- Corporate Officers - O
- Opaleye Management Inc.
Insider Trading History of Opaleye Management Inc.
The following table details the insider trading activities
(stock purchases, stock sales, and stock option exercises) of Opaleye Management Inc. since 2015.
This trader's CIK number is 1595855.
At the time of last reporting, Opaleye Management Inc. was the Officer of Codexis, Inc.. (stock ticker symbol CDXS).
Also see all insider trading activities at Codexis, Inc..
Note that in the past
Opaleye Management Inc. also reported insider trading activities as an insider of the following companies:
Yearly summary of insider trading at Protara Therapeutics, Inc. (TARA) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2024 | TARA | 0 | $0 | 703,460 | $1,746,165 | 0 | $0 |
| 2022 | TARA | 58,067 | $261,560 | 15,473 | $41,947 | 0 | $0 |
| 2021 | TARA | 91,528 | $608,667 | 0 | $0 | 0 | $0 |
| 2020 | TARA | 350,000 | $5,861,000 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Codexis, Inc. (CDXS) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2025 | CDXS | 3,580,000 | $8,849,760 | 0 | $0 | 0 | $0 |
| 2024 | CDXS | 1,271,000 | $3,822,929 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Harrow, Inc. (HROW) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2025 | HROW | 0 | $0 | 60,000 | $1,927,864 | 0 | $0 |
| 2024 | HROW | 170,000 | $1,843,734 | 0 | $0 | 0 | $0 |
| 2023 | HROW | 45,000 | $492,799 | 0 | $0 | 0 | $0 |
| 2022 | HROW | 490,000 | $4,967,597 | 0 | $0 | 0 | $0 |
| 2021 | HROW | 219,584 | $1,836,736 | 0 | $0 | 0 | $0 |
| 2020 | HROW | 466,316 | $2,410,742 | 0 | $0 | 0 | $0 |
| 2016 | HROW | 45,000 | $164,250 | 0 | $0 | 0 | $0 |
| 2015 | HROW | 37,801 | $298,908 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Sanuwave Health, Inc. (SNWV) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2025 | SNWV | 7,998 | $203,877 | 0 | $0 | 0 | $0 |
| 2024 | SNWV | 27,868 | $438,895 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Tracon Pharmaceuticals, Inc. (TCON) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2023 | TCON | 174,508 | $240,821 | 0 | $0 | 0 | $0 |
| 2022 | TCON | 1,147,500 | $1,742,071 | 1,539 | $2,216 | 0 | $0 |
| 2021 | TCON | 411,450 | $1,040,357 | 0 | $0 | 0 | $0 |
| 2020 | TCON | 1,345,529 | $5,922,925 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Tela Bio, Inc. (TELA) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2022 | TELA | 511,475 | $3,947,023 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Eton Pharmaceuticals, Inc. (ETON) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2025 | ETON | 7,930 | $125,484 | 0 | $0 | 0 | $0 |
| 2024 | ETON | 179,570 | $1,018,819 | 0 | $0 | 0 | $0 |
| 2021 | ETON | 0 | $0 | 1,579,900 | $10,147,666 | 0 | $0 |
| 2020 | ETON | 400,000 | $2,800,000 | 0 | $0 | 0 | $0 |
Yearly summary of insider trading at Ocular Therapeutix, Inc (OCUL) by Opaleye Management Inc.
