The following table details the insider trading activities
(stock purchases, stock sales, and stock option exercises) of Crooke Stanley T since 2006.
This trader's CIK number is 897667.
At the time of last reporting, Crooke Stanley T was the Exec Chairman of the Board of Ionis Pharmaceuticals Inc. (stock ticker symbol IONS).
Also see all insider trading activities at Ionis Pharmaceuticals Inc.
| Insider Buying | Insider Sales | Option Exercises | |||||
|---|---|---|---|---|---|---|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
| 2021 | IONS | 0 | $0 | 103,333 | $6,410,953 | 51,628 | $0 |
| 2020 | IONS | 0 | $0 | 225,391 | $11,438,022 | 70,640 | $1,103,600 |
| 2019 | IONS | 0 | $0 | 187,904 | $12,487,872 | 220,837 | $6,454,598 |
| 2018 | IONS | 0 | $0 | 63,511 | $3,146,772 | 78,296 | $558,630 |
| 2017 | IONS | 0 | $0 | 191,957 | $9,613,063 | 205,834 | $1,677,643 |
| 2016 | IONS | 0 | $0 | 139,901 | $5,757,119 | 151,161 | $1,259,809 |
| 2015 | IONS | 0 | $0 | 153,404 | $9,094,873 | 161,775 | $1,479,359 |
| 2014 | IONS | 0 | $0 | 179,527 | $6,769,452 | 185,260 | $2,335,234 |
| 2013 | IONS | 0 | $0 | 699,670 | $20,142,650 | 501,521 | $5,720,311 |
| 2012 | IONS | 0 | $0 | 191,536 | $2,798,976 | 191,536 | $1,084,208 |
| 2011 | IONS | 0 | $0 | 81,100 | $556,546 | 81,100 | $470,380 |
| 2010 | IONS | 0 | $0 | 52,000 | $542,600 | 52,000 | $500,500 |
| 2009 | IONS | 0 | $0 | 264,035 | $2,732,935 | 264,035 | $1,844,669 |
| 2008 | IONS | 0 | $0 | 42,473 | $568,749 | 42,473 | $454,680 |
| 2007 | IONS | 0 | $0 | 129,851 | $2,244,908 | 131,951 | $1,195,927 |
| 2006 | IONS | 0 | $0 | 50,000 | $573,850 | 0 | $0 |
| Insider Buying | Insider Sales | Option Exercises | |||||
|---|---|---|---|---|---|---|---|
| Year | Symbol | Shares | Value | Shares | Value | Shares | Value |
| 2012 | RGLS | 750,000 | $3,000,000 | 0 | $0 | 0 | $0 |
1. Ionis Pharmaceuticals Inc (IONS)
2. Regulus Therapeutics Inc. (RGLS)
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|---|---|---|---|---|
| 2021-01-26 | IONS | Sale | 28,333 | 63.73 | 1,805,803 |
| 2021-01-21 | IONS | Sale | 35,000 | 61.09 | 2,138,150 |
| 2021-01-22 | IONS | Sale | 40,000 | 61.67 | 2,467,000 |
| 2021-01-15 | IONS | Option Ex | 51,628 | .00 | 0 |
| 2020-12-17 | IONS | Sale | 1,407 | 50.50 | 71,053 |
| 2020-12-15 | IONS | Sale | 39,000 | 49.77 | 1,941,225 |
| 2020-12-07 | IONS | Sale | 11,000 | 51.69 | 568,535 |
| 2020-11-25 | IONS | Option Ex | 12,990 | 39.87 | 517,911 |
| 2020-11-25 | IONS | Sale | 12,990 | 50.05 | 650,149 |
| 2020-11-23 | IONS | Option Ex | 12,100 | 39.87 | 482,426 |
| 2020-11-23 | IONS | Sale | 12,100 | 50.05 | 605,665 |
