Insider Trading activities of Opko Health, Inc. insiders. , Part 4

Monthly summaries of insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Opko Health, Inc. since 2005 are illustrated in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Opko Health, Inc. since year 2005. (See page 1 of this report.) Table 2 shows the detailed insider transactions of Opko Health, Inc. since 2005. The reporting company's ticker symbol is OPK. The reporting company's CIK number is 944809.
The total value of stock buying since 2005 is $371,450,121.
The total value of stock sales since 2005 is $4,562,093.
The total value of stock option exercises since 2005 is $44,690,792.



Table 2. Detailed insider stock purchases, sales, and option exercises of Opko Health, Inc. insiders (OPK) , Part 4
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2015-03-31 Frost Gamma Investments Trust (10% Owner) Buy 23,400 14.32 335,088
2015-03-25 Frost Gamma Investments Trust (10% Owner) Buy 32,400 14.15 458,362
2015-03-20 Frost Gamma Investments Trust (10% Owner) Buy 14,400 14.49 208,598
2015-03-13 Logal Adam (Sr. Vice President, CFO) Sale 41,488 14.61 606,305
2015-03-12 Logal Adam (Sr. Vice President, CFO) Option Ex 95,000 1.41 133,475
2015-03-10 Frost Gamma Investments Trust (10% Owner) Buy 5,400 13.83 74,660
2015-03-09 Frost Gamma Investments Trust (10% Owner) Buy 10,800 13.99 151,102
2015-03-06 Frost Gamma Investments Trust (10% Owner) Buy 12,600 14.18 178,630
2015-03-05 Frost Gamma Investments Trust (10% Owner) Buy 5,400 14.34 77,452
2015-03-04 Frost Gamma Investments Trust (10% Owner) Buy 10,800 14.34 154,861
2015-03-03 Frost Gamma Investments Trust (10% Owner) Buy 18,200 14.14 257,293
2015-03-02 Frost Gamma Investments Trust (10% Owner) Buy 44,800 14.01 627,827
2015-02-13 Frost Gamma Investments Trust (10% Owner) Buy 25,000 13.61 340,300
2015-02-03 Frost Gamma Investments Trust (10% Owner) Buy 25,000 12.11 302,750
2015-01-31 Rubin Steven D (Executive VP-Administration) Option Ex 5,832,598 .67 3,902,008
2015-01-31 Frost Gamma Investments Trust (10% Owner) Option Ex 14,786,430 .66 9,744,257
2015-01-31 Hsiao Jane Ph D (Vice Chairman & CTO) Option Ex 7,732,738 .67 5,173,201
2015-01-28 Frost Gamma Investments Trust (10% Owner) Buy 15,000 11.27 169,020
2015-01-23 Frost Gamma Investments Trust (10% Owner) Buy 10,000 10.84 108,379
2015-01-22 Frost Gamma Investments Trust (10% Owner) Buy 28,000 10.47 293,216
2015-01-21 Frost Gamma Investments Trust (10% Owner) Buy 41,700 10.23 426,591
2015-01-20 Frost Gamma Investments Trust (10% Owner) Buy 45,000 10.13 456,075
2015-01-16 Frost Gamma Investments Trust (10% Owner) Buy 25,000 10.01 250,225
2015-01-15 Frost Gamma Investments Trust (10% Owner) Buy 44,000 10.06 442,595
2015-01-13 Frost Gamma Investments Trust (10% Owner) Buy 25,000 10.13 253,275
2015-01-09 Frost Gamma Investments Trust (10% Owner) Buy 9,200 10.10 92,910
2015-01-08 Frost Gamma Investments Trust (10% Owner) Buy 22,300 10.03 223,691
2015-01-06 Frost Gamma Investments Trust (10% Owner) Buy 26,000 9.91 257,738
2015-01-02 Frost Gamma Investments Trust (10% Owner) Buy 28,000 9.91 277,620
2014-12-31 Frost Gamma Investments Trust (10% Owner) Buy 92,500 10.00 924,630
2014-12-23 Frost Gamma Investments Trust (10% Owner) Buy 40,000 9.45 377,879
2014-12-22 Frost Gamma Investments Trust (10% Owner) Buy 10,000 9.79 97,950
2014-12-17 Frost Gamma Investments Trust (10% Owner) Buy 15,000 9.15 137,310
2014-11-21 Frost Gamma Investments Trust (10% Owner) Buy 40,000 8.14 325,800
2014-11-20 Frost Gamma Investments Trust (10% Owner) Buy 62,500 8.11 506,937
2014-11-19 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.17 204,175
2014-11-17 Frost Gamma Investments Trust (10% Owner) Buy 22,000 8.24 181,214
2014-11-14 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.27 165,320
2014-11-14 Beier Thomas E (Director) Option Ex 10,227 2.78 28,431
2014-11-13 Frost Gamma Investments Trust (10% Owner) Buy 12,400 8.35 103,490
2014-11-12 Frost Gamma Investments Trust (10% Owner) Buy 67,800 8.38 568,503
2014-11-12 Frost Gamma Investments Trust (10% Owner) Option Ex 210,821 .00 421
2014-11-07 Frost Gamma Investments Trust (10% Owner) Buy 90,000 8.28 745,380