| | Insider Buying | Insider Sales | Option Exercises |
|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
|---|
| 2020 | OCUL | 35,000 | $137,935 | 0 | $0 | 0 | $0 |
Insider trading activities at 8 companies by Opaleye Management Inc.:
1. Protara Therapeutics, Inc. (TARA)
2. Codexis, Inc. (CDXS)
3. Harrow, Inc. (HROW)
4. Sanuwave Health, Inc. (SNWV)
5. Tracon Pharmaceuticals, Inc. (TCON)
6. Tela Bio, Inc. (TELA)
7. Eton Pharmaceuticals, Inc. (ETON)
8. Ocular Therapeutix, Inc (OCUL)
Table 1. Insider trading of Protara Therapeutics, Inc. (TARA) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2024-09-12 | TARA | Sale | 126,301 | 1.71 | 215,848 |
| 2024-09-11 | TARA | Sale | 32,600 | 1.71 | 55,876 |
| 2024-09-09 | TARA | Sale | 36,492 | 1.90 | 69,152 |
| 2024-09-10 | TARA | Sale | 25,500 | 1.77 | 45,109 |
| 2024-07-16 | TARA | Sale | 11,396 | 2.44 | 27,829 |
| 2024-07-09 | TARA | Sale | 8,497 | 2.21 | 18,812 |
| 2024-07-10 | TARA | Sale | 18,061 | 2.31 | 41,684 |
| 2024-07-11 | TARA | Sale | 47,993 | 2.40 | 115,327 |
| 2024-07-01 | TARA | Sale | 8,288 | 2.12 | 17,595 |
| 2024-06-27 | TARA | Sale | 46,574 | 2.26 | 105,164 |
| 2024-06-28 | TARA | Sale | 17,994 | 2.08 | 37,337 |
| 2024-06-25 | TARA | Sale | 12,725 | 2.26 | 28,733 |
| 2024-05-30 | TARA | Sale | 9,230 | 2.94 | 27,117 |
| 2024-05-31 | TARA | Sale | 5,824 | 2.90 | 16,895 |
| 2024-05-21 | TARA | Sale | 33,000 | 3.06 | 100,848 |
| 2024-05-22 | TARA | Sale | 9,800 | 3.01 | 29,517 |
| 2024-05-17 | TARA | Sale | 70,885 | 3.19 | 226,406 |
| 2024-05-09 | TARA | Sale | 30,600 | 3.09 | 94,523 |
| 2024-05-10 | TARA | Sale | 151,700 | 3.11 | 472,393 |
| 2022-12-30 | TARA | Sale | 15,473 | 2.71 | 41,947 |
| 2022-09-14 | TARA | Buy | 16,600 | 3.98 | 66,068 |
| 2022-09-15 | TARA | Buy | 7,300 | 3.80 | 27,740 |
| 2022-04-07 | TARA | Buy | 2,345 | 4.74 | 11,122 |
| 2022-04-08 | TARA | Buy | 7,791 | 4.80 | 37,365 |
| 2022-01-28 | TARA | Buy | 24,031 | 4.96 | 119,265 |
| 2021-12-28 | TARA | Buy | 7,091 | 6.36 | 45,091 |
| 2021-12-29 | TARA | Buy | 4,500 | 6.98 | 31,410 |
| 2021-12-27 | TARA | Buy | 36,700 | 6.53 | 239,724 |
| 2021-12-23 | TARA | Buy | 1,300 | 6.60 | 8,580 |
| 2021-12-20 | TARA | Buy | 703 | 6.49 | 4,562 |
| 2021-12-16 | TARA | Buy | 7,563 | 6.41 | 48,486 |
| 2021-12-17 | TARA | Buy | 2,790 | 6.60 | 18,414 |
| 2021-11-18 | TARA | Buy | 15,206 | 6.98 | 106,137 |
| 2021-11-17 | TARA | Buy | 9,118 | 6.98 | 63,643 |
| 2021-11-04 | TARA | Buy | 6,557 | 6.50 | 42,620 |
| 2020-09-30 | TARA | Buy | 50,000 | 16.00 | 800,000 |
| 2020-09-24 | "TARA" | Buy | 300,000 | 16.87 | 5,061,000 |
Table 2. Insider trading of Codexis, Inc. (CDXS) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2025-07-31 | CDXS | Buy | 84,220 | 2.68 | 225,709 |