| 2020-11-24 | IONS | Option Ex | 2,590 | 39.87 | 103,263 |
| 2020-11-24 | IONS | Sale | 2,590 | 50.83 | 131,649 |
| 2020-09-21 | IONS | Sale | 2,000 | 50.18 | 100,360 |
| 2020-09-22 | IONS | Sale | 50,000 | 50.41 | 2,520,450 |
| 2020-06-24 | IONS | Sale | 5,000 | 58.80 | 294,000 |
| 2020-06-25 | IONS | Sale | 9,914 | 60.11 | 595,910 |
| 2020-06-19 | IONS | Sale | 10,000 | 58.33 | 583,250 |
| 2020-06-17 | IONS | Sale | 17,000 | 58.08 | 987,292 |
| 2020-03-25 | IONS | Sale | 16,000 | 47.00 | 752,000 |
| 2020-03-19 | IONS | Sale | 16,000 | 45.25 | 724,032 |
| 2020-03-17 | IONS | Sale | 20,390 | 44.75 | 912,452 |
| 2020-01-15 | IONS | Option Ex | 42,960 | .00 | 0 |
| 2019-08-21 | IONS | Option Ex | 10,000 | 39.87 | 398,700 |
| 2019-08-20 | IONS | Option Ex | 12,000 | 39.87 | 478,439 |
| 2019-08-21 | IONS | Sale | 10,000 | 72.15 | 721,500 |
| 2019-08-20 | IONS | Sale | 12,000 | 71.00 | 852,000 |
| 2019-07-18 | IONS | Option Ex | 10,000 | 39.87 | 398,700 |
| 2019-07-18 | IONS | Sale | 10,000 | 70.25 | 702,510 |
| 2019-04-16 | IONS | Sale | 21,000 | 84.70 | 1,778,763 |
| 2019-04-15 | IONS | Sale | 11,000 | 85.25 | 937,750 |
| 2019-04-16 | IONS | Option Ex | 21,000 | 26.31 | 552,573 |
| 2019-04-15 | IONS | Option Ex | 11,000 | 12.76 | 140,305 |
| 2019-02-25 | IONS | Option Ex | 40,000 | 39.87 | 1,594,800 |
| 2019-02-26 | IONS | Option Ex | 37,000 | 39.87 | 1,475,190 |
| 2019-02-25 | IONS | Sale | 40,000 | 60.07 | 2,402,720 |
| 2019-02-26 | IONS | Sale | 37,000 | 61.53 | 2,276,795 |
| 2019-02-13 | IONS | Sale | 46,904 | 60.03 | 2,815,834 |
| 2019-02-13 | IONS | Option Ex | 46,904 | 30.19 | 1,415,891 |
| 2019-01-15 | IONS | Option Ex | 32,933 | .00 | 0 |
| 2018-04-17 | IONS | Option Ex | 13,962 | 12.76 | 178,085 |
| 2018-04-17 | IONS | Sale | 13,962 | 44.40 | 619,912 |
| 2018-01-15 | IONS | Option Ex | 31,334 | .00 | 0 |
| 2018-01-15 | IONS | Sale | 16,549 | 51.76 | 856,576 |
| 2018-01-08 | IONS | Sale | 11,000 | 52.01 | 572,110 |
| 2018-01-08 | IONS | Option Ex | 11,000 | 12.76 | 140,305 |
| 2018-01-03 | IONS | Sale | 22,000 | 49.92 | 1,098,174 |
| 2018-01-03 | IONS | Option Ex | 22,000 | 10.92 | 240,240 |
| 2017-10-13 | IONS | Option Ex | 16,500 | 10.97 | 181,005 |
| 2017-10-13 | IONS | Sale | 16,500 | 59.46 | 981,090 |
| 2017-10-02 | IONS | Sale | 16,500 | 52.00 | 858,000 |
| 2017-10-04 | IONS | Sale | 11,000 | 54.23 | 596,475 |
| 2017-10-04 | IONS | Option Ex | 11,000 | 10.97 | 120,670 |
| 2017-10-02 | IONS | Option Ex | 16,500 | 10.97 | 181,005 |
| 2017-07-20 | IONS | Option Ex | 11,000 | 10.97 | 120,670 |
| 2017-07-20 | IONS | Sale | 11,000 | 55.35 | 608,850 |
