Insider Trading History of Baker Brothers Life Sciences Lp

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Baker Brothers Life Sciences Lp since 2015. This trader's CIK number is 1363364. At the time of last reporting, Baker Brothers Life Sciences Lp was the Officer of Madrigal Pharmaceuticals, Inc.. (stock ticker symbol MDGL). Also see all insider trading activities at Madrigal Pharmaceuticals, Inc..

Note that in the past Baker Brothers Life Sciences LP also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Madrigal Pharmaceuticals, Inc. (MDGL) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2025 MDGL 165,683 $61,875,548 0 $0 0 $0
2023 MDGL 424,685 $77,408,698 0 $0 0 $0

Yearly summary of insider trading at Beone Medicines Ltd. (BGNE) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2017 BGNE 176,056 $12,499,976 0 $0 0 $0

Yearly summary of insider trading at Talis Biomedical Corp (TLIS) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2021 TLIS 50,000 $218,250 0 $0 0 $0

Yearly summary of insider trading at Tscan Therapeutics, Inc. (TCRX) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2022 TCRX 1,359,792 $2,533,780 0 $0 0 $0

Yearly summary of insider trading at Incyte Corp (INCY) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2017 INCY 100,000 $13,200,000 0 $0 60,000 $435,600

Yearly summary of insider trading at Alexion Pharmaceuticals, Inc. (ALXN) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2017 ALXN 2,009,734 $234,362,596 0 $0 0 $0

Yearly summary of insider trading at Seagen Inc. (SGEN) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2021 SGEN 0 $0 394,895 $63,958,966 0 $0
2017 SGEN 0 $0 0 $0 20,000 $204,000
2016 SGEN 5,819,302 $236,397,681 0 $0 20,000 $83,600
2015 SGEN 9,422,008 $389,855,263 0 $0 20,000 $102,200

Yearly summary of insider trading at Acadia Pharmaceuticals Inc (ACAD) by Baker Brothers Life Sciences Lp

Insider Buying Insider Sales Option Exercises
Year Symbol Shares Value Shares Value Shares Value
2023 ACAD 896,522 $22,719,343 0 $0 25,000 $425,250


Insider trading activities at 8 companies by Baker Brothers Life Sciences Lp:

1. Madrigal Pharmaceuticals, Inc. (MDGL)

2. Beone Medicines Ltd. (BGNE)

3. Talis Biomedical Corp (TLIS)

4. Tscan Therapeutics, Inc. (TCRX)

5. Incyte Corp (INCY)

6. Alexion Pharmaceuticals, Inc. (ALXN)

7. Seagen Inc. (SGEN)

8. Acadia Pharmaceuticals Inc (ACAD)

Table 1. Insider trading of Madrigal Pharmaceuticals, Inc. (MDGL) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2025-08-18 MDGL Buy 68,618 363.32 24,930,017
2025-08-18 MDGL Buy 37,164 373.65 13,886,402
2025-08-20 MDGL Buy 59,901 384.95 23,059,129
2023-12-14 MDGL Buy 20,633 228.37 4,711,978
2023-12-13 MDGL Buy 81,159 220.73 17,914,226
2023-12-12 MDGL Buy 34,578 213.61 7,386,102
2023-11-20 MDGL Buy 20,709 186.18 3,855,580
2023-11-17 MDGL Buy 46,370 172.91 8,018,068
2023-11-21 MDGL Buy 64,350 187.22 12,047,349
2023-11-14 MDGL Buy 37,660 153.55 5,782,655
2023-11-13 MDGL Buy 69,839 141.51 9,883,196
2023-11-14 MDGL Buy 34,188 156.42 5,347,823
2023-11-15 MDGL Buy 15,199 161.97 2,461,721

Table 2. Insider trading of Beone Medicines Ltd. (BGNE) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2017-08-11 BGNE Buy 176,056 71.00 12,499,976

Table 3. Insider trading of Talis Biomedical Corp (TLIS) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2021-11-18 TLIS Buy 50,000 4.37 218,250

Table 4. Insider trading of Tscan Therapeutics, Inc. (TCRX) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2022-05-10 TCRX Buy 1,333,927 1.86 2,482,438
2022-05-11 TCRX Buy 25,865 1.99 51,342

Table 5. Insider trading of Incyte Corp (INCY) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2017-09-08 INCY Buy 100,000 132.00 13,200,000
2017-04-27 INCY Option Ex 60,000 7.26 435,600

