Insider Trading activities of Opko Health, Inc. insiders. , Part 7

Monthly summaries of insider trading activities (stock purchases, sales, and option exercises) reported by insiders of Opko Health, Inc. since 2005 are illustrated in Table 1 and Table 2. Table 1 shows the monthly insider trading data of Opko Health, Inc. since year 2005. (See page 1 of this report.) Table 2 shows the detailed insider transactions of Opko Health, Inc. since 2005. The reporting company's ticker symbol is OPK. The reporting company's CIK number is 944809.
The total value of stock buying since 2005 is $373,805,983.
The total value of stock sales since 2005 is $4,562,093.
The total value of stock option exercises since 2005 is $44,690,792.



Table 2. Detailed insider stock purchases, sales, and option exercises of Opko Health, Inc. insiders (OPK) , Part 7
  Trade Date   Insider Name Trade Type     Shares       Price ($)   Value ($)
2012-09-11 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.38 262,620
2012-09-10 Frost Gamma Investments Trust (10% Owner) Buy 90,000 4.40 395,640
2012-09-07 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.47 223,550
2012-08-31 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.47 89,320
2012-08-30 Frost Gamma Investments Trust (10% Owner) Buy 22,500 4.45 100,035
2012-08-29 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.48 89,540
2012-08-28 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.46 200,745
2012-08-27 Frost Gamma Investments Trust (10% Owner) Buy 42,500 4.49 190,740
2012-08-24 Frost Gamma Investments Trust (10% Owner) Buy 47,500 4.49 213,037
2012-08-23 Frost Gamma Investments Trust (10% Owner) Buy 32,500 4.44 144,300
2012-08-22 Frost Gamma Investments Trust (10% Owner) Buy 35,000 4.38 153,440
2012-08-21 Frost Gamma Investments Trust (10% Owner) Buy 80,000 4.33 346,079
2012-08-20 Frost Gamma Investments Trust (10% Owner) Buy 65,000 4.31 280,345
2012-08-17 Frost Gamma Investments Trust (10% Owner) Buy 75,000 4.28 321,300
2012-08-16 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.23 253,979
2012-08-15 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.19 167,600
2012-08-14 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.19 188,595
2012-08-13 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.22 253,260
2012-08-10 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.24 423,600
2012-08-09 Frost Gamma Investments Trust (10% Owner) Buy 70,000 4.26 297,920
2012-08-08 Frost Gamma Investments Trust (10% Owner) Buy 47,500 4.25 201,922
2012-08-07 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.28 214,000
2012-08-06 Frost Gamma Investments Trust (10% Owner) Buy 115,000 4.28 492,430
2012-08-03 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.27 256,260
2012-08-02 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.13 412,600
2012-08-01 Frost Gamma Investments Trust (10% Owner) Buy 200,000 4.12 823,199
2012-07-31 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.24 424,099
2012-07-30 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.32 431,799
2012-07-27 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.34 433,600
2012-07-26 Frost Gamma Investments Trust (10% Owner) Buy 185,000 4.34 803,085
2012-07-25 Frost Gamma Investments Trust (10% Owner) Buy 65,000 4.41 286,390
2012-07-23 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.47 179,000
2012-07-20 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.50 135,000
2012-07-19 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.61 115,250
2012-07-18 Frost Gamma Investments Trust (10% Owner) Buy 32,500 4.64 150,962
2012-07-17 Frost Gamma Investments Trust (10% Owner) Buy 85,000 4.58 389,725
2012-07-13 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.61 207,585
2012-07-12 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.59 137,850
2012-07-11 Frost Gamma Investments Trust (10% Owner) Buy 92,500 4.55 421,059
2012-07-10 Frost Gamma Investments Trust (10% Owner) Buy 90,000 4.61 415,080
2012-07-09 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.65 209,250
2012-07-06 Frost Gamma Investments Trust (10% Owner) Buy 90,000 4.70 423,089
2012-07-05 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.76 237,800