| 2017-07-17 | IONS | Sale | 16,500 | 52.45 | 865,425 |
| 2017-07-17 | IONS | Option Ex | 16,500 | 10.97 | 181,005 |
| 2017-07-03 | IONS | Sale | 16,500 | 52.16 | 860,640 |
| 2017-07-03 | IONS | Option Ex | 16,500 | 9.73 | 160,545 |
| 2017-04-25 | IONS | Option Ex | 16,500 | 7.25 | 119,625 |
| 2017-04-25 | IONS | Sale | 16,500 | 47.81 | 788,865 |
| 2017-04-19 | IONS | Option Ex | 5,500 | 7.25 | 39,875 |
| 2017-04-19 | IONS | Sale | 5,500 | 43.25 | 237,875 |
| 2017-04-13 | IONS | Sale | 11,000 | 41.30 | 454,299 |
| 2017-04-12 | IONS | Sale | 11,000 | 40.07 | 440,770 |
| 2017-04-13 | IONS | Option Ex | 11,000 | 8.26 | 90,893 |
| 2017-04-12 | IONS | Option Ex | 11,000 | 8.77 | 96,470 |
| 2017-03-02 | IONS | Option Ex | 12,100 | 8.77 | 106,117 |
| 2017-03-02 | IONS | Sale | 12,100 | 51.05 | 617,705 |
| 2017-01-17 | IONS | Sale | 15,957 | 46.29 | 738,649 |
| 2017-01-15 | IONS | Option Ex | 29,834 | .00 | 0 |
| 2017-01-10 | IONS | Option Ex | 13,200 | 8.77 | 115,764 |
| 2017-01-10 | IONS | Sale | 13,200 | 49.25 | 650,100 |
| 2017-01-04 | IONS | Sale | 7,700 | 50.10 | 385,770 |
| 2017-01-03 | IONS | Sale | 11,000 | 48.05 | 528,550 |
| 2017-01-04 | IONS | Option Ex | 7,700 | 8.77 | 67,529 |
| 2017-01-03 | IONS | Option Ex | 11,000 | 8.77 | 96,470 |
| 2016-11-09 | IONS | Option Ex | 22,000 | 9.68 | 213,004 |
| 2016-11-10 | IONS | Option Ex | 11,000 | 8.77 | 96,470 |
| 2016-11-09 | IONS | Sale | 22,000 | 36.50 | 803,000 |
| 2016-11-10 | IONS | Sale | 11,000 | 41.23 | 453,475 |
| 2016-10-05 | IONS | Option Ex | 11,000 | 10.29 | 113,189 |
| 2016-10-05 | IONS | Sale | 11,000 | 36.61 | 402,710 |
| 2016-09-27 | IONS | Sale | 22,000 | 36.03 | 792,769 |
| 2016-09-27 | IONS | Option Ex | 22,000 | 10.29 | 226,379 |
| 2016-09-21 | IONS | Sale | 22,000 | 35.50 | 781,000 |
| 2016-09-21 | IONS | Option Ex | 22,000 | 10.29 | 226,379 |
| 2016-04-06 | IONS | Option Ex | 11,000 | 10.29 | 113,189 |
| 2016-04-06 | IONS | Sale | 11,000 | 46.12 | 507,375 |
| 2016-03-31 | IONS | Sale | 11,000 | 40.73 | 448,085 |
| 2016-03-31 | IONS | Option Ex | 11,000 | 10.02 | 110,242 |
| 2016-01-15 | IONS | Option Ex | 24,661 | .00 | 0 |
| 2016-01-19 | IONS | Sale | 13,401 | 41.46 | 555,605 |
| 2016-01-05 | IONS | Sale | 5,500 | 62.10 | 341,550 |
| 2016-01-05 | IONS | Option Ex | 5,500 | 9.76 | 53,652 |
| 2016-01-04 | IONS | Option Ex | 11,000 | 9.76 | 107,305 |
| 2016-01-04 | IONS | Sale | 11,000 | 61.05 | 671,550 |
| 2015-10-23 | ISIS | Sale | 27,500 | 44.57 | 1,225,675 |
| 2015-10-23 | ISIS | Option Ex | 27,500 | 10.06 | 276,595 |
| 2015-10-21 | ISIS | Sale | 16,500 | 43.00 | 709,500 |
