Insider Trading activities of Opko Health, Inc. insiders. , Part 6

Monthly summaries of insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Opko Health, Inc. since 2005 are illustrated in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Opko Health, Inc. since year 2005. (See page 1 of this report.) Table 2 shows the detailed insider transactions of Opko Health, Inc. since 2005. The reporting company's ticker symbol is OPK. The reporting company's CIK number is 944809.
The total value of stock buying since 2005 is $373,446,519.
The total value of stock sales since 2005 is $4,562,093.
The total value of stock option exercises since 2005 is $44,690,792.



Table 2. Detailed insider stock purchases, sales, and option exercises of Opko Health, Inc. insiders (OPK) , Part 6
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2013-05-15 Frost Gamma Investments Trust (10% Owner) Buy 13,300 7.11 94,576
2013-05-14 Frost Gamma Investments Trust (10% Owner) Buy 35,100 6.93 243,102
2013-05-13 Frost Gamma Investments Trust (10% Owner) Buy 46,900 6.84 321,030
2013-05-10 Frost Gamma Investments Trust (10% Owner) Buy 10,500 6.87 72,145
2013-05-09 Frost Gamma Investments Trust (10% Owner) Buy 10,700 6.78 72,513
2013-05-08 Frost Gamma Investments Trust (10% Owner) Buy 42,000 6.70 281,274
2013-05-07 Frost Gamma Investments Trust (10% Owner) Buy 22,500 6.76 152,010
2013-05-06 Frost Gamma Investments Trust (10% Owner) Buy 23,800 6.69 159,198
2013-05-03 Frost Gamma Investments Trust (10% Owner) Buy 27,500 6.69 184,002
2013-05-02 Frost Gamma Investments Trust (10% Owner) Buy 80,000 6.57 525,760
2013-05-01 Rubin Steven D (Executive VP-Administration) Buy 4,300 6.46 27,778
2013-05-01 Frost Gamma Investments Trust (10% Owner) Buy 72,500 6.44 467,045
2013-04-30 Frost Gamma Investments Trust (10% Owner) Buy 45,000 6.71 301,995
2013-04-29 Frost Gamma Investments Trust (10% Owner) Buy 25,000 6.86 171,575
2013-04-26 Frost Gamma Investments Trust (10% Owner) Buy 50,000 6.92 346,000
2013-04-24 Frost Gamma Investments Trust (10% Owner) Buy 100,000 6.89 689,400
2013-04-10 Frost Gamma Investments Trust (10% Owner) Buy 20,000 7.09 141,800
2013-04-09 Frost Gamma Investments Trust (10% Owner) Buy 250,600 6.99 1,751,192
2013-04-05 Frost Gamma Investments Trust (10% Owner) Buy 28,000 7.18 200,956
2013-04-04 Frost Gamma Investments Trust (10% Owner) Buy 22,200 7.17 159,196
2013-04-03 Frost Gamma Investments Trust (10% Owner) Buy 156,500 6.99 1,093,152
2013-04-03 Hsiao Jane Ph D (Vice Chairman & CTO) Buy 5,000 6.99 34,950
2013-04-02 Frost Gamma Investments Trust (10% Owner) Buy 91,900 7.44 684,011
2013-04-01 Frost Gamma Investments Trust (10% Owner) Buy 66,900 7.46 499,007
2013-03-28 Frost Gamma Investments Trust (10% Owner) Buy 16,500 7.61 125,565
2013-03-27 Frost Gamma Investments Trust (10% Owner) Buy 22,900 7.59 173,742
2013-03-26 Frost Gamma Investments Trust (10% Owner) Buy 22,500 7.62 171,450
2013-03-25 Frost Gamma Investments Trust (10% Owner) Buy 31,600 7.55 238,611
2013-03-22 Frost Gamma Investments Trust (10% Owner) Buy 14,500 7.59 110,055
2013-03-21 Frost Gamma Investments Trust (10% Owner) Buy 68,500 7.40 506,694
2013-03-19 Frost Gamma Investments Trust (10% Owner) Buy 48,300 7.53 363,747
2013-03-18 Frost Gamma Investments Trust (10% Owner) Buy 42,800 7.63 326,735
2013-03-15 Lerner Richard A (Director) Buy 13,100 7.63 99,953
2013-03-14 Frost Gamma Investments Trust (10% Owner) Buy 32,700 7.53 246,361
2013-03-13 Frost Gamma Investments Trust (10% Owner) Buy 37,100 7.14 265,005
2013-03-12 Frost Gamma Investments Trust (10% Owner) Buy 23,500 7.47 175,592
2013-03-11 Frost Gamma Investments Trust (10% Owner) Buy 38,000 7.46 283,290
2013-03-08 Frost Gamma Investments Trust (10% Owner) Buy 43,000 7.35 316,222
2013-03-08 Frost Gamma Investments Trust (10% Owner) Option Ex 2,520,190 .00 0
2013-03-08 Hsiao Jane Ph D (Vice Chairman & CTO) Option Ex 806,450 .00 0
2013-03-07 Frost Gamma Investments Trust (10% Owner) Buy 51,500 7.35 378,525
2013-03-06 Frost Gamma Investments Trust (10% Owner) Buy 44,000 7.29 320,980
2013-03-05 Frost Gamma Investments Trust (10% Owner) Buy 52,000 7.28 378,456
2013-03-04 Frost Gamma Investments Trust (10% Owner) Buy 35,500 7.06 250,701
