1. Corporate Officers - F
2. Florence Anthony A. Jr.

Insider Trading History of Florence Anthony A. Jr.

The following table details the insider trading activities (stock purchases, stock sales, and stock option exercises) of Florence Anthony A. Jr. since 2014. This trader's CIK number is 1559827. At the time of last reporting, Florence Anthony A. Jr. was the Officer of Mbx Biosciences, Inc.. (stock ticker symbol MBX). Also see all insider trading activities at Mbx Biosciences, Inc..

Note that in the past Florence Anthony A. Jr. also reported insider trading activities as an insider of the following companies:

Yearly summary of insider trading at Adaptimmune Therapeutics Plc (ADAP) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	ADAP	7,500,000	$5,002,500	0	$0	0	$0
2018	ADAP	22,839,672	$40,012,335	0	$0	0	$0
2017	ADAP	12,870,000	$9,009,000	0	$0	0	$0

Yearly summary of insider trading at Robinhood Markets, Inc. (HOOD) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	HOOD	0	$0	4,034	$49,238	0	$0

Yearly summary of insider trading at Inozyme Pharma, Inc. (INZY) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	INZY	250,000	$4,000,000	0	$0	0	$0

Yearly summary of insider trading at Enliven Therapeutics, Inc. (IMRA) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	IMRA	0	$0	31,916	$72,194	0	$0

Yearly summary of insider trading at Loxo Oncology, Inc. (LOXO) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2014	LOXO	230,769	$2,999,997	0	$0	0	$0

Yearly summary of insider trading at Regulus Therapeutics Inc. (RGLS) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	RGLS	4,398,602	$2,735,930	0	$0	0	$0
2019	RGLS	1,136,704	$1,227,640	0	$0	0	$0

Yearly summary of insider trading at Arcellx, Inc. (ACLX) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	ACLX	0	$0	179	$5,501	0	$0

Yearly summary of insider trading at Casper Sleep Inc. (CSPR) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	CSPR	1,250,000	$15,000,000	0	$0	0	$0

Yearly summary of insider trading at Nkarta, Inc. (NKTK) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	NKTK	666,666	$11,999,988	0	$0	0	$0

Yearly summary of insider trading at Arca Biopharma, Inc. (ABIO) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	ABIO	0	$0	1,460,209	$731,564	0	$0

Yearly summary of insider trading at Ardelyx, Inc. (ARDX) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	ARDX	2,527,301	$23,333,337	0	$0	0	$0

Yearly summary of insider trading at Surface Oncology, Inc. (SURF) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2018	SURF	133,333	$1,999,995	0	$0	0	$0

Yearly summary of insider trading at Eargo, Inc. (EAR) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	EAR	311,111	$5,599,998	0	$0	0	$0

Yearly summary of insider trading at Trevi Therapeutics, Inc. (TRVI) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	TRVI	3,580,526	$6,802,999	0	$0	0	$0
2021	TRVI	1,851,852	$0	0	$0	0	$0
2020	TRVI	0	$0	564	$1,500	0	$0
2019	TRVI	2,500,000	$25,000,000	0	$0	0	$0

Yearly summary of insider trading at Interleukin Genetics Inc (ILIU) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	ILIU	20,120,724	$1,991,951	0	$0	0	$0
2014	ILIU	19,868,965	$1,986,896	0	$0	0	$0

Yearly summary of insider trading at Cvent Inc (CVT) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	CVT	0	$0	829	$22,616	0	$0
2014	CVT	0	$0	250	$6,639	0	$0

Yearly summary of insider trading at Akouos, Inc. (AKUS) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	AKUS	588,235	$9,999,995	0	$0	0	$0

Yearly summary of insider trading at Aveo Pharmaceuticals, Inc. (AVEO) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	AVEO	1,428,571	$7,499,997	0	$0	0	$0
2019	AVEO	4,347,827	$4,956,522	0	$0	0	$0
2018	AVEO	4,296,865	$8,662,202	0	$0	0	$0
2017	AVEO	6,000,000	$3,000,000	0	$0	0	$0

Yearly summary of insider trading at Savara Inc (SVRA) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2023	SVRA	333,333	$999,999	0	$0	0	$0