| 2025-08-04 | CDXS | Buy | 780 | 2.83 | 2,211 |
| 2025-07-29 | CDXS | Buy | 8,422 | 2.82 | 23,750 |
| 2025-07-30 | CDXS | Buy | 1,578 | 2.79 | 4,410 |
| 2025-07-18 | CDXS | Buy | 100,000 | 2.82 | 282,000 |
| 2025-06-27 | CDXS | Buy | 100,000 | 2.39 | 239,000 |
| 2025-05-23 | CDXS | Buy | 2,320,000 | 2.36 | 5,475,200 |
| 2025-05-28 | CDXS | Buy | 5,000 | 2.36 | 11,800 |
| 2025-04-30 | CDXS | Buy | 25,000 | 2.31 | 57,650 |
| 2025-05-01 | CDXS | Buy | 20,000 | 2.32 | 46,440 |
| 2025-04-15 | CDXS | Buy | 25,000 | 2.23 | 55,725 |
| 2025-04-16 | CDXS | Buy | 70,000 | 2.13 | 148,889 |
| 2025-04-17 | CDXS | Buy | 45,000 | 2.09 | 94,185 |
| 2025-04-08 | CDXS | Buy | 100,000 | 1.98 | 198,400 |
| 2025-04-03 | CDXS | Buy | 75,000 | 2.30 | 172,725 |
| 2025-04-02 | CDXS | Buy | 5,000 | 2.46 | 12,275 |
| 2025-04-01 | CDXS | Buy | 35,000 | 2.48 | 86,765 |
| 2025-03-13 | CDXS | Buy | 85,000 | 2.54 | 216,155 |
| 2025-03-06 | CDXS | Buy | 100,000 | 2.61 | 261,400 |
| 2025-03-04 | CDXS | Buy | 55,000 | 2.64 | 145,420 |
| 2025-03-05 | CDXS | Buy | 10,000 | 2.69 | 26,880 |
| 2025-02-28 | CDXS | Buy | 147,649 | 2.99 | 441,175 |
| 2025-03-03 | CDXS | Buy | 47,351 | 2.81 | 133,151 |
| 2025-02-12 | CDXS | Buy | 15,000 | 4.00 | 59,940 |
| 2025-02-11 | CDXS | Buy | 12,500 | 4.11 | 51,400 |
| 2025-02-10 | CDXS | Buy | 22,500 | 4.18 | 94,140 |
| 2025-01-30 | CDXS | Buy | 20,000 | 4.49 | 89,780 |
| 2025-01-31 | CDXS | Buy | 45,000 | 4.29 | 193,185 |
| 2024-10-25 | CDXS | Buy | 25,000 | 2.91 | 72,725 |
| 2024-09-25 | CDXS | Buy | 5,000 | 2.86 | 14,290 |
| 2024-09-24 | CDXS | Buy | 80,000 | 2.94 | 234,880 |
| 2024-09-20 | CDXS | Buy | 1,055,000 | 3.01 | 3,175,550 |
| 2024-09-23 | CDXS | Buy | 45,000 | 2.94 | 132,480 |
| 2024-09-18 | CDXS | Buy | 61,000 | 3.16 | 193,004 |
Table 3. Insider trading of Harrow, Inc. (HROW) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2025-06-10 | HROW | Sale | 15,000 | 30.80 | 462,030 |
| 2025-06-09 | HROW | Sale | 15,204 | 30.37 | 461,791 |
| 2025-06-04 | HROW | Sale | 1,796 | 30.02 | 53,906 |
| 2025-06-03 | HROW | Sale | 3,000 | 30.04 | 90,117 |
| 2025-03-18 | HROW | Sale | 5,000 | 29.64 | 148,200 |
| 2025-01-22 | HROW | Sale | 20,000 | 35.59 | 711,820 |
| 2024-04-25 | HROW | Buy | 20,000 | 9.97 | 199,400 |
| 2024-04-23 | HROW | Buy | 11,715 | 10.29 | 120,547 |
| 2024-04-24 | HROW | Buy | 8,285 | 10.15 | 84,092 |
| 2024-04-19 | HROW | Buy | 29,400 | 10.56 | 310,405 |
| 2024-03-28 | HROW | Buy | 50,000 | 12.82 | 641,000 |
| 2024-03-20 | HROW | Buy | 50,600 | 9.65 | 488,290 |
| 2023-11-15 | HROW | Buy | 25,000 | 8.03 | 200,725 |
| 2023-09-19 | HROW | Buy | 14,017 | 14.65 | 205,363 |
