	2,076,802
2020-07-01	SYRS	Sale	4,627	11.02	50,966
2020-06-25	SYRS	Sale	54,972	11.15	612,827
2020-06-24	SYRS	Sale	48,775	11.07	539,792
2020-06-23	SYRS	Sale	50,953	11.11	565,934
2019-04-09	SYRS	Buy	533,332	7.50	3,999,990
2018-01-31	SYRS	Buy	209,424	9.55	1,999,999
2017-12-12	SYRS	Buy	14,774	9.40	138,875
2017-12-13	SYRS	Buy	68,400	8.97	613,548
2017-12-14	SYRS	Buy	26,600	8.99	239,134

Table 2. Insider trading of Neurogene Inc. (NGNE) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2024-11-26	NGNE	Buy	48,770	26.29	1,282,065

Table 3. Insider trading of Paratek Pharmaceuticals, Inc. (TSPT) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2011-07-19	TSPT	Sale	82,535	4.45	367,198
2011-07-18	TSPT	Sale	162,527	4.49	729,258
2011-07-13	TSPT	Sale	168,235	5.02	843,866
2011-07-14	TSPT	Sale	41,718	4.85	202,248

Table 4. Insider trading of Lenz Therapeutics, Inc. (GRPH) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-04-12	GRPH	Buy	350,000	4.08	1,428,000
2022-04-11	GRPH	Buy	74,464	4.07	303,068
2022-01-21	GRPH	Buy	100,000	8.99	899,000
2022-01-24	GRPH	Buy	23,000	8.70	200,099
2022-01-20	GRPH	Buy	43,105	8.92	384,496
2022-01-19	GRPH	Buy	54,565	9.24	504,180
2021-12-15	GRPH	Buy	22,329	10.19	227,532
2021-11-22	GRPH	Buy	201,685	10.15	2,047,102
2021-10-15	GRPH	Buy	2,300	12.49	28,727
2021-10-14	GRPH	Buy	3,100	12.50	38,750
2021-10-13	GRPH	Buy	45,400	13.22	600,188
2021-10-06	GRPH	Buy	61,475	13.83	850,199
2021-10-07	GRPH	Buy	9,021	14.94	134,773
2021-10-08	GRPH	Buy	75,000	13.12	983,999

Table 5. Insider trading of World Heart Corp (WHRT) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2010-10-19	WHRT	Buy	2,341,920	2.13	4,999,999
2010-01-26	WHRT	Buy	388,350	5.15	2,000,002

Table 6. Insider trading of Chinook Therapeutics, Inc. (KDNY) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2023-05-26	KDNY	Option Ex	3,300	.00	0
2021-11-15	KDNY	Buy	1,215,000	14.00	17,010,000
2021-08-18	KDNY	Buy	208,500	11.98	2,497,830

Table 7. Insider trading of Durata Therapeutics, Inc. (DRTX) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2012-07-24	DRTX	Buy	784,313	9.00	7,058,817

Table 8. Insider trading of Scholar Rock Holding Corp (SRRK) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2024-10-07	SRRK	Sale	1,175,713	30.00	35,271,390
2023-10-16	SRRK	Buy	2,189,781	6.85	14,999,999

Table 9. Insider trading of Seagen Inc. (SGEN) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-05-05	SGEN	Option Ex	8,500	20.06	170,510
2020-05-05	SGEN	Sale	8,500	167.26	1,421,710
2019-11-21	SGEN	Sale	17,500	119.98	2,099,737
2019-11-21	SGEN	Option Ex	17,500	19.02	332,850
2018-10-30	SGEN	Option Ex	5,000	8.38	41,900
2013-06-14	SGEN	Option Ex	5,000	8.38	41,900
2013-06-14	SGEN	Sale	5,000	32.75	163,750
2013-05-10	SGEN	Option Ex	17,500	12.76	223,300
2013-05-10	SGEN	Sale	17,500	37.17	650,422
2010-06-21	SGEN	Option Ex	50,000	7.37	368,300
2009-08-18	SGEN	Buy	4,905	11.47	56,260
2009-06-25	SGEN	Buy	5,500	9.21	50,638
2008-09-22	SGEN	Sale	18,601	12.79	237,906
2008-09-19	SGEN	Sale	37,011	12.74	471,520
2008-09-18	SGEN	Sale	20,839	12.71	264,863
2008-07-29	SGEN	Sale	95,688	10.85	1,038,214
2008-07-28	SGEN	Sale	21,232	10.36	219,963
2008-07-25	SGEN	Sale	148,136	10.81	1,601,350
2008-05-15	SGEN	Sale	98,758	10.14	1,001,406
2008-05-16	SGEN	Sale	42,059	10.39	436,993
2008-05-13	SGEN	Sale	50,896	10.06	512,013
2008-05-14	SGEN	Sale	121,365	10.10	1,225,786
2007-12-10	SGEN	Sale	20,960	12.63	264,724
2007-02-09	SGEN	Sale	2,015,000	8.57	17,268,550

