Insider Trading activities at Acucela Inc. (M??????)

Insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Acucela Inc. (M??????) since 2014 are shown in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Acucela Inc.. Table 2 shows the detailed insider transactions. This company's CIK number is 1400482.

Total stock buying since 2014: $362,446,160,047.
Total stock sales since 2014: $3,277,960.
Total stock option exercises since 2014: $1,049,312.

8 insiders reported insider trading activities at Acucela Inc. (M??????):
▪ Insider trading activities of Gebhart John E
▪ Insider trading activities of Lowrance David L
▪ Insider trading activities of Sbi Holdings, Inc.
▪ Insider trading activities of Deyoung Hien
▪ Insider trading activities of Kubota Ryo
▪ Insider trading activities of Sbi Investment Co., Ltd.
▪ Insider trading activities of Danse Edward H
▪ Insider trading activities of Scheibler Lukas

Table 1. Yearly summary of insider stock purchases, sales, and option exercises at *Acucela Inc.* (*M??????*).
	Insider Buying		Insider Sales		Option Exercises
Year	Shares	Value	Shares	Value	Shares	Value
2017	37,300	$4,484,934,001	42,855	$316,547	70,954	$0
2016	6,696,900	$357,961,226,046	213,356	$2,227,736	259,699	$411,553
2015	0	$0	0	$0	10,000	$14,500
2014	0	$0	97,300	$733,677	154,100	$623,259

Table 2. Monthly summary of insider trading at *Acucela Inc.* (*M??????*).
Trading Period	Insider Buying		Insider Sales		Option Exercises
year-month	Shares	Value	Shares	Value	Shares	Value
2017-07	0	$0	6,125	$41,031	10,136	$0
2017-06	0	$0	5,760	$41,949	10,137	$0
2017-05	0	$0	5,990	$36,838	10,136	$0
2017-04	0	$0	5,820	$38,928	10,136	$0
2017-03	0	$0	6,050	$45,860	10,136	$0
2017-02	0	$0	6,575	$55,695	10,137	$0
2017-01	37,300	$4,484,934,001	6,535	$56,246	10,136	$0
2016-12	224,400	$357,864,283,936	5,180	$42,992	10,136	$0
2016-11	0	$0	4,437	$41,635	10,136	$0
2016-10	0	$0	0	$0	10,137	$0
2016-09	0	$0	71,663	$734,629	10,136	$0
2016-08	0	$0	132,076	$1,408,480	114,535	$411,553
2016-07	0	$0	0	$0	7,473	$0
2016-06	6,472,500	$96,942,110	0	$0	7,473	$0
2016-05	0	$0	0	$0	89,673	$0
2015-12	0	$0	0	$0	10,000	$14,500
2014-08	0	$0	97,300	$733,677	154,100	$623,259