Yearly summary of insider trading at Mbx Biosciences, Inc. (MBX) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2024	MBX	500,000	$8,000,000	0	$0	0	$0

Yearly summary of insider trading at Achaogen, Inc. (AKAO) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	AKAO	500,000	$6,750,000	0	$0	0	$0

Yearly summary of insider trading at Genocea Biosciences, Inc. (GNCA) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2022	GNCA	0	$0	10,376,936	$750,066	0	$0
2020	GNCA	3,151,260	$7,090,335	0	$0	0	$0
2019	GNCA	12,805,411	$14,685,631	0	$0	0	$0

Yearly summary of insider trading at Tracon Pharmaceuticals, Inc. (TCON) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2016	TCON	869,565	$4,999,998	0	$0	0	$0
2015	TCON	500,000	$5,000,000	0	$0	0	$0

Yearly summary of insider trading at Marker Therapeutics, Inc. (MRKR) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	MRKR	5,714,285	$9,999,998	0	$0	0	$0

Yearly summary of insider trading at Metacrine, Inc. (MTCR) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2021	MTCR	0	$0	497,270	$489,102	0	$0
2020	MTCR	769,230	$9,999,990	0	$0	0	$0

Yearly summary of insider trading at Appian Corp (APPN) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2017	APPN	0	$0	3,390,136	$66,073,749	0	$0

Yearly summary of insider trading at Synlogic, Inc. (MIRN) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2015	MIRN	857,142	$5,999,994	0	$0	0	$0

Yearly summary of insider trading at Korro Bio, Inc. (KRRO) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2024	KRRO	17,857	$999,992	0	$0	0	$0

Yearly summary of insider trading at Mirum Pharmaceuticals, Inc. (MIRM) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2019	MIRM	450,000	$6,750,000	0	$0	0	$0

Yearly summary of insider trading at Mersana Therapeutics, Inc. (MRSN) by Florence Anthony A. Jr.

		Insider Buying		Insider Sales		Option Exercises
Year	Symbol	Shares	Value	Shares	Value	Shares	Value
2020	MRSN	0	$0	20,914	$177,769	0	$0
2017	MRSN	1,000,000	$15,000,000	0	$0	0	$0

Insider trading activities at 30 companies by Florence Anthony A. Jr.:

1. Adaptimmune Therapeutics Plc (ADAP)

2. Robinhood Markets, Inc. (HOOD)

3. Inozyme Pharma, Inc. (INZY)

4. Enliven Therapeutics, Inc. (IMRA)

5. Loxo Oncology, Inc. (LOXO)

6. Regulus Therapeutics Inc. (RGLS)

7. Arcellx, Inc. (ACLX)

8. Casper Sleep Inc. (CSPR)

9. Nkarta, Inc. (NKTK)

10. Arca Biopharma, Inc. (ABIO)

11. Ardelyx, Inc. (ARDX)

12. Surface Oncology, Inc. (SURF)

13. Eargo, Inc. (EAR)

14. Trevi Therapeutics, Inc. (TRVI)

15. Interleukin Genetics Inc (ILIU)

16. Cvent Inc (CVT)

17. Akouos, Inc. (AKUS)

18. Aveo Pharmaceuticals, Inc. (AVEO)

19. Savara Inc (SVRA)

20. Mbx Biosciences, Inc. (MBX)

21. Achaogen, Inc. (AKAO)

22. Genocea Biosciences, Inc. (GNCA)

23. Tracon Pharmaceuticals, Inc. (TCON)

24. Marker Therapeutics, Inc. (MRKR)

25. Metacrine, Inc. (MTCR)

26. Appian Corp (APPN)

27. Synlogic, Inc. (MIRN)

28. Korro Bio, Inc. (KRRO)

29. Mirum Pharmaceuticals, Inc. (MIRM)

30. Mersana Therapeutics, Inc. (MRSN)

Table 1. Insider trading of Adaptimmune Therapeutics Plc (ADAP) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-01-24	ADAP	Buy	7,500,000	.67	5,002,500
2018-09-07	ADAP	Buy	15,000,000	1.67	25,005,000
2018-03-26	ADAP	Buy	571,164	1.90	1,087,496
2018-03-27	ADAP	Buy	6,000,000	1.92	11,502,000
2018-03-21	ADAP	Buy	104,844	1.81	189,872
2018-03-23	ADAP	Buy	294,090	1.95	572,299
2018-03-22	ADAP	Buy	869,574	1.90	1,655,668
2017-03-27	ADAP	Buy	12,870,000	.70	9,009,000