2013-03-01 Frost Gamma Investments Trust (10% Owner) Buy 20,000 7.00 140,080
2013-02-28 Frost Gamma Investments Trust (10% Owner) Buy 145,000 7.00 1,015,578
2013-02-27 Frost Gamma Investments Trust (10% Owner) Buy 55,000 7.08 389,455
2013-02-26 Frost Gamma Investments Trust (10% Owner) Buy 65,000 6.98 453,765
2013-02-25 Frost Gamma Investments Trust (10% Owner) Buy 35,000 7.12 249,095
2013-02-22 Frost Gamma Investments Trust (10% Owner) Buy 45,000 7.02 315,900
2013-02-21 Frost Gamma Investments Trust (10% Owner) Buy 10,000 6.67 66,740
2013-02-20 Frost Gamma Investments Trust (10% Owner) Buy 88,000 6.65 585,552
2013-02-19 Frost Gamma Investments Trust (10% Owner) Buy 25,000 6.75 168,675
2013-02-15 Frost Gamma Investments Trust (10% Owner) Buy 57,500 6.74 387,262
2013-02-14 Frost Gamma Investments Trust (10% Owner) Buy 40,000 6.84 273,440
2013-02-13 Frost Gamma Investments Trust (10% Owner) Buy 20,000 6.67 133,320
2013-02-12 Frost Gamma Investments Trust (10% Owner) Buy 45,000 6.72 302,265
2013-02-08 Frost Gamma Investments Trust (10% Owner) Buy 110,000 6.32 695,640
2013-02-07 Frost Gamma Investments Trust (10% Owner) Buy 37,500 6.88 257,887
2013-02-06 Frost Gamma Investments Trust (10% Owner) Buy 30,000 6.90 207,000
2013-02-01 Logal Adam (VP Finance, CAO & Treasurer) Sale 50,000 6.72 335,850
2013-02-01 Logal Adam (VP Finance, CAO & Treasurer) Option Ex 50,000 .56 28,000
2013-01-31 Frost Gamma Investments Trust (10% Owner) Buy 40,000 6.46 258,400
2013-01-15 Frost Gamma Investments Trust (10% Owner) Buy 35,000 5.70 199,395
2013-01-14 Frost Gamma Investments Trust (10% Owner) Buy 20,000 5.60 112,080
2013-01-11 Frost Gamma Investments Trust (10% Owner) Buy 30,000 5.35 160,590
2013-01-10 Frost Gamma Investments Trust (10% Owner) Buy 46,000 5.29 243,110
2013-01-09 Frost Gamma Investments Trust (10% Owner) Buy 50,000 5.20 260,049
2013-01-04 Frost Gamma Investments Trust (10% Owner) Buy 40,000 5.17 206,600
2013-01-03 Frost Gamma Investments Trust (10% Owner) Buy 25,000 5.03 125,750
2013-01-02 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.98 149,310
2012-12-31 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.71 471,500
2012-12-28 Frost Gamma Investments Trust (10% Owner) Buy 55,000 4.75 261,415
2012-12-27 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.70 117,524
2012-12-26 Frost Gamma Investments Trust (10% Owner) Buy 85,000 4.68 397,970
2012-12-24 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.63 138,960
2012-12-21 Frost Gamma Investments Trust (10% Owner) Buy 80,000 4.66 372,879
2012-12-20 Frost Gamma Investments Trust (10% Owner) Buy 62,500 4.73 295,625
2012-12-19 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.77 95,340
2012-12-18 Frost Gamma Investments Trust (10% Owner) Buy 35,000 4.67 163,555
2012-12-17 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.61 184,360
2012-12-14 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.58 183,280
2012-12-14 Pfenniger Richard C Jr (Director) Option Ex 100,000 2.04 203,700
2012-12-13 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.54 136,200
2012-12-12 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.54 136,110
2012-12-11 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.50 179,800
2012-12-10 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.39 131,850
2012-12-07 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.36 326,850
2012-12-06 Frost Gamma Investments Trust (10% Owner) Buy 35,000 4.36 152,635
2012-12-05 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.38 131,430
2012-12-04 Frost Gamma Investments Trust (10% Owner) Buy 32,500 4.38 142,415
2012-12-03 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.40 109,925
2012-11-30 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.45 88,900
2012-11-29 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.46 133,650
2012-11-28 Frost Gamma Investments Trust (10% Owner) Buy 85,000 4.41 374,510
2012-11-27 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.43 44,320
2012-11-26 Frost Gamma Investments Trust (10% Owner) Buy 65,000 4.43 287,950
2012-11-23 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.46 111,525