2014-11-06 Frost Gamma Investments Trust (10% Owner) Buy 28,600 8.37 239,410
2014-11-05 Frost Gamma Investments Trust (10% Owner) Buy 33,200 8.36 277,552
2014-11-04 Frost Gamma Investments Trust (10% Owner) Buy 33,600 8.35 280,459
2014-11-03 Frost Gamma Investments Trust (10% Owner) Buy 23,600 8.35 197,154
2014-10-31 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.39 167,760
2014-10-30 Frost Gamma Investments Trust (10% Owner) Buy 32,500 8.33 270,595
2014-10-29 Frost Gamma Investments Trust (10% Owner) Buy 35,000 8.38 293,300
2014-10-24 Frost Gamma Investments Trust (10% Owner) Buy 40,000 8.40 336,040
2014-10-22 Frost Gamma Investments Trust (10% Owner) Buy 64,800 8.23 533,044
2014-10-17 Frost Gamma Investments Trust (10% Owner) Buy 30,000 8.25 247,500
2014-10-16 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.33 166,540
2014-10-13 Frost Gamma Investments Trust (10% Owner) Buy 54,000 8.21 443,178
2014-10-10 Frost Gamma Investments Trust (10% Owner) Buy 82,300 8.19 674,119
2014-10-09 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.41 210,325
2014-10-08 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.36 167,120
2014-10-07 Frost Gamma Investments Trust (10% Owner) Buy 55,000 8.30 456,390
2014-10-06 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.37 83,650
2014-10-03 Frost Gamma Investments Trust (10% Owner) Buy 29,400 8.43 247,842
2014-10-02 Frost Gamma Investments Trust (10% Owner) Buy 35,000 8.30 290,605
2014-10-01 Frost Gamma Investments Trust (10% Owner) Buy 40,000 8.41 336,240
2014-09-30 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.57 214,250
2014-09-26 Frost Gamma Investments Trust (10% Owner) Buy 24,000 8.57 205,704
2014-09-25 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.52 85,150
2014-09-24 Frost Gamma Investments Trust (10% Owner) Buy 63,000 8.23 518,301
2014-09-24 Hsiao Jane Ph D (Vice Chairman & CTO) Option Ex 201,613 2.48 500,000
2014-09-23 Frost Gamma Investments Trust (10% Owner) Buy 70,100 8.33 584,213
2014-09-19 Frost Gamma Investments Trust (10% Owner) Buy 35,000 8.42 294,700
2014-09-18 Frost Gamma Investments Trust (10% Owner) Buy 40,000 8.49 339,560
2014-09-16 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.49 212,150
2014-09-15 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.52 170,340
2014-09-12 Frost Gamma Investments Trust (10% Owner) Buy 15,000 8.57 128,595
2014-09-11 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.54 170,900
2014-09-10 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.55 85,540
2014-09-09 Frost Gamma Investments Trust (10% Owner) Buy 35,700 8.54 304,877
2014-09-05 Frost Gamma Investments Trust (10% Owner) Buy 58,000 8.48 491,724
2014-09-04 Frost Gamma Investments Trust (10% Owner) Buy 35,000 8.62 301,630
2014-09-02 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.78 87,820
2014-08-29 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.91 178,220
2014-08-28 Frost Gamma Investments Trust (10% Owner) Buy 30,000 8.84 265,110
2014-08-27 Frost Gamma Investments Trust (10% Owner) Buy 35,000 8.88 310,800
2014-08-22 Frost Gamma Investments Trust (10% Owner) Buy 31,000 8.79 272,583
2014-08-21 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.81 220,299
2014-08-20 Frost Gamma Investments Trust (10% Owner) Buy 35,000 8.91 311,710
2014-08-19 Frost Gamma Investments Trust (10% Owner) Buy 10,000 9.06 90,580
2014-08-15 Frost Gamma Investments Trust (10% Owner) Buy 11,400 9.08 103,557
2014-08-14 Frost Gamma Investments Trust (10% Owner) Buy 19,300 9.04 174,452
2014-08-12 Frost Gamma Investments Trust (10% Owner) Buy 63,000 8.96 564,417
2014-08-04 Frost Gamma Investments Trust (10% Owner) Buy 5,000 8.75 43,750
2014-08-01 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.66 216,500
2014-08-01 Hsiao Jane Ph D (Vice Chairman & CTO) Option Ex 309,583 4.18 1,294,056
2014-07-30 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.97 224,350
2014-07-29 Frost Gamma Investments Trust (10% Owner) Buy 18,500 9.06 167,610
2014-07-28 Frost Gamma Investments Trust (10% Owner) Option Ex 654,925 1.57 1,028,232
2014-07-25 Frost Gamma Investments Trust (10% Owner) Buy 36,000 9.03 325,008
2014-07-23 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.90 88,980