| 2023-09-20 | HROW | Buy | 5,983 | 14.49 | 86,711 |
| 2022-12-14 | HROW | Buy | 431,183 | 10.52 | 4,536,045 |
| 2022-09-28 | HROW | Buy | 11,085 | 9.78 | 108,355 |
| 2022-04-12 | HROW | Buy | 28,557 | 6.75 | 192,731 |
| 2022-04-13 | HROW | Buy | 12,832 | 6.76 | 86,782 |
| 2022-01-28 | HROW | Buy | 6,343 | 6.89 | 43,684 |
| 2021-08-19 | HROW | Buy | 52,500 | 8.45 | 443,362 |
| 2021-08-17 | HROW | Buy | 26,000 | 8.57 | 222,716 |
| 2021-08-18 | HROW | Buy | 46,500 | 8.64 | 401,992 |
| 2021-07-19 | HROW | Buy | 5,869 | 6.97 | 40,895 |
| 2021-07-20 | HROW | Buy | 4,925 | 7.20 | 35,460 |
| 2021-07-21 | HROW | Buy | 9,206 | 7.60 | 69,937 |
| 2021-06-17 | HROW | Buy | 11,262 | 8.32 | 93,699 |
| 2021-06-18 | HROW | Buy | 63,322 | 8.35 | 528,675 |
| 2020-12-21 | HROW | Buy | 53,459 | 5.24 | 280,071 |
| 2020-12-22 | HROW | Buy | 16,557 | 5.20 | 86,013 |
| 2020-12-18 | HROW | Buy | 36,400 | 5.31 | 193,393 |
| 2020-07-10 | HROW | Buy | 45,000 | 4.98 | 223,965 |
| 2020-07-11 | HROW | Buy | 46,800 | 4.96 | 231,940 |
| 2020-07-12 | HROW | Buy | 20,900 | 4.98 | 104,165 |
| 2020-07-09 | HROW | Buy | 30,000 | 4.83 | 144,840 |
| 2020-07-07 | HROW | Buy | 41,300 | 5.18 | 214,016 |
| 2020-07-08 | HROW | Buy | 65,000 | 4.99 | 324,610 |
| 2020-06-19 | HROW | Buy | 35,000 | 5.58 | 195,405 |
| 2020-06-02 | HROW | Buy | 19,400 | 5.69 | 110,347 |
| 2020-06-04 | HROW | Buy | 10,000 | 5.79 | 57,859 |
| 2020-06-03 | HROW | Buy | 20,600 | 5.74 | 118,305 |
| 2020-05-22 | HROW | Buy | 13,804 | 5.04 | 69,530 |
| 2020-05-20 | HROW | Buy | 1,500 | 4.48 | 6,726 |
| 2020-05-21 | HROW | Buy | 10,596 | 4.68 | 49,557 |
| 2016-03-11 | IMMY | Buy | 45,000 | 3.65 | 164,250 |
| 2015-06-30 | IMMY | Buy | 35,000 | 7.90 | 276,500 |
| 2015-05-19 | IMMY | Buy | 2,801 | 8.00 | 22,408 |
Table 4. Insider trading of Sanuwave Health, Inc. (SNWV) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2025-04-29 | SNWV | Buy | 7,998 | 25.49 | 203,877 |
| 2024-10-31 | SNWVD | Buy | 9,868 | 16.29 | 160,759 |
| 2024-10-30 | SNWVD | Buy | 2,000 | 17.50 | 35,000 |
| 2024-11-01 | SNWVD | Buy | 16,000 | 15.20 | 243,136 |
Table 5. Insider trading of Tracon Pharmaceuticals, Inc. (TCON) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2023-03-09 | TCON | Buy | 174,508 | 1.38 | 240,821 |
| 2022-12-06 | TCON | Sale | 1,539 | 1.44 | 2,216 |
| 2022-10-18 | TCON | Buy | 12,500 | 1.65 | 20,625 |
| 2022-09-29 | TCON | Buy | 9,400 | 1.74 | 16,374 |
| 2022-09-27 | TCON | Buy | 1,700 | 1.69 | 2,876 |
| 2022-09-22 | TCON | Buy | 17,311 | 1.73 | 29,948 |
| 2022-09-20 | TCON | Buy | 10,000 | 1.85 | 18,520 |
| 2022-09-19 | TCON | Buy | 5,000 | 1.87 | 9,365 |
| 2022-07-26 | TCON | Buy | 2,254 | 1.72 | 3,876 |