Table 10. Insider trading of Cargo Therapeutics, Inc. (CRGX) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2024-05-30	CRGX	Buy	294,000	17.00	4,998,000
2023-11-14	CRGX	Buy	666,666	15.00	9,999,990

Table 11. Insider trading of Mei Pharma, Inc. (MEIP) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2013-02-19	MEIP	Sale	300,000	6.80	2,040,000
2013-02-15	MEIP	Sale	197,225	6.60	1,301,685

Table 12. Insider trading of Atyr Pharma Inc (LIFE) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-05-12	LIFE	Buy	320,000	14.00	4,480,000

Table 13. Insider trading of Intercept Pharmaceuticals, Inc. (ICPT) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-03-12	ICPT	Buy	147,000	21.29	3,129,630
2021-03-10	ICPT	Buy	90,000	21.19	1,907,100
2019-08-28	ICPT	Buy	5,207	60.32	314,086
2019-04-25	ICPT	Option Ex	3,500	26.70	93,450
2019-02-19	ICPT	Sale	23,438	128.78	3,018,345
2016-05-13	ICPT	Option Ex	1,500	21.50	32,250
2015-10-28	ICPT	Option Ex	1,250	21.50	26,875
2015-05-19	ICPT	Option Ex	1,000	21.50	21,500
2014-11-12	ICPT	Buy	2,000	165.04	330,072
2014-11-11	ICPT	Option Ex	2,500	21.50	53,750
2014-10-16	ICPT	Option Ex	324	.00	0
2014-07-16	ICPT	Option Ex	325	.00	0
2014-04-16	ICPT	Option Ex	324	.00	0
2014-01-16	ICPT	Sale	3,250	267.94	870,805
2014-01-16	ICPT	Option Ex	2,825	10.75	30,368
2013-12-18	ICPT	Sale	260	55.52	14,436
2013-10-16	ICPT	Option Ex	324	.00	0
2013-07-16	ICPT	Option Ex	325	.00	0
2013-04-16	ICPT	Option Ex	324	.00	0
2013-04-09	ICPT	Option Ex	325	.00	0
2012-10-16	ICPT	Buy	700,000	15.00	10,500,000

Table 14. Insider trading of Mineralys Therapeutics, Inc. (MLYS) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2025-03-13	MLYS	Buy	600,000	13.50	8,100,000

Table 15. Insider trading of Alumis Inc. (ALMS) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2025-05-02	ALMS	Buy	159,920	4.55	727,636
2025-05-05	ALMS	Buy	160,370	4.92	789,822

Table 16. Insider trading of Trimeris Inc (GEVA) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2012-06-26	GEVA	Sale	28,827	40.16	1,157,663
2012-06-27	GEVA	Sale	313,451	39.70	12,444,004
2012-03-19	GEVA	Sale	342,278	32.55	11,141,148

Table 17. Insider trading of Aravive, Inc. (ARAV) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-12-02	ARAV	Buy	133,333	7.50	999,997
2018-06-13	VSAR	Buy	53,018	2.13	112,928
2018-06-06	VSAR	Buy	660,681	1.74	1,149,584
2018-06-07	VSAR	Buy	163,224	1.85	301,964
2018-06-08	VSAR	Buy	231,580	2.00	463,160
2017-12-05	VSAR	Buy	42,895	2.00	85,790
2017-12-01	VSAR	Buy	419,700	2.13	893,961
2017-12-04	VSAR	Buy	513,872	2.21	1,135,657
2017-03-24	VSAR	Buy	571,429	12.25	7,000,005
2016-10-03	VSAR	Buy	571,429	12.25	7,000,005

Table 18. Insider trading of Principia Biopharma Inc. (PRNB) by Akkaraju Srinivas

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-09-18	PRNB	Buy	175,000	17.00	2,975,000

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Akkaraju Srinivas (Officer of Alumis Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

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