2014-07-22 Frost Gamma Investments Trust (10% Owner) Buy 30,000 8.67 259,980
2014-07-17 Frost Gamma Investments Trust (10% Owner) Buy 40,000 8.63 345,280
2014-07-16 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.76 175,180
2014-07-15 Frost Gamma Investments Trust (10% Owner) Buy 26,000 8.72 226,798
2014-07-14 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.91 178,180
2014-07-10 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.82 176,340
2014-07-08 Frost Gamma Investments Trust (10% Owner) Buy 30,000 8.60 257,850
2014-07-07 Frost Gamma Investments Trust (10% Owner) Buy 27,000 8.79 237,357
2014-07-03 Frost Gamma Investments Trust (10% Owner) Buy 45,800 8.90 407,436
2014-07-02 Frost Gamma Investments Trust (10% Owner) Buy 13,000 8.78 114,127
2014-07-01 Frost Gamma Investments Trust (10% Owner) Buy 15,000 8.90 133,545
2014-06-30 Frost Gamma Investments Trust (10% Owner) Buy 15,000 8.95 134,295
2014-06-27 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.97 179,440
2014-06-25 Frost Gamma Investments Trust (10% Owner) Buy 65,000 8.66 562,835
2014-06-24 Frost Gamma Investments Trust (10% Owner) Buy 40,000 8.84 353,640
2014-06-23 Frost Gamma Investments Trust (10% Owner) Buy 15,000 9.05 135,795
2014-06-20 Frost Gamma Investments Trust (10% Owner) Buy 45,000 9.18 412,965
2014-06-19 Frost Gamma Investments Trust (10% Owner) Buy 50,000 9.24 462,000
2014-06-18 Frost Gamma Investments Trust (10% Owner) Buy 20,000 9.35 186,980
2014-06-12 Frost Gamma Investments Trust (10% Owner) Buy 50,000 9.00 449,899
2014-06-11 Frost Gamma Investments Trust (10% Owner) Buy 50,000 9.10 454,800
2014-06-10 Frost Gamma Investments Trust (10% Owner) Buy 20,500 9.16 187,882
2014-06-06 Frost Gamma Investments Trust (10% Owner) Buy 10,000 9.30 93,000
2014-06-05 Yu Alice Lin-tsing (Director) Option Ex 20,000 1.23 24,600
2014-06-04 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.78 175,580
2014-05-30 Frost Gamma Investments Trust (10% Owner) Buy 36,000 8.60 309,492
2014-05-21 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.30 82,990
2014-05-20 Frost Gamma Investments Trust (10% Owner) Buy 26,600 8.27 220,088
2014-05-15 Frost Gamma Investments Trust (10% Owner) Buy 24,400 8.09 197,444
2014-05-14 Frost Gamma Investments Trust (10% Owner) Buy 25,500 8.20 209,176
2014-05-13 Frost Gamma Investments Trust (10% Owner) Buy 20,400 8.37 170,686
2014-05-12 Frost Gamma Investments Trust (10% Owner) Buy 10,000 8.46 84,600
2014-05-09 Frost Gamma Investments Trust (10% Owner) Buy 100,000 8.17 817,000
2014-05-08 Frost Gamma Investments Trust (10% Owner) Buy 73,900 8.09 598,072
2014-05-07 Frost Gamma Investments Trust (10% Owner) Buy 37,500 8.16 306,112
2014-05-06 Frost Gamma Investments Trust (10% Owner) Buy 33,900 8.28 280,522
2014-05-05 Frost Gamma Investments Trust (10% Owner) Buy 16,500 8.35 137,709
2014-05-02 Frost Gamma Investments Trust (10% Owner) Buy 26,000 8.27 214,890
2014-05-01 Frost Gamma Investments Trust (10% Owner) Buy 20,000 8.34 166,759
2014-04-30 Frost Gamma Investments Trust (10% Owner) Buy 25,000 8.18 204,400
2014-04-25 Frost Gamma Investments Trust (10% Owner) Buy 36,200 8.04 291,156
2014-04-24 Frost Gamma Investments Trust (10% Owner) Buy 12,400 8.26 102,424
2014-04-23 Frost Gamma Investments Trust (10% Owner) Buy 36,300 8.17 296,643
2014-04-22 Frost Gamma Investments Trust (10% Owner) Buy 89,500 8.29 741,954
2014-04-21 Frost Gamma Investments Trust (10% Owner) Buy 100,000 8.32 832,199
2014-04-17 Frost Gamma Investments Trust (10% Owner) Buy 51,000 8.13 414,885
2014-04-15 Rubin Steven D (Executive VP-Administration) Sale 79,300 8.10 642,647
2014-04-15 Frost Gamma Investments Trust (10% Owner) Buy 129,800 8.04 1,043,591
2014-04-15 Lerner Richard A (Director) Option Ex 40,000 1.66 66,400
2014-04-15 Hsiao Jane Ph D (Vice Chairman & CTO) Buy 10,000 8.03 80,300
2014-04-14 Rubin Steven D (Executive VP-Administration) Sale 100,000 8.58 857,700
2014-04-14 Frost Gamma Investments Trust (10% Owner) Buy 110,600 8.46 935,676

Insider trading activities including stock purchases, stock sales, and option exercises of OPK listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Opko Health, Inc. (symbol OPK, CIK number 944809) see the Securities and Exchange Commission (SEC) website.