| 2015-10-21 | ISIS | Option Ex | 16,500 | 10.59 | 174,685 |
| 2015-07-06 | ISIS | Sale | 6,175 | 57.01 | 352,018 |
| 2015-07-06 | ISIS | Option Ex | 6,175 | 10.24 | 63,262 |
| 2015-07-01 | ISIS | Option Ex | 6,175 | 10.24 | 63,262 |
| 2015-07-01 | ISIS | Sale | 6,175 | 57.56 | 355,439 |
| 2015-04-07 | ISIS | Option Ex | 22,377 | 10.24 | 229,252 |
| 2015-04-07 | ISIS | Sale | 22,377 | 63.07 | 1,411,339 |
| 2015-04-01 | ISIS | Option Ex | 21,623 | 10.24 | 221,527 |
| 2015-04-01 | ISIS | Sale | 21,623 | 61.93 | 1,339,155 |
| 2015-01-27 | ISIS | Option Ex | 11,000 | 10.24 | 112,694 |
| 2015-01-27 | ISIS | Sale | 11,000 | 72.93 | 802,186 |
| 2015-01-16 | ISIS | Sale | 9,054 | 67.96 | 615,346 |
| 2015-01-15 | ISIS | Option Ex | 17,425 | .00 | 0 |
| 2015-01-09 | ISIS | Option Ex | 11,000 | 10.24 | 112,694 |
| 2015-01-09 | ISIS | Sale | 11,000 | 73.57 | 809,269 |
| 2015-01-06 | ISIS | Option Ex | 11,000 | 10.24 | 112,694 |
| 2015-01-07 | ISIS | Sale | 11,000 | 68.05 | 748,528 |
| 2015-01-06 | ISIS | Sale | 11,000 | 66.04 | 726,418 |
| 2015-01-07 | ISIS | Option Ex | 11,000 | 10.24 | 112,694 |
| 2014-10-23 | ISIS | Option Ex | 14,600 | 11.65 | 170,133 |
| 2014-10-23 | ISIS | Sale | 14,600 | 42.22 | 616,412 |
| 2014-10-01 | ISIS | Sale | 22,000 | 37.91 | 834,042 |
| 2014-10-03 | ISIS | Option Ex | 14,000 | 11.85 | 165,830 |
| 2014-10-03 | ISIS | Sale | 14,000 | 39.49 | 552,818 |
| 2014-10-01 | ISIS | Option Ex | 22,000 | 11.65 | 256,366 |
| 2014-08-13 | ISIS | Sale | 17,100 | 35.45 | 606,263 |
| 2014-08-13 | ISIS | Option Ex | 17,100 | 12.87 | 220,077 |
| 2014-08-01 | ISIS | Option Ex | 16,000 | 12.87 | 205,920 |
| 2014-08-01 | ISIS | Sale | 16,000 | 30.52 | 488,400 |
| 2014-07-01 | ISIS | Option Ex | 17,500 | 13.40 | 234,552 |
| 2014-07-01 | ISIS | Sale | 17,500 | 35.56 | 622,282 |
| 2014-06-19 | ISIS | Sale | 11,000 | 35.10 | 386,111 |
| 2014-06-19 | ISIS | Option Ex | 11,000 | 14.47 | 159,170 |
| 2014-06-10 | ISIS | Option Ex | 11,000 | 14.47 | 159,170 |
| 2014-06-10 | ISIS | Sale | 11,000 | 33.45 | 368,005 |
| 2014-04-02 | ISIS | Option Ex | 8,800 | 14.47 | 127,336 |
| 2014-04-02 | ISIS | Sale | 8,800 | 43.65 | 384,102 |
| 2014-01-16 | ISIS | Sale | 3,527 | 47.08 | 166,054 |
| 2014-01-15 | ISIS | Option Ex | 9,260 | .00 | 0 |
| 2014-01-08 | ISIS | Option Ex | 12,500 | 14.47 | 180,875 |
| 2014-01-08 | ISIS | Sale | 12,500 | 40.05 | 500,650 |
| 2014-01-02 | ISIS | Option Ex | 31,500 | 14.47 | 455,805 |
| 2014-01-02 | ISIS | Sale | 31,500 | 39.50 | 1,244,313 |
| 2013-09-20 | ISIS | Sale | 8,740 | 35.90 | 313,748 |
| 2013-09-19 | ISIS | Sale | 50,000 | 35.07 | 1,753,600 |