Table 2. Insider trading of Robinhood Markets, Inc. (HOOD) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-05-03	HOOD	Sale	1,952	10.06	19,641
2022-01-31	HOOD	Sale	2,082	14.22	29,597

Table 3. Insider trading of Inozyme Pharma, Inc. (INZY) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-28	INZY	Buy	250,000	16.00	4,000,000

Table 4. Insider trading of Enliven Therapeutics, Inc. (IMRA) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-01-06	IMRA	Sale	10,257	2.17	22,206
2022-01-05	IMRA	Sale	8,200	2.25	18,441
2022-01-04	IMRA	Sale	13,459	2.34	31,547

Table 5. Insider trading of Loxo Oncology, Inc. (LOXO) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2014-08-06	LOXO	Buy	230,769	13.00	2,999,997

Table 6. Insider trading of Regulus Therapeutics Inc. (RGLS) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-12-04	RGLS	Buy	4,398,602	.62	2,735,930
2019-05-07	RGLS	Buy	1,136,704	1.08	1,227,640

Table 7. Insider trading of Arcellx, Inc. (ACLX) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-12-21	ACLX	Sale	179	30.74	5,501

Table 8. Insider trading of Casper Sleep Inc. (CSPR) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-02-10	CSPR	Buy	1,250,000	12.00	15,000,000

Table 9. Insider trading of Nkarta, Inc. (NKTK) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-07-14	NKTK	Buy	666,666	18.00	11,999,988

Table 10. Insider trading of Arca Biopharma, Inc. (ABIO) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-02-26	ABIO	Sale	1,460,209	.50	731,564

Table 11. Insider trading of Ardelyx, Inc. (ARDX) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-07-18	ARDX	Buy	1,527,301	8.73	13,333,337
2016-01-13	ARDX	Buy	1,000,000	10.00	10,000,000

Table 12. Insider trading of Surface Oncology, Inc. (SURF) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2018-04-23	SURF	Buy	133,333	15.00	1,999,995

Table 13. Insider trading of Eargo, Inc. (EAR) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-10-20	EAR	Buy	311,111	18.00	5,599,998

Table 14. Insider trading of Trevi Therapeutics, Inc. (TRVI) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-04-11	TRVI	Buy	3,580,526	1.90	6,802,999
2021-10-18	TRVI	Buy	1,851,852	.00	0
2020-04-03	TRVI	Sale	564	2.66	1,500
2019-05-09	TRVI	Buy	2,500,000	10.00	25,000,000

Table 15. Insider trading of Interleukin Genetics Inc (ILIU) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-07-29	ILIU	Buy	20,120,724	.10	1,991,951
2014-12-23	ILIU	Buy	19,868,965	.10	1,986,896

Table 16. Insider trading of Cvent Inc (CVT) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-06-11	CVT	Sale	441	26.65	11,752
2015-05-19	CVT	Sale	388	28.00	10,864
2014-12-02	CVT	Sale	129	27.28	3,519
2014-09-08	CVT	Sale	121	25.79	3,120

Table 17. Insider trading of Akouos, Inc. (AKUS) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-06-30	AKUS	Buy	588,235	17.00	9,999,995