2012-11-21 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.43 199,395
2012-11-20 Frost Gamma Investments Trust (10% Owner) Buy 7,500 4.46 33,412
2012-11-19 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.41 44,100
2012-11-16 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.39 109,749
2012-11-15 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.43 110,674
2012-11-14 Frost Gamma Investments Trust (10% Owner) Buy 62,500 4.42 276,375
2012-11-13 Frost Gamma Investments Trust (10% Owner) Buy 15,000 4.49 67,365
2012-11-12 Frost Gamma Investments Trust (10% Owner) Buy 77,500 4.43 343,325
2012-11-09 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.52 113,025
2012-11-08 Frost Gamma Investments Trust (10% Owner) Buy 35,000 4.57 159,810
2012-11-07 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.33 216,750
2012-11-06 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.24 317,700
2012-11-05 Frost Gamma Investments Trust (10% Owner) Buy 65,000 4.25 276,250
2012-11-02 Frost Gamma Investments Trust (10% Owner) Buy 80,000 4.26 340,880
2012-11-01 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.30 322,200
2012-10-31 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.28 320,775
2012-10-26 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.34 325,575
2012-10-25 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.43 110,750
2012-10-24 Frost Gamma Investments Trust (10% Owner) Buy 42,500 4.50 191,292
2012-10-23 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.46 111,625
2012-10-22 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.45 111,300
2012-10-19 Frost Gamma Investments Trust (10% Owner) Buy 190,000 4.53 859,750
2012-10-11 Frost Gamma Investments Trust (10% Owner) Buy 105,000 4.30 452,024
2012-10-10 Frost Gamma Investments Trust (10% Owner) Buy 55,000 4.30 236,280
2012-10-09 Frost Gamma Investments Trust (10% Owner) Buy 95,900 4.34 416,014
2012-10-09 Hsiao Jane Ph D (Vice Chairman & CTO) Buy 10,000 4.33 43,320
2012-10-08 Frost Gamma Investments Trust (10% Owner) Buy 137,500 4.43 609,125
2012-10-05 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.50 269,820
2012-10-04 Frost Gamma Investments Trust (10% Owner) Buy 77,500 4.41 341,465
2012-10-03 Frost Gamma Investments Trust (10% Owner) Buy 65,000 4.34 282,425
2012-10-02 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.18 418,300
2012-10-01 Frost Gamma Investments Trust (10% Owner) Buy 212,500 4.16 883,149
2012-09-28 Frost Gamma Investments Trust (10% Owner) Buy 47,500 4.20 199,310
2012-09-27 Frost Gamma Investments Trust (10% Owner) Buy 62,500 4.17 260,749
2012-09-26 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.13 309,600
2012-09-25 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.16 166,360
2012-09-24 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.16 187,065
2012-09-21 Frost Gamma Investments Trust (10% Owner) Buy 150,000 4.23 634,050
2012-09-20 Frost Gamma Investments Trust (10% Owner) Buy 110,000 4.31 473,880
2012-09-19 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.41 198,450
2012-09-18 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.43 110,750
2012-09-17 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.41 176,280
2012-09-14 Frost Gamma Investments Trust (10% Owner) Buy 55,000 4.47 245,740
2012-09-13 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.43 132,930
2012-09-12 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.38 131,250
2012-09-11 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.38 262,620
2012-09-10 Frost Gamma Investments Trust (10% Owner) Buy 90,000 4.40 395,640
2012-09-07 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.47 223,550
2012-08-31 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.47 89,320
2012-08-30 Frost Gamma Investments Trust (10% Owner) Buy 22,500 4.45 100,035
2012-08-29 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.48 89,540
2012-08-28 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.46 200,745

Insider trading activities including stock purchases, stock sales, and option exercises of OPK listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Opko Health, Inc. (symbol OPK, CIK number 944809) see the Securities and Exchange Commission (SEC) website.