| 2013-09-20 | ISIS | Option Ex | 8,740 | 11.12 | 97,188 |
| 2013-09-19 | ISIS | Option Ex | 50,000 | 11.12 | 556,000 |
| 2013-09-10 | ISIS | Sale | 30,000 | 31.65 | 949,440 |
| 2013-09-09 | ISIS | Sale | 26,615 | 30.41 | 809,495 |
| 2013-09-09 | ISIS | Option Ex | 26,615 | 11.12 | 295,958 |
| 2013-09-11 | ISIS | Sale | 20,000 | 31.18 | 623,620 |
| 2013-07-23 | ISIS | Option Ex | 11,500 | 11.12 | 127,879 |
| 2013-07-23 | ISIS | Sale | 11,500 | 30.00 | 345,000 |
| 2013-07-18 | ISIS | Option Ex | 20,000 | 11.12 | 222,399 |
| 2013-07-22 | ISIS | Sale | 20,000 | 30.86 | 617,100 |
| 2013-07-22 | ISIS | Option Ex | 20,000 | 13.96 | 279,200 |
| 2013-07-19 | ISIS | Sale | 22,200 | 30.82 | 684,181 |
| 2013-07-18 | ISIS | Sale | 20,000 | 30.11 | 602,220 |
| 2013-07-19 | ISIS | Option Ex | 22,200 | 15.38 | 341,436 |
| 2013-07-16 | ISIS | Sale | 6,000 | 33.31 | 199,842 |
| 2013-07-17 | ISIS | Option Ex | 13,300 | 13.56 | 180,348 |
| 2013-07-15 | ISIS | Sale | 30,000 | 33.81 | 1,014,179 |
| 2013-07-16 | ISIS | Option Ex | 6,000 | 11.12 | 66,720 |
| 2013-07-15 | ISIS | Option Ex | 30,000 | 11.12 | 333,600 |
| 2013-07-17 | ISIS | Sale | 13,300 | 31.71 | 421,782 |
| 2013-07-11 | ISIS | Sale | 30,000 | 32.00 | 960,090 |
| 2013-07-12 | ISIS | Sale | 30,000 | 33.14 | 994,140 |
| 2013-07-12 | ISIS | Option Ex | 30,000 | 12.54 | 376,200 |
| 2013-07-10 | ISIS | Sale | 30,000 | 30.05 | 901,440 |
| 2013-07-11 | ISIS | Option Ex | 30,000 | 15.38 | 461,400 |
| 2013-07-10 | ISIS | Option Ex | 30,000 | 15.38 | 461,400 |
| 2013-07-05 | ISIS | Option Ex | 24,180 | 15.38 | 371,888 |
| 2013-07-09 | ISIS | Sale | 30,000 | 30.04 | 901,290 |
| 2013-07-08 | ISIS | Sale | 54,992 | 25.16 | 1,383,873 |
| 2013-07-09 | ISIS | Option Ex | 30,000 | 15.38 | 461,400 |
| 2013-07-08 | ISIS | Option Ex | 5,008 | 15.38 | 77,023 |
| 2013-07-05 | ISIS | Sale | 24,180 | 30.02 | 725,762 |
| 2013-07-01 | ISIS | Sale | 10,000 | 28.17 | 281,700 |
| 2013-06-28 | ISIS | Sale | 20,683 | 27.23 | 563,198 |
| 2013-06-27 | ISIS | Sale | 20,000 | 27.85 | 557,000 |
| 2013-06-28 | ISIS | Option Ex | 20,683 | 8.25 | 170,572 |
| 2013-06-27 | ISIS | Option Ex | 20,000 | 6.81 | 136,200 |
| 2013-06-26 | ISIS | Sale | 30,000 | 26.90 | 807,030 |
| 2013-06-25 | ISIS | Sale | 30,000 | 28.09 | 842,790 |
| 2013-06-26 | ISIS | Option Ex | 20,000 | 6.81 | 136,200 |
| 2013-06-24 | ISIS | Sale | 30,000 | 25.19 | 755,700 |
| 2013-06-25 | ISIS | Option Ex | 30,000 | 6.81 | 204,300 |
| 2013-04-24 | ISIS | Sale | 10,000 | 22.12 | 221,200 |
| 2013-04-23 | ISIS | Sale | 30,000 | 22.10 | 662,910 |
| 2013-04-22 | ISIS | Sale | 30,000 | 20.99 | 629,700 |