Table 3. Detailed insider trading at *Acucela Inc.* (*M??????*)
Trade Date	Insider Name	Trade Type	Shares	Price ($)	Value ($)
2017-07-17	Scheibler Lukas (EVP of Research & Development)	Sale	1,250	6.50	8,125
2017-07-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,663	.00	0
2017-07-05	Gebhart John E (Chief Financial Officer)	Sale	3,700	6.75	24,975
2017-07-05	Danse Edward H (Chief Business Officer)	Sale	1,175	6.75	7,931
2017-07-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2017-06-20	Scheibler Lukas (EVP of Research & Development)	Sale	1,300	6.95	9,035
2017-06-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,664	.00	0
2017-06-01	Gebhart John E (Chief Financial Officer)	Sale	3,380	7.38	24,944
2017-06-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2017-06-01	Danse Edward H (Chief Business Officer)	Sale	1,080	7.38	7,970
2017-05-17	Scheibler Lukas (EVP of Research & Development)	Sale	1,275	6.15	7,841
2017-05-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,663	.00	0
2017-05-01	Gebhart John E (Chief Financial Officer)	Sale	3,615	6.15	22,232
2017-05-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2017-05-01	Danse Edward H (Chief Business Officer)	Sale	1,100	6.15	6,765
2017-04-17	Scheibler Lukas (EVP of Research & Development)	Sale	1,320	6.48	8,553
2017-04-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,664	.00	0
2017-04-04	Gebhart John E (Chief Financial Officer)	Sale	3,400	6.75	22,950
2017-04-04	Danse Edward H (Chief Business Officer)	Sale	1,100	6.75	7,425
2017-04-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,472	.00	0
2017-03-20	Scheibler Lukas (EVP of Research & Development)	Sale	1,250	7.10	8,875
2017-03-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,663	.00	0
2017-03-02	Gebhart John E (Chief Financial Officer)	Sale	3,550	7.70	27,335
2017-03-02	Danse Edward H (Chief Business Officer)	Sale	1,250	7.72	9,650
2017-03-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2017-02-17	Scheibler Lukas (EVP of Research & Development)	Sale	1,450	8.10	11,745
2017-02-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,664	.00	0
2017-02-02	Gebhart John E (Chief Financial Officer)	Sale	3,875	8.60	33,325
2017-02-02	Danse Edward H (Chief Business Officer)	Sale	1,250	8.50	10,625
2017-02-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2017-01-23	Sbi Holdings, Inc. (10% Owner)	Buy	17,200	150,643.21	2,591,063,212
2017-01-20	Sbi Holdings, Inc. (10% Owner)	Buy	12,900	111,884.33	1,443,307,857
2017-01-19	Sbi Holdings, Inc. (10% Owner)	Buy	100	869.60	86,960
2017-01-18	Scheibler Lukas (EVP of Research & Development)	Sale	1,475	8.70	12,832
2017-01-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,663	.00	0
2017-01-12	Sbi Holdings, Inc. (10% Owner)	Buy	7,100	63,447.32	450,475,972
2017-01-04	Gebhart John E (Chief Financial Officer)	Sale	3,790	8.58	32,518
2017-01-04	Danse Edward H (Chief Business Officer)	Sale	1,270	8.58	10,896
2017-01-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2016-12-30	Sbi Holdings, Inc. (10% Owner)	Buy	2,700	22,970.05	62,019,135
2016-12-29	Sbi Holdings, Inc. (10% Owner)	Buy	16,900	143,507.13	2,425,270,497
2016-12-28	Sbi Holdings, Inc. (10% Owner)	Buy	204,800	1,735,239.23	355,376,994,304
2016-12-22	Scheibler Lukas (EVP of Research & Development)	Sale	880	8.18	7,198
2016-12-22	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,664	.00	0
2016-12-22	Gebhart John E (Chief Financial Officer)	Sale	3,210	8.18	26,257
2016-12-22	Gebhart John E (Chief Financial Officer)	Option Ex	7,472	.00	0
2016-12-15	Danse Edward H (Chief Business Officer)	Sale	1,090	8.75	9,537
2016-11-21	Scheibler Lukas (EVP of Research & Development)	Sale	2,663	9.35	24,891
2016-11-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,663	.00	0
2016-11-14	Scheibler Lukas (EVP of Research & Development)	Sale	1,774	9.44	16,744
2016-11-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2016-10-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,664	.00	0
2016-10-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2016-09-29	Gebhart John E (Chief Financial Officer)	Sale	9,000	13.09	117,828
2016-09-20	Scheibler Lukas (EVP of Research & Development)	Sale	2,663	9.53	25,381
2016-09-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	2,663	.00	0
2016-09-12	Gebhart John E (Chief Financial Officer)	Sale	60,000	9.86	591,420
2016-09-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2016-08-31	Danse Edward H (Chief Business Officer)	Sale	25,013	10.04	251,130
2016-08-18	Scheibler Lukas (EVP of Research & Development)	Sale	31,962	10.81	345,509
2016-08-18	Danse Edward H (Chief Business Officer)	Sale	75,101	10.81	811,841
2016-08-18	Danse Edward H (Chief Business Officer)	Option Ex	75,101	5.48	411,553
2016-08-17	Scheibler Lukas (EVP of Research & Development)	Option Ex	31,962	.00	0
2016-08-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,472	.00	0
2016-07-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2016-06-27	Sbi Investment Co., Ltd. (10% Owner)	Buy	617,800	22.15	13,684,270
2016-06-24	Sbi Investment Co., Ltd. (10% Owner)	Buy	478,600	17.67	8,456,862
2016-06-23	Sbi Investment Co., Ltd. (10% Owner)	Buy	991,000	19.05	18,878,550
2016-06-22	Sbi Investment Co., Ltd. (10% Owner)	Buy	456,400	16.21	7,398,244
2016-06-21	Sbi Investment Co., Ltd. (10% Owner)	Buy	555,000	16.13	8,952,150
2016-06-20	Sbi Investment Co., Ltd. (10% Owner)	Buy	723,200	16.03	11,592,896
2016-06-17	Sbi Investment Co., Ltd. (10% Owner)	Buy	776,300	12.53	9,727,039
2016-06-16	Sbi Investment Co., Ltd. (10% Owner)	Buy	257,000	11.13	2,860,410
2016-06-15	Sbi Investment Co., Ltd. (10% Owner)	Buy	1,018,400	9.30	9,471,120
2016-06-03	Sbi Investment Co., Ltd. (10% Owner)	Buy	256,300	9.63	2,468,169
2016-06-02	Sbi Investment Co., Ltd. (10% Owner)	Buy	342,500	10.08	3,452,400
2016-06-01	Gebhart John E (Chief Financial Officer)	Option Ex	7,473	.00	0
2016-05-01	Gebhart John E (Chief Financial Officer)	Option Ex	89,673	.00	0
2015-12-15	Kubota Ryo (CEO, President and COB)	Option Ex	10,000	1.45	14,500
2014-08-26	Deyoung Hien (VP Human Resources)	Sale	56,800	7.89	448,152
2014-08-26	Deyoung Hien (VP Human Resources)	Option Ex	56,800	3.88	220,100
2014-08-20	Deyoung Hien (VP Human Resources)	Option Ex	56,800	3.88	220,100
2014-08-18	Lowrance David L (CFO, Secretary, Treasurer)	Sale	40,500	7.05	285,525
2014-08-18	Lowrance David L (CFO, Secretary, Treasurer)	Option Ex	40,500	4.52	183,059

Insider trading activities including stock purchases, stock sales, and option exercises of M?????? listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Acucela Inc. (symbol M??????, CIK number 1400482) see the Securities and Exchange Commission (SEC) website.

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