| 2022-07-15 | TCON | Buy | 11,826 | 1.78 | 21,073 |
| 2022-07-14 | TCON | Buy | 7,187 | 1.81 | 13,022 |
| 2022-06-24 | TCON | Buy | 11,419 | 1.39 | 15,895 |
| 2022-06-21 | TCON | Buy | 841,989 | 1.31 | 1,105,531 |
| 2022-05-10 | TCON | Buy | 9,700 | 1.76 | 17,033 |
| 2022-04-22 | TCON | Buy | 7,100 | 1.98 | 14,058 |
| 2022-04-25 | TCON | Buy | 10,777 | 2.18 | 23,493 |
| 2022-04-22 | TCON | Buy | 42,000 | 2.24 | 93,954 |
| 2022-04-14 | TCON | Buy | 12,696 | 2.50 | 31,727 |
| 2022-04-13 | TCON | Buy | 7,345 | 2.50 | 18,362 |
| 2022-04-11 | TCON | Buy | 9,100 | 2.42 | 22,022 |
| 2022-04-12 | TCON | Buy | 18,098 | 2.48 | 44,828 |
| 2022-03-16 | "TCON" | Buy | 2,235 | 2.20 | 4,917 |
| 2022-01-28 | TCON | Buy | 500 | 2.20 | 1,100 |
| 2022-01-21 | TCON | Buy | 35,000 | 2.19 | 76,825 |
| 2022-01-24 | TCON | Buy | 17,363 | 2.05 | 35,611 |
| 2022-01-20 | TCON | Buy | 21,312 | 2.25 | 47,952 |
| 2022-01-19 | TCON | Buy | 23,688 | 2.24 | 53,084 |
| 2021-12-29 | TCON | Buy | 52,325 | 2.51 | 131,388 |
| 2021-12-27 | TCON | Buy | 87,325 | 2.92 | 255,076 |
| 2021-12-28 | TCON | Buy | 20,125 | 2.63 | 52,948 |
| 2021-12-15 | TCON | Buy | 21,964 | 2.43 | 53,284 |
| 2021-12-14 | TCON | Buy | 42,000 | 2.53 | 106,344 |
| 2021-12-13 | TCON | Buy | 15,204 | 2.64 | 40,153 |
| 2021-12-03 | TCON | Buy | 89,274 | 2.29 | 204,883 |
| 2021-12-06 | TCON | Buy | 22,733 | 2.26 | 51,467 |
| 2021-12-01 | TCON | Buy | 50,000 | 2.40 | 120,150 |
| 2021-12-02 | TCON | Buy | 10,500 | 2.35 | 24,664 |
| 2020-12-22 | "TCON" | Buy | 496,277 | 8.06 | 3,999,992 |
| 2020-10-21 | TCON | Buy | 8,656 | 4.40 | 38,060 |
| 2020-09-24 | TCON | Buy | 21,534 | 4.44 | 95,654 |
| 2020-09-23 | TCON | Buy | 57,200 | 4.83 | 276,447 |
| 2020-09-04 | TCON | Buy | 9,058 | 2.88 | 26,132 |
| 2020-09-09 | TCON | Buy | 47,500 | 3.47 | 164,777 |
| 2020-09-02 | TCON | Buy | 119,800 | 2.35 | 282,009 |
| 2020-09-01 | TCON | Buy | 40,000 | 2.04 | 81,760 |
| 2020-08-28 | TCON | Buy | 60,000 | 1.78 | 106,980 |
| 2020-08-27 | TCON | Buy | 183,354 | 1.71 | 312,985 |
| 2020-08-31 | TCON | Buy | 302,150 | 1.78 | 538,129 |
Table 6. Insider trading of Tela Bio, Inc. (TELA) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2022-11-03 | TELA | Buy | 20,262 | 7.81 | 158,286 |
| 2022-10-11 | TELA | Buy | 16,000 | 8.00 | 128,000 |
| 2022-09-23 | TELA | Buy | 6,804 | 7.99 | 54,391 |
| 2022-09-19 | TELA | Buy | 18,000 | 8.09 | 145,583 |
| 2022-09-15 | TELA | Buy | 4,158 | 8.10 | 33,679 |
| 2022-09-16 | TELA | Buy | 2,372 | 8.08 | 19,172 |
| 2022-08-16 | TELA | Buy | 5,221 | 8.10 | 42,284 |
| 2022-08-16 | TELA | Buy | 315,000 | 8.00 | 2,520,000 |
| 2022-08-10 | TELA | Buy | 11,979 | 8.52 | 102,085 |