| 2013-04-22 | ISIS | Option Ex | 20,000 | 7.26 | 145,200 |
| 2013-04-19 | ISIS | Sale | 30,000 | 20.01 | 600,180 |
| 2013-04-19 | ISIS | Option Ex | 30,000 | 7.26 | 217,800 |
| 2013-01-15 | ISIS | Option Ex | 3,295 | .00 | 0 |
| 2013-01-16 | ISIS | Sale | 1,460 | 14.00 | 20,440 |
| 2012-09-20 | ISIS | Option Ex | 30,000 | 6.04 | 181,350 |
| 2012-09-19 | ISIS | Option Ex | 30,000 | 5.25 | 157,500 |
| 2012-09-21 | ISIS | Sale | 29,462 | 14.06 | 414,235 |
| 2012-09-20 | ISIS | Sale | 30,000 | 15.01 | 450,240 |
| 2012-09-19 | ISIS | Sale | 30,000 | 14.81 | 444,450 |
| 2012-09-21 | ISIS | Option Ex | 29,462 | 6.84 | 201,520 |
| 2012-09-13 | ISIS | Option Ex | 27,074 | 5.25 | 142,138 |
| 2012-09-13 | ISIS | Sale | 27,074 | 14.55 | 393,926 |
| 2012-09-05 | ISIS | Sale | 15,000 | 14.82 | 222,345 |
| 2012-09-06 | ISIS | Option Ex | 30,000 | 5.51 | 165,450 |
| 2012-09-04 | ISIS | Sale | 30,000 | 14.11 | 423,240 |
| 2012-09-05 | ISIS | Option Ex | 15,000 | 5.25 | 78,750 |
| 2012-09-04 | ISIS | Option Ex | 30,000 | 5.25 | 157,500 |
| 2012-09-06 | ISIS | Sale | 30,000 | 15.02 | 450,540 |
| 2011-12-21 | ISIS | Option Ex | 17,800 | 5.80 | 103,240 |
| 2011-12-21 | ISIS | Sale | 17,800 | 6.92 | 123,176 |
| 2011-12-20 | ISIS | Sale | 28,700 | 6.87 | 197,169 |
| 2011-12-19 | ISIS | Sale | 18,100 | 6.86 | 124,166 |
| 2011-12-20 | ISIS | Option Ex | 28,700 | 5.80 | 166,460 |
| 2011-12-19 | ISIS | Option Ex | 18,100 | 5.80 | 104,980 |
| 2011-12-16 | ISIS | Sale | 16,500 | 6.79 | 112,035 |
| 2011-12-16 | ISIS | Option Ex | 16,500 | 5.80 | 95,700 |
| 2010-12-27 | ISIS | Sale | 20,000 | 10.42 | 208,400 |
| 2010-12-27 | ISIS | Option Ex | 20,000 | 9.62 | 192,500 |
| 2010-12-29 | ISIS | Sale | 12,000 | 10.31 | 123,780 |
| 2010-12-29 | ISIS | Option Ex | 12,000 | 9.62 | 115,500 |
| 2010-12-22 | ISIS | Option Ex | 16,000 | 9.62 | 154,000 |
| 2010-12-23 | ISIS | Option Ex | 4,000 | 9.62 | 38,500 |
| 2010-12-22 | ISIS | Sale | 16,000 | 10.52 | 168,320 |
| 2010-12-23 | ISIS | Sale | 4,000 | 10.53 | 42,100 |
| 2009-12-30 | ISIS | Sale | 6,535 | 11.06 | 72,309 |
| 2009-12-30 | ISIS | Option Ex | 6,535 | 6.81 | 44,503 |
| 2009-12-22 | ISIS | Sale | 20,000 | 10.13 | 202,600 |
| 2009-12-22 | ISIS | Option Ex | 20,000 | 6.81 | 136,260 |
| 2009-12-16 | ISIS | Sale | 23,465 | 10.11 | 237,113 |
| 2009-12-15 | ISIS | Sale | 26,535 | 10.03 | 266,146 |
| 2009-12-16 | ISIS | Option Ex | 23,465 | 6.81 | 159,867 |
| 2009-12-15 | ISIS | Option Ex | 26,535 | 6.81 | 180,782 |
| 2009-12-11 | ISIS | Option Ex | 20,000 | 6.81 | 136,260 |
| 2009-12-10 | ISIS | Option Ex | 30,000 | 6.81 | 204,390 |
| 2009-12-14 | ISIS | Sale | 20,000 | 9.86 | 197,200 |