Table 6. Insider trading of Alexion Pharmaceuticals, Inc. (ALXN) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2017-06-15 ALXN Buy 656,387 117.05 76,832,723
2017-06-14 ALXN Buy 4,392 118.00 518,256
2017-06-14 ALXN Buy 1,348,955 116.39 157,011,617

Table 7. Insider trading of Seagen Inc. (SGEN) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2021-11-30 SGEN Sale 301,444 162.21 48,896,628
2021-12-01 SGEN Sale 93,451 161.18 15,062,338
2017-05-15 SGEN Option Ex 20,000 10.20 204,000
2016-11-08 SGEN Buy 326,300 59.47 19,403,429
2016-11-07 SGEN Buy 56,200 58.74 3,301,356
2016-11-01 SGEN Buy 184,674 53.89 9,952,266
2016-11-02 SGEN Buy 466,619 56.04 26,151,195
2016-11-03 SGEN Buy 379,336 56.73 21,519,731
2016-11-03 SGEN Buy 198,433 56.35 11,180,905
2016-09-09 SGEN Buy 256,220 50.58 12,958,326
2016-09-12 SGEN Buy 49,889 50.64 2,526,378
2016-09-13 SGEN Buy 141,202 50.74 7,164,024
2016-09-07 SGEN Buy 59,560 48.29 2,875,914
2016-09-08 SGEN Buy 211,093 49.85 10,523,830
2016-09-06 SGEN Buy 143,363 45.59 6,536,062
2016-03-17 SGEN Buy 124,065 32.07 3,978,392
2016-03-14 SGEN Buy 118,941 33.77 4,016,518
2016-03-16 SGEN Buy 569,203 31.71 18,050,565
2016-03-15 SGEN Buy 661,093 31.85 21,057,134
2016-03-09 SGEN Buy 208,670 31.91 6,659,494
2016-03-10 SGEN Buy 290,231 32.35 9,390,424
2016-03-11 SGEN Buy 195,765 32.82 6,424,811
2016-03-08 SGEN Option Ex 20,000 4.18 83,600
2016-03-08 SGEN Buy 153,200 .00 0
2016-03-07 SGEN Buy 61,265 33.70 2,064,630
2016-03-04 SGEN Buy 288,058 32.09 9,242,917
2016-03-01 SGEN Buy 24,200 31.24 756,104
2016-02-29 SGEN Buy 251,722 30.45 7,663,676
2016-03-02 SGEN Buy 400,000 32.50 12,999,600
2015-11-18 SGEN Buy 14,638 43.42 635,552
2015-11-19 SGEN Buy 133,073 43.93 5,845,364
2015-11-20 SGEN Buy 181,647 43.93 7,980,297
2015-11-10 SGEN Buy 9,400 44.00 413,600
2015-11-09 SGEN Buy 507,300 43.57 22,102,553
2015-11-06 SGEN Buy 417,924 41.91 17,514,776
2015-09-11 SGEN Buy 4,212,787 42.49 179,009,745
2015-09-14 SGEN Buy 320,438 45.76 14,663,883
2015-09-15 SGEN Buy 626,259 47.64 29,837,483
2015-05-19 SGEN Buy 214,129 40.91 8,759,375
2015-05-20 SGEN Buy 374,298 42.07 15,745,219
2015-05-21 SGEN Buy 362,459 43.46 15,753,555
2015-05-11 SGEN Option Ex 20,000 5.11 102,200
2015-05-05 SGEN Buy 530,952 34.49 18,312,003
2015-05-07 SGEN Buy 47,717 37.11 1,770,873
2015-05-06 SGEN Buy 453,995 36.22 16,441,882
2015-03-09 SGEN Buy 275,717 34.66 9,555,248
2015-03-10 SGEN Buy 9,319 34.59 322,362
2015-03-03 SGEN Buy 425,220 34.84 14,815,090
2015-03-04 SGEN Buy 23,621 34.81 822,152
2015-02-24 SGEN Buy 217,465 33.68 7,324,656
2015-02-25 SGEN Buy 63,650 35.03 2,229,595

Table 8. Insider trading of Acadia Pharmaceuticals Inc (ACAD) by Baker Brothers Life Sciences Lp

Trade Date Symbol Trade Type Shares Price ($) Value ($)
2023-05-24 ACAD Buy 553,263 25.48 14,096,587
2023-05-22 ACAD Buy 134,206 24.63 3,305,493
2023-05-23 ACAD Buy 209,053 25.43 5,317,263
2023-05-23 ACAD Option Ex 25,000 17.01 425,250

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Baker Brothers Life Sciences Lp (Officer of Madrigal Pharmaceuticals, Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.



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