Table 18. Insider trading of Aveo Pharmaceuticals, Inc. (AVEO) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-06-19	AVEO	Buy	1,428,571	5.25	7,499,997
2019-04-08	AVEO	Buy	4,347,827	1.14	4,956,522
2018-12-21	AVEO	Buy	300,000	1.50	448,500
2018-12-20	AVEO	Buy	200,000	1.63	326,000
2018-12-11	AVEO	Buy	61,200	1.98	121,114
2018-12-07	AVEO	Buy	117,100	1.98	232,326
2018-12-10	AVEO	Buy	26,000	1.98	51,584
2018-12-06	AVEO	Buy	27,300	1.99	54,408
2018-11-28	AVEO	Buy	24,500	1.99	48,828
2018-11-30	AVEO	Buy	71,900	1.98	142,074
2018-11-20	AVEO	Buy	170,000	1.98	336,090
2018-11-15	AVEO	Buy	340,000	1.86	632,060
2018-11-16	AVEO	Buy	350,000	1.85	649,250
2018-11-19	AVEO	Buy	510,000	1.88	956,760
2018-08-21	AVEO	Buy	663,716	2.26	1,499,998
2018-07-18	AVEO	Buy	200,000	1.95	390,600
2018-07-19	AVEO	Buy	50,600	2.00	101,149
2018-06-28	AVEO	Buy	187,130	2.10	392,785
2018-06-27	AVEO	Buy	5,295	2.15	11,384
2018-05-30	AVEO	Buy	275	2.15	591
2018-05-08	AVEO	Buy	70,873	2.13	151,242
2018-04-06	AVEO	Buy	685,676	2.24	1,537,285
2018-04-09	AVEO	Buy	32,100	2.43	78,099
2018-04-10	AVEO	Buy	203,200	2.46	500,075
2017-03-28	AVEO	Buy	6,000,000	.50	3,000,000

Table 19. Insider trading of Savara Inc (SVRA) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2023-07-17	SVRA	Buy	333,333	3.00	999,999

Table 20. Insider trading of Mbx Biosciences, Inc. (MBX) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2024-09-16	MBX	Buy	500,000	16.00	8,000,000

Table 21. Insider trading of Achaogen, Inc. (AKAO) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-12-19	AKAO	Buy	500,000	13.50	6,750,000

Table 22. Insider trading of Genocea Biosciences, Inc. (GNCA) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2022-05-25	GNCA	Sale	4,445,093	.08	364,497
2022-05-24	GNCA	Sale	5,931,843	.07	385,569
2020-07-24	GNCA	Buy	3,151,260	2.25	7,090,335
2019-06-24	GNCA	Buy	2,857,142	3.50	9,999,997
2019-02-14	GNCA	Buy	9,948,269	.47	4,685,634

Table 23. Insider trading of Tracon Pharmaceuticals, Inc. (TCON) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2016-11-29	TCON	Buy	869,565	5.75	4,999,998
2015-02-04	TCON	Buy	500,000	10.00	5,000,000

Table 24. Insider trading of Marker Therapeutics, Inc. (MRKR) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-03-16	MRKR	Buy	5,714,285	1.75	9,999,998

Table 25. Insider trading of Metacrine, Inc. (MTCR) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2021-12-10	MTCR	Sale	37,570	1.32	49,629
2021-12-22	MTCR	Sale	459,700	.96	439,473
2020-09-18	MTCR	Buy	769,230	13.00	9,999,990

Table 26. Insider trading of Appian Corp (APPN) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2017-11-27	APPN	Sale	569,620	19.49	11,101,893
2017-11-20	APPN	Sale	2,820,516	19.49	54,971,856

Table 27. Insider trading of Synlogic, Inc. (MIRN) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2015-10-06	MIRN	Buy	857,142	7.00	5,999,994

Table 28. Insider trading of Korro Bio, Inc. (KRRO) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2024-04-22	KRRO	Buy	17,857	56.00	999,992

Table 29. Insider trading of Mirum Pharmaceuticals, Inc. (MIRM) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2019-07-22	MIRM	Buy	450,000	15.00	6,750,000

Table 30. Insider trading of Mersana Therapeutics, Inc. (MRSN) by Florence Anthony A. Jr.

Trade Date	Symbol	Trade Type	Shares	Price ($)	Value ($)
2020-04-13	MRSN	Sale	20,914	8.50	177,769
2017-07-03	MRSN	Buy	1,000,000	15.00	15,000,000

Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Florence Anthony A. Jr. (Officer of Mbx Biosciences, Inc. at the time of this reporting) see the Securities and Exchange Commission (SEC) website.

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