| 2022-08-01 | TELA | Buy | 4,979 | 7.96 | 39,632 |
| 2022-07-22 | TELA | Buy | 5,200 | 8.02 | 41,709 |
| 2022-07-21 | TELA | Buy | 10,333 | 8.05 | 83,211 |
| 2022-07-20 | TELA | Buy | 5,100 | 8.08 | 41,192 |
| 2022-07-01 | "TELA" | Buy | 200 | 7.00 | 1,400 |
| 2022-06-29 | "TELA" | Buy | 2 | 6.99 | 13 |
| 2022-06-30 | "TELA" | Buy | 3,565 | 7.00 | 24,955 |
| 2022-06-22 | TELA | Buy | 2,400 | 6.99 | 16,776 |
| 2022-06-10 | "TELA" | Buy | 2,400 | 6.50 | 15,600 |
| 2022-06-22 | "TELA" | Buy | 50,000 | 6.50 | 325,000 |
| 2022-06-10 | TELA | Buy | 27,500 | 5.60 | 154,055 |
Table 7. Insider trading of Eton Pharmaceuticals, Inc. (ETON) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2025-06-10 | ETON | Buy | 7,930 | 15.82 | 125,484 |
| 2024-10-23 | ETON | Buy | 10,000 | 7.98 | 79,810 |
| 2024-10-04 | ETON | Buy | 16,852 | 6.77 | 114,104 |
| 2024-10-08 | ETON | Buy | 33,970 | 7.03 | 238,775 |
| 2024-10-07 | ETON | Buy | 11,248 | 7.22 | 81,255 |
| 2024-09-11 | ETON | Buy | 50,000 | 4.75 | 237,500 |
| 2024-09-10 | ETON | Buy | 57,500 | 4.65 | 267,375 |
| 2021-11-17 | ETON | Sale | 25,000 | 4.67 | 116,724 |
| 2021-11-15 | ETON | Sale | 3,000 | 4.80 | 14,405 |
| 2021-11-16 | ETON | Sale | 12,438 | 4.86 | 60,473 |
| 2021-11-05 | ETON | Sale | 167,701 | 6.30 | 1,056,684 |
| 2021-11-08 | ETON | Sale | 52,661 | 6.10 | 321,284 |
| 2021-11-03 | ETON | Sale | 116,500 | 6.53 | 760,861 |
| 2021-11-04 | ETON | Sale | 85,700 | 6.44 | 551,650 |
| 2021-10-08 | ETON | Sale | 43,692 | 5.00 | 218,460 |
| 2021-10-11 | ETON | Sale | 34,101 | 5.01 | 170,709 |
| 2021-10-12 | ETON | Sale | 87,307 | 5.06 | 441,511 |
| 2021-08-06 | ETON | Sale | 345,000 | 5.84 | 2,014,800 |
| 2021-08-05 | ETON | Sale | 155,500 | 5.85 | 910,141 |
| 2021-08-04 | ETON | Sale | 104,000 | 5.75 | 598,104 |
| 2021-06-15 | ETON | Sale | 105,000 | 8.07 | 847,350 |
| 2021-05-27 | ETON | Sale | 126,000 | 8.49 | 1,069,740 |
| 2021-05-26 | ETON | Sale | 68,300 | 8.57 | 585,331 |
| 2021-05-25 | ETON | Sale | 48,000 | 8.53 | 409,439 |
| 2020-10-16 | ETON | Buy | 400,000 | 7.00 | 2,800,000 |
Table 8. Insider trading of Ocular Therapeutix, Inc (OCUL) by Opaleye Management Inc.
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|
| 2020-01-02 | OCUL | Buy | 15,000 | 3.90 | 58,515 |
| 2019-12-30 | OCUL | Buy | 20,000 | 3.97 | 79,420 |
Insider trading activities including stock purchases, stock sales, and option exercises
listed in the above table cannot be completely guaranteed as to their accuracy.
For more information regarding the trades made by Opaleye Management Inc.
(Officer of Codexis, Inc. at the time of this reporting) see
the Securities and Exchange Commission (SEC) website.