2012-07-03 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.71 211,860
2012-07-02 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.64 232,100
2012-06-29 Frost Gamma Investments Trust (10% Owner) Buy 42,500 4.59 194,947
2012-06-28 Frost Gamma Investments Trust (10% Owner) Buy 77,500 4.56 353,632
2012-06-27 Frost Gamma Investments Trust (10% Owner) Buy 12,500 4.62 57,762
2012-06-26 Frost Gamma Investments Trust (10% Owner) Buy 17,500 4.62 80,797
2012-06-25 Frost Gamma Investments Trust (10% Owner) Buy 12,500 4.62 57,750
2012-06-22 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.57 137,100
2012-06-19 Frost Gamma Investments Trust (10% Owner) Buy 77,500 4.47 346,657
2012-06-18 Frost Gamma Investments Trust (10% Owner) Buy 65,000 4.50 292,630
2012-06-15 Frost Gamma Investments Trust (10% Owner) Buy 200,000 4.60 920,800
2012-06-14 Frost Gamma Investments Trust (10% Owner) Buy 85,000 4.69 398,480
2012-06-13 Frost Gamma Investments Trust (10% Owner) Buy 35,000 4.79 167,615
2012-06-12 Frost Gamma Investments Trust (10% Owner) Buy 5,000 4.75 23,760
2012-06-11 Frost Gamma Investments Trust (10% Owner) Buy 42,500 4.77 202,555
2012-06-08 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.71 117,850
2012-06-07 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.60 207,090
2012-06-05 Frost Gamma Investments Trust (10% Owner) Buy 27,500 4.50 123,640
2012-06-04 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.49 89,740
2012-06-01 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.49 134,700
2012-05-31 Frost Gamma Investments Trust (10% Owner) Buy 110,000 4.61 506,990
2012-05-30 Frost Gamma Investments Trust (10% Owner) Buy 35,000 4.66 162,925
2012-05-25 Frost Gamma Investments Trust (10% Owner) Buy 15,000 4.81 72,150
2012-05-24 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.75 118,625
2012-05-23 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.59 91,800
2012-05-22 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.61 92,200
2012-05-21 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.54 90,700
2012-05-18 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.50 179,800
2012-05-17 Frost Gamma Investments Trust (10% Owner) Buy 84,500 4.50 379,827
2012-05-17 Lerner Richard A (Director) Buy 4,400 4.50 19,791
2012-05-16 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.61 138,150
2012-05-16 Lerner Richard A (Director) Buy 50,000 4.60 230,050
2012-05-15 Frost Gamma Investments Trust (10% Owner) Buy 110,000 4.60 505,560
2012-05-14 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.56 455,999
2012-05-11 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.52 451,999
2012-05-10 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.49 448,600
2012-05-09 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.44 44,370
2012-05-08 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.43 132,990
2012-05-04 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.51 225,550
2012-05-02 Frost Gamma Investments Trust (10% Owner) Buy 80,000 4.65 372,080
2012-05-01 Frost Gamma Investments Trust (10% Owner) Buy 32,000 4.69 150,016
2012-04-30 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.77 214,695
2012-04-26 Frost Gamma Investments Trust (10% Owner) Buy 200,000 4.83 966,400
2012-04-25 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.87 48,650
2012-04-24 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.85 96,960
2012-04-23 Frost Gamma Investments Trust (10% Owner) Buy 60,000 4.88 292,560
2012-04-20 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.87 48,700
2012-04-19 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.76 142,710
2012-04-18 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.64 46,360
2012-04-17 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.61 92,100
2012-04-13 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.41 440,599
2012-04-12 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.52 451,600
2012-04-11 Frost Gamma Investments Trust (10% Owner) Buy 100,000 4.52 452,200
2012-04-10 Frost Gamma Investments Trust (10% Owner) Buy 110,000 4.45 489,609
2012-04-09 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.63 231,750
2012-04-05 Frost Gamma Investments Trust (10% Owner) Buy 30,000 4.79 143,580