| 2009-12-14 | ISIS | Option Ex | 20,000 | 6.81 | 136,260 |
| 2009-12-11 | ISIS | Sale | 20,000 | 9.98 | 199,600 |
| 2009-12-10 | ISIS | Sale | 30,000 | 10.15 | 304,500 |
| 2009-12-09 | ISIS | Sale | 20,000 | 10.26 | 205,200 |
| 2009-12-08 | ISIS | Option Ex | 30,000 | 6.81 | 204,360 |
| 2009-12-09 | ISIS | Option Ex | 20,000 | 6.81 | 136,240 |
| 2009-12-08 | ISIS | Sale | 30,000 | 10.53 | 315,900 |
| 2009-12-07 | ISIS | Sale | 30,000 | 10.52 | 315,600 |
| 2009-12-07 | ISIS | Option Ex | 30,000 | 6.81 | 204,360 |
| 2009-12-04 | ISIS | Sale | 30,000 | 10.55 | 316,500 |
| 2009-12-04 | ISIS | Option Ex | 30,000 | 6.81 | 204,360 |
| 2008-12-30 | ISIS | Option Ex | 7,500 | 12.94 | 97,027 |
| 2008-12-30 | ISIS | Sale | 7,500 | 13.37 | 100,267 |
| 2008-12-26 | ISIS | Sale | 7,500 | 13.25 | 99,375 |
| 2008-12-26 | ISIS | Option Ex | 7,500 | 12.94 | 97,027 |
| 2008-12-23 | ISIS | Sale | 9,800 | 13.52 | 132,486 |
| 2008-12-23 | ISIS | Option Ex | 9,800 | 12.94 | 126,782 |
| 2008-12-19 | ISIS | Sale | 13,000 | 13.93 | 181,038 |
| 2008-12-19 | ISIS | Option Ex | 13,000 | 12.94 | 168,181 |
| 2008-12-17 | ISIS | Option Ex | 12,173 | 5.15 | 62,690 |
| 2008-12-17 | ISIS | Sale | 12,173 | 12.80 | 155,850 |
| 2007-12-26 | ISIS | Option Ex | 24,000 | 12.31 | 295,488 |
| 2007-12-28 | ISIS | Option Ex | 20,000 | 12.31 | 246,240 |
| 2007-12-26 | ISIS | Sale | 24,000 | 16.52 | 396,599 |
| 2007-12-27 | ISIS | Option Ex | 8,100 | 12.31 | 99,727 |
| 2007-12-28 | ISIS | Sale | 20,000 | 16.22 | 324,420 |
| 2007-12-27 | ISIS | Sale | 6,000 | 16.32 | 97,926 |
| 2007-12-11 | ISIS | Option Ex | 20,000 | 12.31 | 246,240 |
| 2007-12-11 | ISIS | Sale | 20,000 | 17.37 | 347,480 |
| 2007-11-30 | ISIS | Sale | 29,851 | 18.03 | 538,153 |
| 2007-11-28 | ISIS | Sale | 30,000 | 18.01 | 540,330 |
| 2007-11-30 | ISIS | Option Ex | 29,851 | 5.15 | 153,732 |
| 2007-11-28 | ISIS | Option Ex | 30,000 | 5.15 | 154,500 |
| 2006-11-13 | ISIS | Sale | 20,000 | 13.36 | 267,200 |
| 2006-11-09 | ISIS | Sale | 20,000 | 10.13 | 202,600 |
| 2006-11-10 | ISIS | Sale | 10,000 | 10.40 | 104,050 |
| Trade Date | Symbol | Trade Type | Shares | Price ($) | Value ($) |
|---|---|---|---|---|---|
| 2012-10-10 | RGLS | Buy | 750,000 | 4.00 | 3,000,000 |
Insider trading activities including stock purchases, stock sales, and option exercises listed in the above table cannot be completely guaranteed as to their accuracy. For more information regarding the trades made by Crooke Stanley T (Exec Chairman of the Board of Ionis Pharmaceuticals Inc at the time of this reporting) see the Securities and Exchange Commission (SEC) website.