2012-04-04 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.70 47,000
2012-04-03 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.81 192,240
2012-04-02 Frost Gamma Investments Trust (10% Owner) Buy 45,000 4.69 210,915
2012-03-29 Rubin Steven D (Executive VP-Administration) Buy 2,000 4.68 9,360
2012-03-29 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.71 235,600
2012-03-29 Hsiao Jane Ph D (Vice Chairman & CTO) Buy 10,000 4.71 47,110
2012-03-28 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.75 95,100
2012-03-27 Frost Gamma Investments Trust (10% Owner) Buy 15,000 4.80 72,045
2012-03-26 Frost Gamma Investments Trust (10% Owner) Buy 13,000 4.86 63,180
2012-03-23 Frost Gamma Investments Trust (10% Owner) Buy 33,000 4.85 159,984
2012-03-22 Frost Gamma Investments Trust (10% Owner) Buy 15,000 4.81 72,150
2012-03-21 Frost Gamma Investments Trust (10% Owner) Buy 5,000 4.93 24,674
2012-03-20 Frost Gamma Investments Trust (10% Owner) Buy 16,000 4.88 78,080
2012-03-16 Frost Gamma Investments Trust (10% Owner) Buy 620,000 4.98 3,063,798
2012-03-12 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.83 96,500
2012-03-06 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.72 118,050
2012-03-05 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.79 119,750
2012-02-22 Frost Gamma Investments Trust (10% Owner) Buy 500,000 4.73 2,363,500
2012-02-15 Frost Gamma Investments Trust (10% Owner) Buy 40,000 5.13 205,040
2012-02-13 Frost Gamma Investments Trust (10% Owner) Buy 10,000 5.09 50,950
2012-02-10 Frost Gamma Investments Trust (10% Owner) Buy 10,000 5.12 51,210
2012-02-09 Frost Gamma Investments Trust (10% Owner) Buy 11,167 5.18 57,845
2012-02-08 Frost Gamma Investments Trust (10% Owner) Buy 10,000 5.21 52,120
2012-02-06 Frost Gamma Investments Trust (10% Owner) Buy 5,000 5.24 26,200
2012-02-01 Frost Gamma Investments Trust (10% Owner) Buy 5,000 5.25 26,250
2012-01-31 Frost Gamma Investments Trust (10% Owner) Buy 5,000 5.25 26,275
2012-01-24 Frost Gamma Investments Trust (10% Owner) Buy 10,000 5.10 50,980
2012-01-13 Frost Gamma Investments Trust (10% Owner) Buy 10,000 5.02 50,190
2012-01-12 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.97 49,750
2012-01-11 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.94 49,390
2012-01-10 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.95 49,520
2012-01-09 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.93 49,349
2012-01-06 Frost Gamma Investments Trust (10% Owner) Buy 12,500 4.92 61,487
2012-01-05 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.86 97,280
2012-01-04 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.78 47,750
2012-01-03 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.88 48,800
2011-12-29 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.79 47,910
2011-12-28 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.83 48,310
2011-12-27 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.83 48,350
2011-12-23 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.79 47,890
2011-12-22 Frost Gamma Investments Trust (10% Owner) Buy 15,000 4.76 71,475
2011-12-21 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.81 96,240
2011-12-20 Frost Gamma Investments Trust (10% Owner) Buy 40,000 4.79 191,720
2011-12-14 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.75 95,000
2011-12-13 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.82 96,300
2011-12-12 Frost Gamma Investments Trust (10% Owner) Buy 10,000 4.81 48,130
2011-12-09 Frost Gamma Investments Trust (10% Owner) Buy 20,000 4.83 96,600
2011-12-07 Frost Gamma Investments Trust (10% Owner) Buy 50,000 4.88 244,050
2011-12-05 Frost Gamma Investments Trust (10% Owner) Buy 25,000 5.02 125,550
2011-11-29 Frost Gamma Investments Trust (10% Owner) Buy 25,000 4.77 119,300
2011-11-28 Frost Gamma Investments Trust (10% Owner) Buy 10,000 5.04 50,400

Insider trading activities including stock purchases, stock sales, and option exercises of OPK listed in the above tables cannot be completely guaranteed as to their accuracy. For more insider trading information of Opko Health, Inc. (symbol OPK, CIK number 944809) see the Securities and Exchange Commission (SEC) website.